Understanding and Treating Bipolar Disorder - Free CE

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Page 1Understanding and Treating Bipolar Disorder© 2012 Pharmaceutical Education Consultants, Inc. unless otherwise noted. All rights reserved.Reproduction in whole or in part without permission is prohibited.Understanding and Treating Bipolar DisorderAccreditationFacultyPharmacists: 0798-0000-12-068-L01-PPharmacy Technicians: 0798-0000-13-068-L01-TJason NoelNurses: N-790PharmD, BCPPAssociate ProfessorUniversity of Maryland School of PharmacyCE Credit(s)Faculty Disclosure1.25 contact hour(s)Dr. Noel has no actual or potential conflicts of interest inrelation to this program.Learning Objectives• Review the epidemiology, etiology, and pathophysiology of bipolar disorder• Describe current and emerging pharmacological approaches for the management of bipolar disorder to includeefficacy, safety, and roles of available treatments• Review the pharmacist’s role in counseling patients on the lifestyle changes, drug treatment strategies and medicationadherence to improve the quality of life and long-term maintenance of bipolar patientsLegal DisclaimerThe material presented here does not necessarily reflect the views of Pharmaceutical Education Consultants (PharmCon) or the companies thatsupport educational programming. A qualified healthcare professional should always be consulted before using any therapeutic product discussed.Participants should verify all information and data before treating patients or employing any therapies described in this educational activity.This activity is supportedby an 2/20/2013 educational grant1from Sunovion Pharmaceuticals, Inc.This activity is supportedby an 2/20/2013 educational grant2from Sunovion Pharmaceuticals, Inc.• Review the epidemiology, etiology, andpathophysiology of bipolar disorder.• Describe current and emerging pharmacologicalapproaches for the management of bipolardisorder to include efficacy, safety, and roles ofavailable treatments.• Review the pharmacist’s role in counselingpatients on the lifestyle changes, drug treatmentstrategies and medication adherence to improvethe quality of life and long-term maintenance ofbipolar patients.• Ancient Greeks and Romans recognized the existence of“mania” and “melancholia” in affected individuals– Used waters from northern Italian spas for euphoric patients– Aristotle recognized the creative contributions of these peopleto art and science during this time• 1600s-1800s: European scholars identified bipolardisorder as an illness– Bonet (Switzerland, 1686) – named “manico-melancolicus”– Falret (France, 1850s) – identified a circular insanity separatedby euthymic intervals (manic-depressive psychosis)PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.
Page 2Understanding and Treating Bipolar Disorder© 2012 Pharmaceutical Education Consultants, Inc. unless otherwise noted. All rights reserved.Reproduction in whole or in part without permission is prohibited.• In early 1900s, biological theories became prominent– German psychiatrist Emil Kraepelin postulated that specificpathology was responsible for mental illnesses. Coined term“manic-depression”• Australian physician John Cade reports on the benefits oflithium salts in animals studies published in 1949• 1980 – Diagnostic and Statistical Manual of MentalDisorders, 3 rd edition establishes criteria for “BipolarDisorder”• One or more Manic or Mixed episodes– Drug-induced conditions or other psychiatricdiagnoses ruled out• Individuals most often have multiple MajorDepressive episodes throughout their life span• Usually a recurrent disorder with shifts in polarityobserved over timeAmerican Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders (4th ed. text revision)PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.• Abnormally and persistently elevated, expansive or irritable mood• Duration of at least one week (unless hospitalized)• ≥3 of the following (≥4 if mood is irritable)– Inflated self-esteem or grandiosity– Decreased need for sleep– Hyperverbal or pressured speech– Flight of ideas or racing thoughts– Distractibility– Increase in goal-directed activities– Excessive involvement in high-risk pleasurable activities• Mood symptoms must cause marked social or occupationaldisturbances or necessitate hospitalization for safetyAmerican Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders (4th ed. text revision)• Abnormally depressed or irritable mood over at least 2 wk• 5 or more of:– Depressed mood– Diminished pleasure in activities– Change in > 5% of body weight– Insomnia or hypersomnia– Psychomotor agitation or retardation– Fatigue or loss of energy– Feelings of worthlessness or guilt– Diminished ability to think or concentrate– Recurrent thoughts of death/suicide• Causes distress or psychosocial impairmentAmerican Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders (4th ed. text revision)PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing education.
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