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New treatments for gout:• Febuxostat (Adenuric), a new selective inhibitor ofxanthine oxidase. Efficacious in renal impairment withno significant relationship between renal function andurate-lowering efficacy. 80-120mg once daily orally.• Poly(ethylene) glycol-uricase (PEG-uricase) orPegloticase. IV 8mg (4-12mg) every two weeks.Effective in resolving tophi, so use in ‘debulking’ tophi inadvanced gout before switching to another agent formaintenance treatment. (Not available in NZ).
Page 1 and 2: Dr Daniel ChingRheumatology Therape
Page 3 and 4: Disclosures• Advisory Boards and
Page 5 and 6: Take Home Message 1:Ankylosing Spon
Page 7 and 8: If only two symptoms and …• 0 f
Page 9 and 10: NB: No blood tests in the alarmsign
Page 11 and 12: Prescription and comorbidityscreeni
Page 13 and 14: Opportunities for improvingmedicati
Page 15 and 16: Concise Report:Gout: an independent
Page 17 and 18: Delayed initiation of uratelowering
Page 19 and 20: Failure to document response toULT
Page 21 and 22: Failure to use gout flareprophylaxi
Page 24 and 25: • 2-hourly dosing of Colchicine t
Page 26 and 27: High vs low dosing of oralColchicin
Page 28 and 29: Conclusion:• Low-dose Colchicine
Page 30 and 31: Benzbromarone• A uricosuric agent
Page 32 and 33: Renewal• Treatment remains approp
Page 36 and 37: Antinuclear Antibody TestingApproxi
Page 38 and 39: Injection of Carpal TunnelSyndromeI
Page 40 and 41: Problems:• No data sheet in NZ sp
Page 42 and 43: Monitoring Blood Tests for DMARDsCo
Page 44 and 45: New treatment for Raynaud’sPhenom
Page 47 and 48: Audit of PolymyalgiaRheumatica and
Page 49 and 50: S Bahlas et al.Clin Rheumatol 2000;
Page 51 and 52: NumberDiagnosis of Patients referre
Page 53 and 54: V Kyle, B Hazleman.Ann Rheum Dis 19
Page 55 and 56: V Kyle, B Hazleman.Ann Rheum Dis 19
Page 57 and 58: JT Gran & G Myklebust.Rheum 2000; 3
Page 59 and 60: CONCLUSIONS1. All patients diagnose
Page 61: Mean Duration of SteroidTreatment
Page 64 and 65: Review:The modern managementof gout
Page 66 and 67: Possible Explanations1. Alarming ri
Page 68 and 69: Conclusions:1. Magnitude and rate o
Page 70 and 71: Method• Solo practice in Timaru H
Page 72 and 73: Number of PatientsReferredResults:T
Page 74 and 75: NumberDuration of Symptoms prior to

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