Wel1come Trust - Wellcome Trust

to establish an electron microscope unit to study peripheral nervedisease. The work on the neurological and neuropathological effectsof Vitamin B12 deticiency and chronic cyanide intake is referred toin the section on nutrition (page 39).The work of Professor A. S. Paintal in the Vallabhbhai Patel ChestInstitute at Delhi on the neurological control of respiration hasalso attracted the attention of the Trustees. They have given himequipment and supported visitors to go and work with him. Someof his studies are related to the neurological defects caused byleprosy.Endocrine disordersThe hormonal regulation of the animal body continues to be ofgreat interest not only because each year we are able to understandmore about the way that hormones act and how their secretion iscontrolled but also because new hormones are still being discovered.The Endocrine -Unit at Hammersmith where the team directed byProfessors Russell Fraser and lain McIntyre is supported by theTrust continues to work on calcium metabolism, and the part playedby calcitonin and the effects of diabetes.The Trustees have also helped Professor A. G. Everson-Pearce atthe Royal Postgraduate Medical SChool, Hammersmith to extendhis investigations. He has observed that in the intestine there aregroups of so-called APUD cells which have a similar structure toother groups which are known to produce hormones. He is studyingthose cells in the hope that they can be shown to secrete hormoneswhich have not yet been discovered.The value of the new radioimmunoassay methods for detectingsmall quantities of hormones is very important in the developmentof endocrinology. These methods are being used to study theThyroid Stimulating Hormone (TSH) and the Long Acting ThyroidStimulator (LATS) in the Endocrinology Unit oftheDepartment ofMedicine in Newcastle. The team doing this work is led by ProfessorR. Hall, a former Wellcome Senior Research Fellow. Dr. W. R.Greig of the University of Glasgow works on the thyroid andespecially the long-term effect of radiation treatment. He has beengiven a University Award.34