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Roles of differential RNA processing duringdevelopment• mRNA should be in the cytoplasm to be translated --- RNA selection• Introns should be removed to be the mRNA --- RNA splicing
Regulation of ectoderm-specific gene expressionby RNA processingRegular HistologyRNA protection assayIn situ hybridizationwith exon probeOnly ectoderm expressed CyIIIamRNA, whereas endo/mesodermexpressed it as nRNA.
Page 3 and 4: An integrated account of gene expre
Page 9 and 10: Nucleosome and chromatin structureC
Page 11 and 12: Inactivation of a single X chromoso
Page 13 and 14: X chromosome inactivation in mammal
Page 15 and 16: Chromatin decompactionMechanical an
Page 17 and 18: Methylation of globin genes in huma
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Page 21 and 22: Insulators on folate/-globin genesp
Page 23 and 24: Basic anatomy of the genePromoter r
Page 25 and 26: Formation of the active eukaryotic
Page 27 and 28: Transcription factor DNA-binding do
Page 29 and 30: Summary of the steps involved in th
Page 31: Coupled transcription and mRNA proc
Page 35 and 36: Alternative RNA splicing FgfR2 & Bc
Page 37 and 38: 5.39 An integrated account of gene
Page 39 and 40: Differential mRNA longevity The lon
Page 41 and 42: Control of gene expression at the l
Page 43 and 44: Translational regulation in oocytes
Page 45 and 46: Current model for the formation and
Page 47 and 48: The dsRNA-mediated gene silencing p
Page 49: Next Class on Sep-15 Chapter 7, Fer

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