Practical-Manual-Scores-Algorithms-Haemostasis-Thrombosis

Other thrombotic conditionsRisk of venous thromboembolism in cancer PatientsIndicationAssessing the risk of DVT or PE in outpatients with cancer on chemotherapy(Khorana model), the prediction of recurrence (Ay and Ottawa models) andthe risk of DVT in patients with multiple myeloma treated with thalidomide orlenalidomide.Khorana model: for outpatients with cancer on chemotherapyFeatureSite of cancer (origin)• High risk (pancreas, stomach)• Low risk (lung, lymphoma, gynaecologic, bladder, testicular)PointsPlatelet count ≥ 350 × 10 9 /L 1Haemoglobin level < 100 g/L or use of red cell growth factor 1Leukocyte count > 11 × 10 9 /L 1BMI ≥ 35 kg/m 2 1Probability• Low risk 0• Intermediate risk 1-2• High risk > 321InterpretationThe risk of thrombosis was 0.3-0.8% for low-risk patients; 1.8-2.0% forintermediate-risk patients and 6.7-7.1% for high-risk patients; in the latterthromboprophylaxis should be considered.32