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Descriptive Psychopathology: The Signs and Symptoms of ...

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100 Section 2: <strong>The</strong> neuropsychiatric evaluation<strong>The</strong> episodes, however, always began with him suddenly experiencing asense <strong>of</strong> impending doom with physiologic signs <strong>of</strong> anxiety, followed by seeinga frightening, shadowy figure <strong>of</strong>f in the distance. After several <strong>of</strong> these experiencesa psychotic episode emerged. Of late, the small distant figure began toapproach him, becoming larger <strong>and</strong> more ominous. When finally st<strong>and</strong>ingnext to the patient, the figure was literally felt to be trying to enter thepatient’s body to “control” him. <strong>The</strong> patient concluded the “demon” wantedto assume his identity <strong>and</strong> that his only recourse was to let the demon enterhis body <strong>and</strong> then shoot it. He did not think he would also die.Recognized as experiencing classical signs <strong>of</strong> epilepsy (the patient hadsustained a serious head injury several years before his first psychotic episode<strong>and</strong> before that was a high-functioning, stable person), the patient was treatedwith an anticonvulsant (a seizure disorder was confirmed on EEG), made a fullrecovery <strong>and</strong> remained well.Pattern <strong>of</strong> symptomsPresent classification uses lists <strong>of</strong> unweighted symptoms as diagnostic criteria. If apatient has a certain number <strong>of</strong> features the threshold for illness is met, regardless<strong>of</strong> which features are present. A hypothetical example follows:A patient is observed to have a gr<strong>and</strong>iose delusion. He also meets the DSM catatonia criteria(two features are required) because he has excessive motor activity that is “apparently purposeless<strong>and</strong> not influenced by external stimuli”, <strong>and</strong> “echolalia <strong>and</strong> echopraxia”. Because he hasboth a delusion <strong>and</strong> catatonia he technically meets criteria for schizophrenia. Few experiencedclinicians, however, would consider this patient to be schizophrenic <strong>and</strong> many would diagnosemania because <strong>of</strong> the pattern <strong>of</strong> features.<strong>The</strong> pattern <strong>of</strong> features influences differential diagnosis. <strong>The</strong> pattern <strong>of</strong> psychopathology<strong>of</strong> Patient 1.1, the man who suffered carbon monoxide poisoning,was consistent with a frontal lobe syndrome, not depressive illness. <strong>The</strong> pattern <strong>of</strong>features in Patient 1.4, the woman with Capgras syndrome, was consistent with aright cerebral hemisphere stroke. <strong>The</strong> pattern <strong>of</strong> psychomotor disturbance (agitationor slowing), non-reactive apprehensive <strong>and</strong> gloomy mood, <strong>and</strong> vegetativedisturbances (poor sleep, poor appetite, no libido), <strong>and</strong> evidence <strong>of</strong> circadianrhythm disturbances (night sweats, tachycardia) defines melancholia. 21Primacy <strong>of</strong> featuresFor the most part, present classification does not assign special diagnostic significanceto any single feature, recognizing that there are no pathognomonic signsin psychiatric classification. An exception is in the criteria for psychotic disordersin which one feature is sufficient to secure the diagnosis <strong>of</strong> schizophrenia if it is a

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