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Extradural Injection of Medication by theSacrococcygeal RouteMR. A. SICARDIn a communication made some time ago to this Society westressed the potential experimental and clinical importanceof injecting diverse substances into the cerebrospinal fluidby the lumbar route.Subsequently, the results of subarachnoid injection ofcocaine (Bier) became known and gave rise to much discussion.This method of analgesia has not only been usedin surgery, particularly by Mr. Tuffier, but was testedby ourselves immediately after Mr. Bier's communication inthe treatment of tabetic lightning pains. Numerous authors,most notably Marie Pitres and Achard Guillain, have usedthis method of medication to relieve neuralgic pain in thelumbar region and in the lower limbs (sciatica, lumbago),and, in the great majority of cases have obtained verysatisfactory results.Unfortunately the subarachnoid injection of cocainepresents incontrovertible disadvantages. We have ourselveson many occasions observed it to be followed by intractableheadache lasting two or three days, sometimes accompaniedby nausea and even by vomiting.* Translated from Sicard, A.: Les injectionsm^dicamenteuses extra-durales par voie sacrococcygienne.Comptes rendus hebdomadaires des stanceset memoires de la Soci£t£ de Biologie, 53:396-398(Apr. 20) 1901.* We will not discuss here the use of this method insurgical operations, which has been reviewed atconsiderable length in communications by Messrs.Tuffier, Reclus and others (in February and March,1901).