Transription - UMK CARNIVORES 3

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Initiation• The association of ribosome and RNA will form preinitiation complex• Pre initiation complex is guided for initiation codon AUG by Shine Dalgarnosequence• Precise positioning is needed for initiation• Bacterial ribosomes have 3 sites: Peptidyl (P) – binds a TRNA that carries a peptide chain Aminoacyl (A) – binds incoming aminoacyl TRNA E (exit)-carries uncharged TRNA that is about to be released from the ribosome34
Initiation• The initiating 5’AUG is positioned in at the P site- the only site fMettRnafmet can bind• fMet-tRna fmet is the only aminoacyl Trna that binds first to the Psite, as during the elongation stage all incoming aminoacyl-trnabinds first to the A and only to the P and E• IF-1 binds at the A site and prevents Trna binding at this site duringinitiation35
Page 3: Transcription• The process of mak
Page 7 and 8: • Synthesized the transcription
Page 9 and 10: Initiation-RNA synthesis begins at
Page 11: Initiation-RNA synthesis begins at
Page 14 and 15: Chain termination1) Intrinsic termi
Page 17 and 18: RNA ProcessingAdditional modificati
Page 19 and 20: RNA Processing2) 3’ Poly A tail
Page 21 and 22: TASKList down the antibiotics that
Page 23 and 24: • Protein are end products of mos
Page 25 and 26: Genetic codeImportant features:•
Page 27: Transfer RNA (TRNA)27
Page 30 and 31: STEPS IN PROTEIN SYNTHESIS• Activ
Page 32 and 33: Initiation• Prot synth begin at t
Page 36 and 37: InitiationStep 2:• The complex is
Page 38 and 39: ElongationRequire:• The initiatio
Page 40 and 41: ElongationStep 2: Peptide bond form
Page 42: TASK• List down the antibiotics t

Transription - UMK CARNIVORES 3

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