Gene-Environment Interaction - Zentrales ADHS Netz

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Effect maternal smoking on IQ, whole groupP < 0.05• Significant main effect of smoking onIQcorrected for: birth weight, parental occupationstatus, centre, maternal alcohol use duringpregnancy• No main gene effects on IQ, and noGxE interaction effects on IQ• Parental educational status strongpredictor for IQIQ1011009998979695949392none 1-5 cig 6 ormoreF(2, 538.01) = 4.19, p = 0.016
Effect maternal smoking on IQ, separately in ADHD and non-ADHD10210098IQ96949290none1 - 5 cig6 or more88ADHDnon-affected siblingsF (2, 363.1) = 4.04, p = 0.018 F (2, 285.1)=0.79, p = 0.451
Page 1 and 2: Gene-Environment InteractionJan K.
Page 3 and 4: Complicating factors in genetic stu
Page 5 and 6: GxE and ADHD - current findings•
Page 7 and 8: International Study of the Mapping
Page 9 and 10: Prenatal maternal smoking & ADHD -
Page 11 and 12: Parental smoking• Collected by qu
Page 13 and 14: Percentage maternal and paternal sm
Page 15 and 16: Smoking, ADHD / non-ADHD, and atten
Page 17 and 18: Results• Paternal smoking is sign
Page 19 and 20: Maternal smoking & IQ (Frazier et a
Page 21 and 22: Genes related to ADHD may affect IQ
Page 23 and 24: MethodsUnited KingdomIrelandNetherl
Page 25: Statistical AnalysesLinear Mixed Mo

Gene-Environment Interaction - Zentrales ADHS Netz

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