Serum proteins

UltracentrifugationPhysical Techniques• 1.Ultracentrifugation (analytical or Sedimentationvelocity ultracentrifuge) at 60,000 round per.min.• The boundary between the solvent and the protein isvisualized by an optical system –called (SehlierenSystem).Advantage• Most useful for the determination of the mol. wt ofproteinsDisadvantage• High cost of each analysis and poor resolving capacity(when applied to whole serum or plasma)