Agilent 1120 Compact LC - T.E.A.M.

Introducing the Agilent 1120 Compact LCSimply a better value.Is your lab looking for better, more reproducible results for all your standard HPLC analyses, run after runand day after day? Are you looking for an affordable, high quality solution that maximizes uptime, minimizesmaintenance and provides the highest return on your investment?Here’s some good news: the new 1120 Compact LC from Agilent.Now any lab can take advantage of Agilent’s unmatched combination of advanced instrumentation, versatilesoftware and application-matched columns and consumables. This robust new LC solution is designed tooptimize performance, while minimizing complexity. And because it’s from Agilent, it gives you the provenquality and performance you expect from the industry leader, in your choice of five easy to own, integrated,“all-in-one” configurations.Easy to learn and use – for all users.With simple, intuitive Agilent EZChrom Elite Compactsoftware and built-in self-diagnostics, the 1120 CompactLC is easy to operate and easy to maintain. Because everysystem is thoroughly tested in its final configuration beforeshipping, startup is fast and trouble-free. Right out of thebox, even inexperienced or infrequent users can quicklymaster the system and produce first-rate results.Extraordinary results in a systemoptimized for everyday productivity.Run-after-run, day-after-day reproducibility. Exceptional accuracy.Superior precision. For all your routine applications – includingthose that must comply with regulatory requirements – the 1120Compact LC offers uncompromising LC performance.Industry-leading quality andlong-life Agilent reliability.Why settle for “good enough,” when you can invest in quality?With a 30-year history of success and an installed base ofmore than 60,000 LC systems, Agilent has earned a worldwidereputation for reliability and uptime under the most demandingoperating conditions.EZChrom Elite Compact software makes it easy for all your users toset up and operate the system.Absorbance [mAU]600400200012Peak % RSD RT % RSD Area12340.050.080.090.090.220.300.190.090 1 2 3 4 5 6 7 8 9 10 11Time [min]Excellent reproducibility of retention times and areas from six repetitiveisocratic analyses of a standard sample – with 3 µL injection volume.342

Agilent’s 1120 Compact LC delivers the performance you are looking for and reliability you can count on – as well as today’s lowestcost of ownership!A simply perfect choice for labs like yours.The Agilent 1120 Compact LC was developed specifically toaddress the needs of small- to medium-sized labs that aremainly concerned with routine analyses using standard HPLCmethods. In keeping with its mission, the system delivers all theperformance needed to meet stringent regulatory demands –while setting new standards for compactness, ease of operationand serviceability.To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 3

Simply more in tunewith your lab’s needs.Take a close look at the Agilent 1120 Compact LC and you’ll find everything you need for first-class resultsand rewarding day-after-day productivity. And, because you’re too busy to worry about complicated featuresyour lab is unlikely to use, you’ll be pleased to find there’s nothing there you don’t need.Five standard configurations to fit your LC workflowIsocratic ConfigurationsGradient ConfigurationsIsocratic PumpIsocratic PumpGradient PumpGradient PumpGradient PumpManual InjectorAutosamplerManual InjectorManual InjectorAutosampler—Column Oven—Column OvenColumn OvenVariable WavelengthDetectorVariable WavelengthDetectorVariable WavelengthDetectorVariable WavelengthDetectorVariable WavelengthDetectorAgilent’s LC detectors are fully compatible with the 1120 Compact LC. Additional external detection choices include:• Refractive Index (RID) • Fluorescence (FLD) • Evaporative Light Scattering (ELSD)Solvent deliveryThe optimized design of the pumping module used in theAgilent 1120 LC ensures stable, virtually pulse-free solventflow up to 10 mL/min. Servo-controlled, dual floating pistonsenable variable stroke volume optimized for the selected flowrate, and keeps maintenance to a minimum. Choose fromdifferent configurations, including either an isocratic pumpor a gradient pump with up to two solvents and integratedtwo-channel degasser.DegasserThe gradient pump includes an integrated dual-channeldegasser with continuous vacuum using Teflon AF technology,which provides low internal volumes of 1.5 mL per channel.The degasser eliminates baseline fluctuations and shortensequilibration times.Pump options• Automated solvent selection valve for gradient pump –combines two-out-of-four solvents for gradient formationor for column flushing with different solvents.• Continuous seal wash kit to prevent corrosion forapplications running buffer solutions with high saltconcentrations greater than 0.1 M.Gradient pump and integrated degasser4

Manual injectorAn easy to use, easy to maintain solution for low throughputsampling, the manual injector includes a long-life Rheodyne2-position, 6-port sample injection valve and standard 20 µLloop. Front access to the valve facilitates easy sample injectionand straightforward exchange of sample loops.AutosamplerThe integrated autosampler is designed for reliability, safety,and easy maintenance, and facilitates reliable injections from0.1 to 100 µL. The unit delivers high precision as well asexcellent linearity over a wide volume range. The autosampler’sflow-through design ensures that there is no loss of sample;the entire sample drawn from the vial is injected. The standardconfiguration offers a sample capacity of 100 2-mL vials;alternatively, two half-trays each with 40 2-mL vials or 156-mL vials can be used.Column ovenThe 1120 Compact LC's available column oven houses a singlecolumn, and provides accurate, stable column temperaturefrom 10 degrees above ambient to 60°C, for applicationswhere retention time reproducibility and separation qualityimprove above ambient temperatures.Variable wavelength detectorFeaturing simplified optics for high sensitivity, low baselinedrift and wide linear range, Agilent’s variable wavelengthdetector not only lowers your detection limits; it lowersyour cost of ownership with easy front access forfast lamp and flow cell replacement.Manual injectorAutosamplerColumn ovenVariable wavelength detectorAbsorbance [mAU]4540353025201510505.1545.309Impurities8.803Ibuprofen11.686Absorbance [mAU]403020100124356789Peak Compound1 Metamitron2 Chloridazone3 Cyanazine4 Simazine5 Prometryn6 Diuron7 Propazine8 Terbuthylazine9 Chlortoluron0 1 2 3 4 5 6 7 8 9 10 11 12 13Time [min]Analysis of a pharmaceutical preparation, showing the activeingredient ibuprofen and three earlier-eluting impurities.0 2 4 6 8 10 12 14Time [min]Trace analysis of pesticide residues, showing a limit of detection(LOD) of less than 100 pg. The relative standard deviation is lessthan 0.08 % for retention times and less than 0.5 % for areas.To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 5

Simply easier to learn,to use – and to live with.A complete, integrated software solutionWith the bundled EZChrom Elite Compact software, it’s easyto put all of the capabilities of the 1120 Compact LC to workin your lab. A fast, powerful chromatography data system,EZChrom Elite Compact provides full control of two 1120Compact LCs from a single PC. EZChrom Elite Compactincludes comprehensive data processing, flexible reportingand the full range of capabilities you would expect from amodern chromatography work station.Regulatory compliance – made easy.EZChrom Elite Compact provides comprehensive toolsto help you address all the requirements of GLP/GMPand 21 CFR Part 11 compliance. With built-in audittrails, multi-user login security, user permissions, andelectronic signatures, the software made easy for yourlaboratory to operate in any regulated environment.Quick access to common tasks. View instrument status, currentdata and run queue on a single screen—and perform a runwith just a couple of mouse clicks.Scalable from a single user to a whole enterprise.As a scalable part of the Agilent informatics portfolio, your EZChrom Elite Compact software can grow as your lab grows. Upgrade toEZChrom Elite Workstation and add control for over 330 chromatographic components from more than 25 vendors. Expand furtherto full client-server deployment, or all the way to Agilent’s enterprise-wide OpenLAB solution. No matter how your lab’s needs evolve,your data, methods, sequences and reports will still be readable. And, because the user interface is the same across the full productline, you won’t have to retrain your operators.From EZChrom Elite Compact to Workstation to Client/Server, EZChrom Elite software can be easily scaled up to meet the changing needs of a growing lab.6

Agilent columns and supplies—an extrameasure of reliability and confidence.Whatever your lab is analyzing, every method requiresday-to-day reproducibility and superior reliability. To deliveroptimal performance with all your samples and mobilephase, the Agilent ZORBAX Eclipse Plus columns give youthe performance and consistency you're looking for. Thesecolumns deliver excellent peak shape under a wide rangeof operating conditions for the highest quality, reproducibleresults.Try the Eclipse Plus C18 column included with your 1120Compact LC. You'll appreciate its superior qualitative andquantitative performance. And if you need other columnsthe complete ZORBAX product line will have a choice foryour application. ZORBAX columns and Agilent supplies foryour new compact LC – the products you need to achievepeak productivity – day after day, and year after year.Maximize your uptime with Agilent’s customerenabledservice and support features.The 1120 Compact LC’s integrated hardware and softwaredesign features provide a completely new level of operationalsimplicity. There’s a guided system set-up so that you can getyour new 1120 Compact LC up and running without havingto schedule a visit by an Agilent service representative.Lab Monitor & Diagnostic Software alertsyou to problems before they happen.Now you can detect instrument problems beforethey occur and schedule a convenient time to solvethe problem without it impacting your analysis. Thisis facilitated by an easy-to-use package includedin your system, Lab Monitor and Diagnostics software,that continuously monitors your instrument.From a “lab-at-a-glance” screen that displaysa snapshot of all connected 1120 Compact LCinstruments, to guided diagnostics tests and easyto perform maintenance routines, to a built-in suiteof user information and help, Lab Monitor andDiagnostics software provides all the informationa user needs in one convenient place at one timethus enabling you to maximize your instrument’sefficiency and productivity.Of course, Agilent’s world class customer service engineersand certified support partners are available to provide a fullrange of Agilent services, including installation, familiarization,training, maintenance, contractual repair, and regulatorycompliance support.To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 7

The Agilent Value Promise–10 yearsof guaranteed valueIn addition to continually evolving products, we offer somethingelse unique to the industry—our 10-year value guarantee.The Agilent Value Promise guarantees you at least 10 years ofinstrument use from your date of purchase, or we will credit youwith the residual value of that system toward an upgraded model.Not only does Agilent ensure a safe purchase now, we helpensure your investment is as valuable to you in the long run.The Agilent Service GuaranteeShould your Agilent instrument require service while covered byan Agilent service agreement, we guaranteerepair or we will replace your instrument for free.No other manufacturer or service provider offersthis level of commitment to keeping your laboratory running atmaximum productivity.For more informationLearn more:www.agilent.com/chem/1120Buy online:www.agilent.com/chem/storeFind an Agilent customer center in your country:www.agilent.com/chem/contactusContact us:agilent_inquiries@agilent.com© Agilent Technologies, Inc. 2008Published March 1, 20085989-7372EN