Sample Size and Power
Sample Size and Power
Sample Size and Power
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<strong>Sample</strong> <strong>Size</strong> Differences• If the null hypothesis (H 0 ) is true• Using two-stage optimal design– On average 26 subjects enrolled• Using a 1-sample test of proportions– 34 patients– If feasible• Using a 2-sample r<strong>and</strong>omized test ofproportions– 86 patients per group