Prevention & Cure â Dieter Schmidt

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Roadmap: How to achieve the goal• <strong>Prevention</strong> of epileptogenic brain injury• Discovery and preclinical development ofantiepileptogenic drugs (AEG)• Innovative clinical AEG trial design• Summary and Conclusions

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% of PatientsSurgical cure: Seizure free off AEDsafter temporal lobe surgery50454035302520151050Kelley and Theodore 20051 year (48) 5 years (48) 10 years (48) 30 years (45)SF no AEDs SF on AEDs NSF dead• 104 of 365 (28%) seizure-free adults had discontinued AEDs after epilepsy surgery(de Tisi et al. 2011)

Page 5 and 6: Roadmap: How to achieve the goal•
Page 7 and 8: Roadmap: How to achieve the goal•
Page 9 and 10: Opportunities for disease modificat
Page 11 and 12: European Study of Epilepsy Preventi
Page 13: Cure of childhood-onset epilepsy: n

Prevention & Cure â Dieter Schmidt

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Prevention & Cure â Dieter Schmidt