Serum proteins

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• Alpha-1 globulin. The protein portion of high-densitylipoprotein (HDL), the “good” type of cholesterol, isincluded in this fraction.• Alpha-2 globulin. A protein called haptoglobin, that bindswith hemoglobin, is included in the alpha-2 globulinfraction.• Beta globulin. In addition to carrying substances throughthe bloodstream, beta globulin <strong>proteins</strong> help fightinfection.• Gamma globulin. This <strong>proteins</strong> is important in preventingand fighting infectionSome gamma globulins bind to foreign substances (suchas virus or bacteria) and destroying them by the immunesystem
High Globulin Levels caused by:1. Chronic inflammatory diseases (ex: TB, Syphilis)2. Bone marrow disorders like multiple myeloma3. Leukemias4. Autoimmunity (Systemic lupus, collagen diseases)5. Rheumatoid arthritis6. Liver disease (biliary cirrhosis, obstructive jaundice)7. Carcinoid syndrome8. Ulcerative colitis9. Kidney disease (Nephrosis)10.Chronic infections (parasites, some cases of viral and bacterialinfection like viral hepatitis or HIV)
Page 1 and 2: Serum proteins
Page 3 and 4: ALBUMIN• Is the most abundant pro
Page 5 and 6: PathologyLow blood albumin levels (
Page 7 and 8: How we do albumin analysis?• Add
Page 9: Globulin Can be separated into diff
Page 13 and 14: MEASUREMENT OF PROTEINFRACTIONS•
Page 15 and 16: Serum protein electrophoresis• Th
Page 17: How does it work?• Blood must fir

Serum proteins

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