Paediatric cardiology clinical profile - University Hospital ...

COMMON DRUGS USED IN PAEDIATRIC CARDIOLOGYDiureticsFRUSEMIDE (Furosemide)Uses :Dose :Side-effects :Interactions :Strong loop diureticRemoves fluid from around heart and lungsUseful in management and prevention of CCFTreatment of hypertensionUsually 1mg/kg oral, NG or IVMay be given QDSLow potassium due to strong diuretic effectHypotension due to strong diuretic effectDecrease in diuresis with NSAID’sMore profound hypotensive effect if used alongside ACE inhibitors or beta blockersSPIRONOLACTONEUses :Dose :Side-effects :Weak diureticPotassium sparing-used alongside Frusemide to maintain potassium levelManagement and prevention of CCFUsually 1mg/kg oral or NGMay be given QDSRisk of developing high potassium if given at higher dosesInteractions :Notes :Increased potassium level with ACE inhibitorsIncreased potassium levels with NSAID’sMay elevate Digoxin level-risk of toxicityMay be given alongside Captopril until maintenance dose is achieved, thendiscontinued as risk of high potassium.