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with a little sulfuric acid. The resulting dark brown-greensolution was expressed and filtered and then treated withweak calcium hydrate. This precipitated several substances,including part of the chlorophyll and a wax that could berendered completely colorless. The alkaline liquid soobtained was filtered and neutralized with sulfuric acid,the alcohol was removed by distillation, and the remainderevaporated to dryness in a waterbath. The residue wasmixed with water, resulting in the separation of a darkgreen, semiliquid mass containing the rest of thechlorophyll and in the formation of a yellowish brownsolution which contained the cocaine as a sulfuric acidsalt.Cocaine was deposited by sodium carbonate, as a stillimpure brown precipitate. The base was taken up in ether,which, when diluted, yielded a yellowish, smelly, amorphousresidue in which, however, concentric rings of crystals soonbegan to form. On repeating the treatment with alcoholentirely pure and colorless crystals were obtained.Cocaine crystallizes in small colorless and odorlesscrystals. It is sparingly soluble in water, fairly solublein alcohol, and very soluble in ether. Its reaction isstrongly alkaline. It tastes bitter and produces a peculiareffect on the nerves of the tongue, inasmuch as the point ofcontact becomes deadened and very nearly insensitive. Itmelts at 98 degrees and solidifies again as crystals. Athigher temperature most of it decomposes with the formationof ammoniacal products, only a small amount appearing toescape unchanged. When heated on platinum foil it burnswith a brilliant flame, leaving no residue.Cocaine neutralizes acids completely; most of its saltsappear to remain amorphous and to crystallize only withdifficulty. The hydrochloric acid salt is the one thatcrystallizes most readily; it forms with a strong evolutionof heat when one treats cocaine with dry hydrochloric acidgas.Although cocaine bears considerable similarity toatropine in reality it does differ, as has been shownby comparing their reactions and and their provisionalformulas. Their similarity extends to the similarity oftheir gold chloride salts, both of which are precipitated as