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capsule experience - MG Lorenzatto

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10<br />

Chapter 1<br />

THE OPTICAL DOME<br />

The optical dome and its relationship to the other optical<br />

components create two important advantages in <strong>capsule</strong><br />

endoscopy:<br />

a. Improved illumination efficiency.<br />

b. Favorable imaging geometry within the field of view.<br />

Another minor factor which may be contributing to image<br />

quality is the presence of a fluid interface between the optical<br />

dome and tissue at the time of examination improving the<br />

resolution of different anatomical structures such as villi.<br />

Finally, another advantage of the optical dome is that it lends<br />

itself to cleaning by the GI tract mucosa.<br />

Geometric and optical differences between image acquisition<br />

in wired and wireless endoscopy are compared in Figure 2A<br />

and Figure 2B. Figure 2A depicts the geometrical relationship<br />

for a push enteroscope inserted into the intestine. Geometrical<br />

relationship for the M2A ® <strong>capsule</strong> endoscope is depicted in<br />

Figure 2B. The standard endoscope (Figure 2A) includes an<br />

illumination source (2), and a lens (3), producing the field of<br />

illumination (4), and the field of view (5) shown in Figure 2A.<br />

Collapse of the intestinal wall (6) may obscure either the field<br />

of view or field of illumination. This technical problem is<br />

resolved in standard endoscopy by insufflating the intestine<br />

with air (7), resulting in the distancing of the intestinal muco<br />

from the tip of the endoscope, clearing both the field of view<br />

and the field of illumination. Air insufflation also enables the<br />

operator to orient the tip of the endoscope in the proper<br />

luminal direction, and to advance the endoscope tip accordingly.<br />

Figure 2B shows the wireless <strong>capsule</strong> endoscope (1) in the<br />

intestine. The <strong>capsule</strong> includes its illumination sources (2),<br />

and the lens (3), comprising a field of illumination (4), and a<br />

field of view (5) respectively. In order to prevent collapse of<br />

Physiological Endoscopy<br />

the intestinal wall (6), and resultant obscuring of either the<br />

field of illumination or the field of view, a specially designed<br />

optical dome (8) covers both the source of illumination and<br />

the lens. The space remaining between the dome and the<br />

intestinal wall may at times be occupied by fluid.<br />

Figure 2. Geometrical and optical interrelationships for<br />

the enteroscope and <strong>capsule</strong> endoscope in the<br />

intestine.<br />

A - Push enteroscope<br />

2 - Illumination source<br />

1 - Endoscope inside<br />

intestine<br />

6 - Intestinal wall<br />

B - Capsule endoscope<br />

6 - Intestinal wall<br />

3 - Lens<br />

4 - Field of illumination 5 - Field of view<br />

3 - Lens<br />

1 - Wireless <strong>capsule</strong><br />

endoscope inside<br />

intestine<br />

7 - Air filling, due to insufflation<br />

8 - Optical dome<br />

The field of view of most commercially available endoscopes<br />

is within the range of 120˚-140˚, similar to the M2A ® <strong>capsule</strong><br />

endoscope. Depth of field of the standard endoscope starts<br />

from 3-5mm from the endoscope tip and extends to a distance<br />

of 100 mm. Unlike in the push endoscope, depth of view of<br />

the <strong>capsule</strong> endoscope starts on the optical dome itself.<br />

b<br />

2 - Illumination source<br />

4 - Field of illumination<br />

5 - Field of view<br />

a<br />

7 - Liquid filling,<br />

intestinal<br />

liquids

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