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Formation of the active eukaryotic transcriptioninitiation complex (Part 2)4. TFIIE and TFIIF associatewith RNA polymerase II.5. RNA polymerase II ispositioned by TFIIB, and itscarboxy-terminal domainis bound by TFIID.6. The CTD is phosphorylatedby TFIIH and is releasedby TFIID; RNA polymeraseII can now transcribemRNA.
Transcription factor DNA-binding domain recognize DNA ofenhancer or promoterregion Trans-activating domain Interact with RNApolymerase Protein interactiondomain Modulate activity
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