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Approach to Speech Delay

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Differential DiagnosisOther E<strong>to</strong>logiesConditionHearing impairmentPrematurity and/or lowbirthweightGenetic conditionsNeurological conditionsMetabolic conditionsToxinsSocioeconomic fac<strong>to</strong>rsExamplesCongenital (genetic, TORCH) or acquired (medications,infections)Down syndrome, Fragile X, Williams, NF1, TSSeizures, cerebral palsy, brain malformations, headtrauma, intracranial hemorrhageMi<strong>to</strong>chodrial disease, PKU, hypothyroidism, irondeficiencyLead poisoningLack of language stimulation, low socioeconomic status,low parental education, neglect, parental depression, lackof permanency

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