Transription - UMK CARNIVORES 3

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Chain termination1) Intrinsic termination/rho independent termination•Controlled by termination sites – specific sequences on the DNA moleculefunction as the signal for termination of transcription process•Two inverted repeats spaced by few other based followed by repeats ofAdenosine•Inverted repeats – sequences of bases that are complementary, they can loopback on themselves•When the RNA is created, the inverted repeats form a hairpin loop and stallthe advancement of RNA Pol•The presence of uracils cause a series of A-U base pairs between thetemplate strand and the RNA, and relatively unstable•RNA dissociate from the transcription bubble- end of transcription14
Chain termination2) The rho (ρ) factor mechanism• Rho protein binds to the RNAand chases the RNA Pol.• When the RNA Pol pause atthe termination site,the rho protein has a chanceto catch up the RNA Pol• Rho proteins reaches thetermination site, it facilitatethe dissociation of thetranscription machinery byunwinds the DNA-RNA hybridin the transcription bubble15
Page 3: Transcription• The process of mak
Page 7 and 8: • Synthesized the transcription
Page 9 and 10: Initiation-RNA synthesis begins at
Page 11: Initiation-RNA synthesis begins at
Page 17 and 18: RNA ProcessingAdditional modificati
Page 19 and 20: RNA Processing2) 3’ Poly A tail
Page 21 and 22: TASKList down the antibiotics that
Page 23 and 24: • Protein are end products of mos
Page 25 and 26: Genetic codeImportant features:•
Page 27: Transfer RNA (TRNA)27
Page 30 and 31: STEPS IN PROTEIN SYNTHESIS• Activ
Page 32 and 33: Initiation• Prot synth begin at t
Page 34 and 35: Initiation• The association of ri
Page 36 and 37: InitiationStep 2:• The complex is
Page 38 and 39: ElongationRequire:• The initiatio
Page 40 and 41: ElongationStep 2: Peptide bond form
Page 42: TASK• List down the antibiotics t

Transription - UMK CARNIVORES 3

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