Understanding and Treating Bipolar Disorder - Free CE
Understanding and Treating Bipolar Disorder - Free CE
Understanding and Treating Bipolar Disorder - Free CE
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Page 12<strong>Underst<strong>and</strong>ing</strong> <strong>and</strong> <strong>Treating</strong> <strong>Bipolar</strong> <strong>Disorder</strong>© 2012 Pharmaceutical Education Consultants, Inc. unless otherwise noted. All rights reserved.Reproduction in whole or in part without permission is prohibited.Level TIMA EXC APA CANMATFirst-lineVPA,ARI, RISP,ZIPAlt: OLAN,CBZSecond-line Combo of 2:Li, VPA, SGAVPACombo:Mood stab. +SGACombo:Li orVPA + SGAAdd anotherMood stab.,OXC, switchSGALi, VPA,OLAN, RISP,QTP, ARI, ZIP,Li or VPA +SGACBZ, ECT,Li + VPA,AsenapineLi or VPA +asenapine orpaliperidoneLi – Lithium; VPA – Valproic Acid; SGA – Second generation antipsychotic; CBZ – carbamazepine; RISP–risperidone; OLAN – olanzapine; QTP – quetiapine; ARI – aripiprazole; ZIP – ziprasidone; OXC – oxcarbazepine;ECT – electroconvulsive therapy;• Mood stabilizer treatment is long-term <strong>and</strong> considered to bemaintenance treatment to reduce time to subsequent moodepisodes• Treatment is limited by tolerability to medications <strong>and</strong> medicationadherence• Adherence can be affected by– Adverse effects– Loss of pleasurable effects of mania– Poor motivation during depression– Lack of insight into the need for treatment• Suicide attempt risks are high in both poles of the illness – mustmonitor closelyPharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.• <strong>Bipolar</strong> disorder is a chronic mental disorder disease marked byrecurrent mood episodes of depression, hypomania, <strong>and</strong>/or mania• The causes are multifactorial, including genetics, psychosocial,traumatic, <strong>and</strong> neurophysiologic• Mood stabilizers, including lithium <strong>and</strong> anticonvulsants, as well assecond-generation antipsychotics are the mainstays ofpharmacological treatment• Health care professionals must promote adherence by designingdrug regimens to minimize adverse effects <strong>and</strong> educating patients<strong>and</strong> families on the consequences of untreated illness.PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.
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