Biotechnology - Department of Chemical Engineering

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20OrganismsOrganism Pros ConsBacteria Fast growth ProcaryotesLow cost substratesLimited biosynthesisYeast Eucaryotes Limited excretionFilamentous fungiAdvancedbiosynthesisGood proteinexcretionComplex morphologyHigh viscosity media
Product Organism UseIndustrial enzymesLipasesProteasesCellulasesPectinasesBeer, wineFilamentous fungi e.g.Aspergillus spp.Trichoderma spp.Bacteria e.g. BacillusSaccharomyces cerevisiae(yeast)DetergentsFood IndustryFood IndustryEthanol Saccharomyces cerevisiae Fuel, chemicalCitric acid Aspergillus niger Food Industry,Amino acidsPhenylalanineLysineGlutamic acidEscherichia coliCorynebacterium glutamicumFeed and FoodThe sweetener aspartam ismade from phenylalanineand aspartic acid1,3 propandiol Escherichia coli One of the monomers forproudction of Sorona TM(DuPont)Lactic acidAntibioticsPenicillinCephalosporinStreptomycinStatinesTherapeutic proteinsInsulinTillväxthormonLactobacilli and other bacteria butalso yeastsPenicillium chrysogenumAcremonium chrysogenumStreptococcusAspergillus terreusSaccharomyces cerevisiaeEscherichia coli21Food IndustryPolymerPharmaceuticalsStatines are used to controlblood levels of cholesterolPharma
Page 1 and 2: BiotechnologyLECTURE 15 - KETF20 CH
Page 3 and 4: Market outlook3
Page 5 and 6: Approximate price ($/kg)5Market out
Page 7 and 8: 7Biotechnical processesFeedstockEnz
Page 9 and 10: 9Fermentation processes• Food ind
Page 11 and 12: Conversion processes• Cells need
Page 13 and 14: 13Biotechnology characteristics•
Page 15 and 16: 15A brief history of biotechnology
Page 17 and 18: 17A brief history of biotechnologyA
Page 19: 19Organisms• Organisms in industr
Page 23 and 24: 23OrganismsAspergillus niger
Page 25 and 26: 25BioreactorsFoambreakerMotorOff-ga
Page 27 and 28: 27Bioreactors• Lab scale- 0.5 - 1
Page 29 and 30: 29BioreactorsLab scale bioreactor
Page 31 and 32: BioreactorsIndustrial full scale bi
Page 33 and 34: 33Process typesProcess type Pros Co
Page 35 and 36: 35Process types• Gas-liquid-phase
Page 37 and 38: 37Process typesReactor type k l a l
Page 39 and 40: 39Sterilisation• Eliminate contam
Page 41 and 42: 41Sterilisation• Separate sterili
Page 43 and 44: YeastProduction of baker’s yeast.
Page 45 and 46: YeastAmmoniaDefoamerNutrientsVentBe
Page 47 and 48: 47Ethanol1st generationSugar and st
Page 49 and 50: 49Ethanol in SwedenAgroetanol in No
Page 51 and 52: 512 nd generation ethanol• Differ
Page 53 and 54: 532 nd generation ethanol• How mu
Page 55 and 56: 55Sweeteners• Production of high
Page 57 and 58: Sweeteners• for enzyme• for pH
Page 59 and 60: 59PenicillinThe penicillin structur
Page 61 and 62: 61PenicillinProduction of semisynth
Page 63 and 64: 63Insulin• Growing number of diab
Page 65 and 66: InsulinProcess flow diagram for ins
Page 67 and 68: 67Entering the market• Lactic aci
Page 69: 69Concluding remarks• Current imp

Biotechnology - Department of Chemical Engineering

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