Haemophilus influenzae

Haemophilus influenzaeBeta-lactamase*Amoxicillin/clav. acidCefuroximeCeftriaxoneDoxycyclineNalidixic acid**Erythromycin***Trim/sulfaprimaryXXXXXXXreportamoxicillinXXXXcipro/levo/moxiazithromycinX*Use beta-lactamase result to deduce susceptibility of amoxicillin**nalidixic acid used as indicator to deduce the susceptibility of ciprofloxacin, levofloxacin andmoxifloxacin*** erythromycin used to deduce the susceptibility of azithromycin, clarithromycin and roxithromycin,weak correlation exists between macrolide MICs and clinical outcome resulting in an“intermediate”categorization of the WT

Moraxella catarrhalisAmoxicillin/clav. acidCeftriaxoneCotrimoxazolDoxycyclineNalidixic acid*Erythromycin**primaryXXXXXXreportXXXXcipro/levo/moxiX*nalidixic acid used as indicator to screen for fluoroquinolone resistance**erythromycin used to deduce the susceptibility of azithromycin, clarithromycin androxithromycin

Streptococcus pneumoniaeOxacillin*ErythromycinDoxycyclineNorfloxacin**Cefotaxim/Ceftriaxon***Trim/sulfaprimaryXXXXXXreportpenicillinXXlevo/moxiXX*oxacillin is used as indicator to deduce the susceptibility of penicillin or amoxycillin**Norfloxacin is used as indicator to deduce the susceptibility of levofloxacin ormoxifloxacin*** cefotaxim/ceftriaxon susceptibilty is deduced from oxacillin screen result

Neisseria meningitidesprimary secondary reportPenicillinAmpicillin*CefotaximeCeftriaxonRifampicin (prophylaxis)Ciprofloxacin (prophylaxis)Tetracycline (prophylaxis)**X??XX??XX??X??XX*According to literature data ampicillin would be a better indicator than penicillin to detectreduced susceptibility**tetracycline can be used as indicator to deduce the susceptibility of minocycline

Streptococcus group A,B,C and GPenicillinNorfloxacin*Erythromycin**Clindamycin***DoxycyclineTrim/SulfaprimaryXXXXXXreportXlevo/moxiXXXX*Norfloxacin is used as indicator to deduce the susceptibility of levofloxacin or moxifloxacin**erythromycin is used to deduce the susceptibility of azithromycin, clarithromycin androxithromycin***look for antagonism between erythromycin and clindamycin (D-test)

Enterococcus spp.AmpicillinVancomycinTeicoplaninLinezolidGentamicin high levelNitrofurantoin*primaryXXXXXXreportXXXXXX* Valid for E. faecalis only in case of uncomplicated UTI

Helicobacter pyloriAmoxicillinClarithromycinMetronidazoleTetracyclinelevofloxacinprimary secondary reportXXXXXXXXXX

Campylobacter jejuni/coliErythromycin*CiprofloxacinDoxycyclineprimaryXXXreportXXX*erythromycin is used to deduce the susceptibility of erythromycin, azithromycin andclarithromycin