Abstracts – 2008 - Obstetricia Crítica

were more likely to be among women younger than 24 years than the cocaineabuseor non-substance-abuse hospitalizations. Most medical conditions weremore prevalent in the amphetamine-abuse group than the non-substance-abusegroup. When the substance abuse groups were compared with each other,obstetric diagnoses associated with infant morbidity such as premature deliveryand poor fetal growth were more common in the cocaine-abuse group, whereasvasoconstrictive effects such as cardiovascular disorders and hypertensioncomplicating pregnancy were more common in the amphetamine-abuse group.CONCLUSION: As pregnancy hospitalizations with a diagnosis of amphetamineabuse continue to increase, clinicians should familiarize themselves with theadverse consequences of amphetamine abuse during pregnancy and evidencebasedguidelines to deal with this high-risk population. LEVEL OF EVIDENCE:III.Am J Obstet Gynecol. 2008 Jan 31 [Epub ahead of print]Preeclampsia as a risk factor for cardiovascular disease later in life:validation of a preeclampsia questionnaire.Diehl CL, Brost BC, Hogan MC, Elesber AA, Offord KP, Turner ST, Garovic VD.Division of Obstetrics and Gynecology.OBJECTIVE: This study was undertaken to validate a self-administeredquestionnaire in verifying the diagnosis of preeclampsia, eclampsia, or toxemia ina group of women with a greater than 20-year history of preeclampsia. STUDYDESIGN: Questionnaires were mailed to a random sample of 144 women whoreceived a diagnosis of any of these 3 conditions and 158 women who hadnormotensive pregnancies at Mayo Clinic, Rochester, Minnesota, from 1960-1979. RESULTS: A previous diagnosis of preeclampsia, eclampsia, or toxemiawas verified with 80% sensitivity and 96% specificity. CONCLUSION: Ourvalidated questionnaire may be a useful research tool in identifying women with aprevious history of preeclampsia. Women with a history of preeclampsia had ahigher prevalence of future hypertension than those with a history ofnormotensive pregnancy.Am J Obstet Gynecol. 2008 Jan 31 [Epub ahead of print]Pregnancies in glycogen storage disease type Ia.Martens DH, Rake JP, Schwarz M, Ullrich K, Weinstein DA, Merkel M, Sauer PJ,Smit GP.Department of Pediatrics, Beatrix Children's Hospital, University Medical CenterGroningen, the Netherlands.OBJECTIVE: Reports on pregnancies in women with glycogen storage diseasetype Ia (GSD-Ia) are scarce. Because of improved life expectancy, pregnancy isbecoming an important issue. We describe 15 pregnancies by focusing ondietary treatment, biochemical parameters, and GSD-Ia complications. STUDYDESIGN: Carbohydrate requirements (milligrams per kilogram per minute),triglyceride and uric acid levels, liver ultrasonography, and creatinine clearancewere investigated before, during, and after pregnancy. Data from the newborninfants were obtained from the records. RESULTS: In the first trimester, a