Transription - UMK CARNIVORES 3
Transription - UMK CARNIVORES 3
Transription - UMK CARNIVORES 3
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Initiation-RNA synthesis begins at promoters• RNA Pol attaches to promoterregion-forms a close complex,promoter DNA is stably boundbut not unwound• RNA Pol melts the helicalstructure (~12-15bp from -10region to +2 and +3) andseparates the 2 strands of DNAlocally – open promotercomplex• RNA Pol initiates RNA synthesis.The site at which the 1 st nt isadded – start site/point11