GEA Pharma Systems Small Scale Solid Dosage R&D A complete ...

Nica Pellet ProcessingModular conceptThe unique modular concept of the Nica PelletizingSystem facilitates optimized solutions to meet processneeds exactly.Mixer / granulator, extruder and spheronizer modules arecombined to create a complete integrated pellet productionplant, or selected individually to suit specific requirements.Modules can be operated in either batch or continuous mode,for maximum flexibility of operation, and can be used standalone,or integrated with other up- or down-stream equipmentsuch as fluid bed processing systems.Ideal for both product development and full-scale productionapplications, process scale-up of the Nica Pelletizing Systemis easy – it’s simply a factor of processing time.Nica ExtruderThe Nica Extruder is based on unique low-shear technologydesigned to minimise work input and temperature rise. It isideal for sensitive products which could be damaged by moreintensive systems. A wide range of extrusion screen sizes andconfigurations are offered for optimisation of pellet diameter,surface quality and size distribution.Used for both batch and continuous production, the NicaExtruder has no stagnant areas, and no significant producthold-up. A compact design eases installation and cleaning.With a simple reconfigurationof the extruder, formulationsthat require a highdegree of work inputcan beprocessed.Nica SpheronizerThe Nica Spheronizer features a smooth-edged, close-fittingfriction wheel for good sphericity of pellets and a tight pelletsize distribution. This patented design eliminates problems ofedge-milling and undesirable fines common with traditionaltechnology. Optimisation of the process is achieved by choice ofcycle time, wheel speed, product loading, friction pattern andregulation of air-flow past the wheel periphery.The Nica Spheronizer is fed directly by the Nica Extruder.For high volume applications, two batch spheronizers may befed by a single continuous extruder.• Good pellet sphericity• Produces no fines• Versatile system• Easy to operate• Easy to clean• Efficient low-sheartechnology• Wide choice ofextrusion screens• Gentle on product• Small foot-print• Easy to cleanExtrusion E-Connect E-140Typical Production Rate 0.1—0.5 kg/min 0.5-2.0 kg/minMinimum Batch Size 50g 200gSpheronizing S-Connect S-320 S-450Typical Batch Range 50g—250g 200g –1.0kg 400g—2.0kg12