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Uncertainty of the iodine-131 ingestion dose conversion factor

Uncertainty of the iodine-131 ingestion dose conversion factor

Uncertainty of the iodine-131 ingestion dose conversion factor

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Sample calculations <strong>of</strong> <strong>the</strong> roots and integration constants where performed using <strong>the</strong>following values for <strong>the</strong> rate constants:ln( 2)ln( 2)ln( 2) ln( 2)λ = k = k = k =802 . d 025 . d 120 d 12 dbl t b(23)with f 1= 1.0, f blt= 0.3, f bbl= 0.9, and S = 1 Bq <strong>of</strong> <strong>131</strong> I ingested. With <strong>the</strong>se inputs, <strong>the</strong> roots andintegration constants were determined. A high degree <strong>of</strong> precision was necessary during <strong>the</strong>numerical calculation <strong>of</strong> <strong>the</strong>se values due to <strong>the</strong> large difference in <strong>the</strong> magnitudes <strong>of</strong> <strong>the</strong> three rootsas well as taking powers <strong>of</strong> <strong>the</strong> roots in eqn (22). The final solutions for <strong>the</strong> time-dependent <strong>iodine</strong>activity in <strong>the</strong> three compartments can be presented at a lower precision. For <strong>the</strong> base case givenhere, <strong>the</strong> <strong>iodine</strong> activity in each compartment as a function <strong>of</strong> time, t, can be expressed as,−2. 86t −0. 146t −0.tXt () = 1. 00e − 0. 000613e + 0.000588e0905 Bq , (24)−2. 86t −0. 146t −0.tYt () =−0. 301e − 0. 00949e + 0.291e0905 Bq , and (25)−2. 86t −0. 146t −0.tZt () = 0. 000640e − 0. 0320e + 0.0313e0905 Bq. (26)The activity <strong>of</strong> o<strong>the</strong>r isotopes <strong>of</strong> radio<strong>iodine</strong> in <strong>the</strong> various compartments as a function <strong>of</strong> time canbe calculated ra<strong>the</strong>r easily by multiplying eqns (24) - (26) by <strong>the</strong> <strong>factor</strong>,−( i − . ) teλ 0 0862 , (27)where λ iis <strong>the</strong> decay constant (in units <strong>of</strong> d -1 ) <strong>of</strong> <strong>the</strong> radio<strong>iodine</strong> in question. The integrated activityin each compartment after <strong>ingestion</strong> to a time T, in units <strong>of</strong> d, is determined using,10

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