Identification of the Chronic <strong>Wound</strong> TranscriptomeLocationPatient1Patient2Patient3Gene ExpressionProfiles201645_at 219454_at 1.62 7.37 2.01 7.23 1.59 1.81 2.29 2.15 2.25 1.09 1.39 6.79 1.72 6.67 1.36 1.66 1.95 1.98 1.93 1.00 AdhesionCa binding201561_s_at 61734_at -2.34 2.45 -2.26 1.92 -2.06 1.12 -1.61 3.32 -2.12 1.19 -1.72 2.38 -1.66 1.87 -1.51 1.09 -1.18 3.22 -1.56 1.15 AdhesionCa binding201681_s_at 200755_s_at -1.90 3.04 -1.53 1.43 -1.36 1.34 -1.39 3.20 -1.54 1.93 -1.96 2.65 -1.59 1.25 -1.41 1.17 -1.44 2.79 -1.60 1.68 AdhesionCa binding219197_s_at -4.75 -4.34 -8.64 -2.90 -9.01 -3.74 -3.42 -6.81 -2.29 -7.10 Ca binding213369_at -9.14 -2.99 -4.15 -4.67 -5.35 -5.59 -1.83 -2.54 -2.85 -3.27 Adhesion, cadherin202870_s_at 4.25 5.28 8.28 4.01 7.78 3.80 4.72 7.41 3.58 6.96 Cell cycle208153_s_at 204170_s_at -2.46 2.40 -2.11 1.86 -2.50 2.69 -2.00 1.94 -2.51 2.57 -2.00 3.24 -1.72 2.51 -2.03 3.62 -1.62 2.62 -2.04 3.47 Adhesion, Cell cyclecadherin208407_s_at 204026_s_at -1.27 2.43 -1.81 2.11 -1.72 3.28 -1.55 2.00 -1.38 2.94 -1.27 2.39 -1.82 2.07 -1.73 3.23 -1.55 1.96 -1.38 2.90 Adhesion, Cell cyclecadherin204029_at 202388_at -2.18 1.76 -1.95 5.18 -3.09 2.07 -1.40 1.49 -1.59 3.22 -1.80 1.43 -1.61 4.19 -2.55 1.68 -1.16 1.21 -1.32 2.61 Adhesion, Cell cyclecadherin204750_s_at 201853_s_at 12.77 1.14 3.99 1.60 8.96 1.49 5.41 1.82 13.93 1.67 5.38 1.27 1.68 1.78 3.78 1.66 2.28 2.03 5.87 1.87 Adhesion, Cell cycledesmosomal207324_s_at 201371_s_at -61.89 -1.95 -2.80 -2.04 -6.70 -2.20 -1.33 -2.06 -3.31 -2.27 -52.50 -1.77 -2.37 -1.85 -5.69 -2.00 -1.13 -1.87 -2.81 -2.07 Adhesion, Cell cycledesmosomal211382_s_at -4.35 -2.17 -3.35 -2.08 -2.63 -3.31 -1.65 -2.55 -1.58 -2.00 Cell cycle211075_s_at 1.73 1.21 1.96 1.58 2.09 1.57 1.10 1.77 1.44 1.90 Adhesion, integrin201482_at 1.37 1.77 1.75 1.45 2.34 1.33 1.72 1.71 1.41 2.28 Cell cycle inhibitor204455_at -1.78 -1.87 -2.29 -1.37 -1.14 -2.13 -2.22 -2.73 -1.63 -1.36 Adhesion, integrin218346_s_at -3.58 -2.16 -4.65 -2.36 -3.88 -2.59 -1.57 -3.37 -1.71 -2.81 Cell cycle inhibitor210869_s_at 200920_s_at -2.13 3.45 -1.51 1.84 -1.79 2.22 -1.09 2.89 -1.49 2.41 -2.18 2.87 -1.55 1.53 -1.84 1.84 2.40 -1.12 2.00 -1.53 Adhesion, Cell cycle junctional inhibitor203757_s_at 201236_s_at 46.88 -1.77 10.21 -1.13 16.03 -2.54 -1.59 1.38 21.42 -1.79 41.65 -1.57 9.08 1.00 14.24 -2.25 1.23 -1.41 19.04 -1.58 Adhesion, Cell cycle junctional inhibitor201615_x_at 202192_s_at -1.89 2.84 -1.30 1.31 -2.30 1.99 -1.52 2.42 -2.17 1.67 -1.89 2.67 -1.29 1.23 -2.30 1.86 2.27 -1.51 1.57 -2.17 Adhesion, Cell cycle junctional inhibitor205490_x_at 201289_at -2.03 6.77 -2.09 3.52 -1.83 4.17 10.89 -2.30 -1.46 5.94 -1.79 3.71 -1.85 1.93 -1.61 2.28 -2.03 5.97 -1.28 3.26 Adhesion, Cell growth, junctionalproliferation201540_at -2.43 -1.90 -2.81 -1.60 -3.99 -1.55 -1.22 -1.80 -1.02 -2.56 Cell growth, proliferation201470_at 1.91 2.24 3.12 1.55 2.06 1.67 1.96 2.73 1.36 1.80 Antioxidant217733_s_at 2.48 1.95 2.58 1.75 2.30 2.24 1.76 2.33 1.58 2.07 Cytoskeletal202967_at -3.13 -1.93 -2.48 -1.92 -2.27 -3.21 -1.98 -2.55 -1.97 -2.33 Antioxidant205547_s_at 4.79 2.24 1.16 7.06 3.27 5.07 2.37 1.23 7.48 3.46 Cytoskeletal201427_s_at -1.66 -1.61 -3.85 -1.62 -3.20 -1.55 -1.50 -3.59 -1.51 -2.98 Antioxidant202565_s_at -1.22 -1.92 -1.84 -1.71 -1.84 -1.26 -1.98 -1.90 -1.76 -1.90 Cytoskeletal204168_at 204083_s_at -2.57 5.03 -1.94 3.68 -2.14 2.79 -1.81 5.78 -2.22 2.70 -1.85 5.16 -1.39 3.77 -1.53 2.86 -1.30 5.93 -1.59 2.77 AntioxidantCytoskeletal, actin209276_s_at 201954_at -2.60 2.19 -1.53 2.78 -3.26 3.10 -1.09 1.84 -3.43 2.38 -4.62 1.60 -2.72 2.03 -5.80 2.26 -1.94 1.34 -6.10 1.74 AntioxidantCytoskeletal, actin201432_at 211160_x_at -2.41 2.27 -1.99 -2.83 1.98 -1.32 1.74 -1.71 2.89 -2.05 1.86 -1.69 1.64 -2.41 1.63 -1.12 1.43 -1.45 2.38 AntioxidantCytoskeletal, actin202831_at 60528_at -3.46 1.21 -1.25 -1.46 -2.31 -1.80 -2.31 -1.55 -2.94 -1.75 -1.11 -3.66 -1.69 -1.54 -3.11 -1.90 -3.11 -1.64 -3.97 -1.85 AntioxidantCytoskeletal, actin209046_s_at -1.47 -1.57 -1.81 -1.22 -1.51 -1.65 -1.76 -2.02 -1.37 -1.70 Cytoskeletal, actin206662_at -2.32 -1.11 -2.24 -1.34 -2.85 -3.08 -1.48 -2.98 -1.78 -3.79 Antioxidant38340_at -2.34 -1.26 -2.10 -1.80 -1.73 -2.00 -1.08 -1.80 -1.54 -1.48 Cytoskeletal, actin211922_s_at -1.93 -2.25 -3.20 1.06 -1.54 -2.54 -2.95 -4.20 -1.24 -2.02 Antioxidant211776_s_at 5.89 2.13 4.06 1.74 3.04 4.11 1.49 2.84 1.21 2.12 Cytoskeletal, actin, membrane218856_at 200974_at 2.94 3.12 2.23 1.59 2.30 1.30 1.96 2.86 2.23 1.93 3.14 3.49 2.38 1.78 2.45 1.45 2.09 3.19 2.38 2.15 ApoptosisCytoskeletal, actin, motility209230_s_at 200801_x_at -4.09 1.87 -1.94 1.52 -2.97 1.47 -1.52 1.39 -2.56 1.77 -3.19 1.85 -1.51 1.50 -2.32 1.46 -1.19 1.37 -1.99 1.75 ApoptosisCytoskeletal, actin, motility
Location ABench to Bedside: From Microarray Analyses toPatient BiopsiesLocation BControlLocation ALocation BLocation BLocation AGene Expression Profiles