September 2007 - Wadsworth Center

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A failure to attain an overall score of 80% is considered unsatisfactory performance. Laboratoriesreceiving unsatisfactory scores two out of three consecutive proficiency test events may be subject to ‘ceasetesting’ of clinical specimens.*The use of brand and/or trade names in this report does not constitute an endorsement of the products on thepart of the <strong>Wadsworth</strong> <strong>Center</strong> or the New York State Department of Health.6
ANSWER KEYMycology – GeneralSpecimen Key Validated Specimen Other Acceptable AnswersM-1 Malbranchea sp. Not validatedM-2 Acremonium sp. Acremonium sp.M-3 Chrysosporium sp. Chrysosporium sp.M-4 Fusarium sp. Fusarium sp. Fusarium oxysporumFusarium solaniM-5 Penicillium sp. Penicillium sp.M-Edu. Trichothecium sp. Trichothecium roseumMycology – Yeast OnlySpecimen Key Validated Specimen Other Acceptable AnswersY-1 Candida dubliniensis Candida dubliniensisY-2 Rhodotorula minuta Rhodotorula minutaY-3 Candida viswanathii Not validatedY-4 Candida parapsilosis Candida parapsilosisY-5 Trichosporon asahii Trichosporon asahiiMycology – Antifungal Susceptibility Testing for Yeasts (S-1: Candida albicans)DrugsValidated range (μg/ml)5-fluorocytosine 0.125 – 2.0Amphotericin B 0.06 – 2.0Caspofungin 0.015 – 1.0Fluconazole 0.06 – 4.0Itraconazole ≤ 0.015 – 0.5Ketoconzole ≤ 0.25Posaconazole ≤ 0.125Voriconazole ≤ 0.125Mycology – Direct detection (Cryptococcus Antigen Test)Specimen Key Validated Specimen Other Acceptable Titer RangeCn-Ag-1 Negative NegativeCn-Ag-2 Positive (1:16) Positive (1:16) 1:4 – 1:64Cn-Ag-3 Negative NegativeCn-Ag-4 Positive (1:128) Positive (1:128) 1:32 – 1:512Cn-Ag-5 Negative NegativeCn-Ag-Edu Positive (1:128) 1:32 – 1:5127
Page 3 and 4: CONTENTSContents 3Schedules 4Test S
Page 8 and 9: LABORATORY PERFORMANCE SUMMARYMycol
Page 10 and 11: MOLD DESCRIPTIONSM-1 Malbranchea sp
Page 12 and 13: 3. Kaufman, L., Standard, P.G., Hup
Page 14 and 15: A. B.Figure 1. (A) One-week-old col
Page 16 and 17: Query 121 GTCCGCCGGGGAAAACCAAACCCTG
Page 18 and 19: A. B.Figure 3. (A) Seven-day-old, p
Page 20 and 21: ectangular, of the same diameter as
Page 22 and 23: TABLE 2: Differentiation of Chrysos
Page 24 and 25: M-4 Fusarium sp.Source: NailsScorin
Page 26 and 27: A. B.Figure 7. (L) Seven-day-old, w
Page 28 and 29: A. B.Figure 9. (A) Seven-day-old, w
Page 30 and 31: Query 180 TTGGTTCTGGCATCGATGAAGAACG
Page 32 and 33: YEAST DESCRIPTIONSY-1 Candida dubli
Page 34 and 35: Alignment of primary sequence of th
Page 36 and 37: Y-2 Rhodotorula minutaSource: Cathe
Page 38 and 39: Figure 15. Seven-day-old, soft, smo
Page 40 and 41: Sequences alignment:Query 1 TCCGTAG
Page 42 and 43: Y-4 Candida parapsilosisSource: Sto
Page 44 and 45: 8. Yalaz, M., Akisu, M., Hilmioglu,
Page 46 and 47: Y-5 Trichosporon asahiiSource: Bloo
Page 48 and 49: 5. Panagopoulou, P., Evdoridou, J.,
Page 50 and 51: ANTIFUNGAL SUSCEPTIBILITY TESTINGIn
Page 52 and 53: DIRECT DETECTION (CRYPTOCOCCUS NEOF
Page 54 and 55: Table 4. Summary of quantitative as
Page 56 and 57:
25. Rebell, G. and Taplin, D. 1972.
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September 2007 - Wadsworth Center

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