Topical Management of arterial and venous ulcers - VascularWeb

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Exudate ManagementWound Fluid– Acute stimulates cell proliferation– Chronic - contributes to delayed healing• increased levels of MMP’s whichdegrades the extracellular matrix• selectively inhibits proliferating cells
Demonstrated effects of chronicwound fluid• Inhibits migration of fibroblasts• Inhibits division and proliferation offibroblasts and epithelial cells• Contains proteases that break downextracellular matrix proteins
Page 1 and 2: Professor of Surgery Chief, Divisio
Page 3 and 4: DisclosuresScientific Consultant•
Page 6 and 7: Venous/lymphatic ulcer• Common as
Page 8 and 9: • May be inatypicallocations• T
Page 10: Causes of Atypical WoundsInfectious
Page 13 and 14: When to biopsy a• Long durationch
Page 15 and 16: Rx protocol for VLU• Compression
Page 17 and 18: Coexistent arterial insufficiency:H
Page 19 and 20: Topical therapy• Wound debridemen
Page 21 and 22: Special considerations forpatients
Page 23 and 24: How much to debride?
Page 25 and 26: The necrotic toe
Page 27 and 28: Wound bacterial load• Bacterial c
Page 29 and 30: Biofilm/bacterial burden
Page 31 and 32: Wound bacteria data - chronicVLU•
Page 33 and 34: Vulcan trial• Michaels et al Br J
Page 35: What to put on the wound?• Over 5
Page 39 and 40: Exudate Management:DressingsNone Lo
Page 41 and 42: Hydrocolloids• Provide barrier if
Page 43 and 44: Foams, Specialty absorbents• High
Page 45 and 46: Negative pressure compared tomoist

Topical Management of arterial and venous ulcers - VascularWeb

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