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High vs low dosing of oralColchicine for early acute gout flareR.A. Terkeltaub et. al. Arthritis andRheumatism 2010; 62: 1060-8• High-dose is 4.8mg over 6 hours• Low-dose is 1.8mg over 1 hour
• Responders in low-dose is 37.8% and32.7% in high-dose, and 15.5% inplacebo.• High-dose: 76.9% diarrhoea, 19.2%severe diarrhoea and 17.3% vomiting.• Low-dose: 23.0% diarrhoea and no severediarrhoea nor vomiting.
Page 1 and 2: Dr Daniel ChingRheumatology Therape
Page 3 and 4: Disclosures• Advisory Boards and
Page 5 and 6: Take Home Message 1:Ankylosing Spon
Page 7 and 8: If only two symptoms and …• 0 f
Page 9 and 10: NB: No blood tests in the alarmsign
Page 11 and 12: Prescription and comorbidityscreeni
Page 13 and 14: Opportunities for improvingmedicati
Page 15 and 16: Concise Report:Gout: an independent
Page 17 and 18: Delayed initiation of uratelowering
Page 19 and 20: Failure to document response toULT
Page 21 and 22: Failure to use gout flareprophylaxi
Page 24 and 25: • 2-hourly dosing of Colchicine t
Page 28 and 29: Conclusion:• Low-dose Colchicine
Page 30 and 31: Benzbromarone• A uricosuric agent
Page 32 and 33: Renewal• Treatment remains approp
Page 34: New treatments for gout:• Febuxos
Page 37 and 38: Choosing Wisely1. Don’t test ANA
Page 39 and 40: Methotrexate in low doses(weekly) i
Page 41 and 42: Consider getting into the habit ofw
Page 43 and 44: Recommendation for vaccinationsin r
Page 45: Pharmac criteria1. Patient has Rayn
Page 48 and 49: NumberRheumatological Diagnosis of
Page 50 and 51: S Kalke, B Dasgupta.The accuracy of
Page 52 and 53: Numbernoneone-ten11-fifteen16-2021-
Page 54 and 55: SE Gabriel et al.A&R 1997; 40: 1873
Page 56 and 57: NumberDuration of Prednisone Treatm
Page 58 and 59: Number1009080706050403020100Atypica
Page 60 and 61: CONCLUSIONS2. Methotrexate was effi
Page 63 and 64: Back up Slidesfor Gout
Page 65 and 66: Gout• A common debilitating arthr
Page 67 and 68: Epidemiology of Gout in WomenV. Bho
Page 69 and 70: Back up Slidesfor PMR/GCA
Page 71 and 72: Results• 183 referrals were ident
Page 73 and 74: % of Patients Referred for eachcond
Page 75: • V Kyle, B Hazleman. Ann Rheum D

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