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FREE TRIAL Help your eligible patients get a1-month supply up to 20,000 IU* One-time offer.FreeTrialPfizerFactor.comSee your local hemophilia representative today to request a form.If you are unable to reach your representative, please try 888-999-2349.*Offer applies to patients covered by a private commercial insurance plan only.*Terms and conditions apply.• Clinical response to XYNTHA may vary. If bleeding isnot controlled with the recommended dose of factor,determine the plasma level and administer a dose ofXynThA sufficient to achieve clinical response. If thefactor level does not increase or there is no response,suspect an inhibitor and perform appropriate testing.• The most common adverse reaction in the safety andefficacy study is headache (24% of subjects) and in thesurgery study is fever (43% of subjects). Overall, themost common adverse reactions (≥5% of subjects) inclinical studies were headache, fever, nausea, vomiting,diarrhea, and weakness.• XYNTHA is an injectable medicine administered byintravenous (IV) infusion. Patients should be advisedthat local irritation may occur when infusing XynThAafter reconstitution in XynThA® SOlOFUSe®.Please see accompanying full Prescribing Information on next page.1. Kelley B, Jankowski M, Booth J. An improved manufacturing process for XynthA/ReFacto AF. Haemophilia. 2009;1-9.doi:10.1111/j.1365-2516.2009.02160.x. 2. XynthA ®SOLOFUSE ® Antihemophilic Factor (Recombinant), Plasma/Albumin-Free PrescribingInformation, Wyeth Pharmaceuticals Inc. 3. XynthA ® Antihemophilic Factor (Recombinant),Plasma/Albumin-Free Prescribing Information, Wyeth Pharmaceuticals Inc.*terms and conditions apply. your patients must be currently covered by a private[commercial] insurance plan. For questions about the XynthA trial Prescription Program,please call 1.800.710.1379 or write us at XynthA trial Prescription Program Administrator,MedVantx, PO Box 5736, Sioux Falls, SD 57117-5736 If your patients are not eligible forthe trial prescription program, they may find help accessing Pfizer medicines by contactingPfizer’s RSVP program at 1-888-327-RSVP (7787).Manufactured by Wyeth Pharmaceuticals Inc.Marketed by Pfizer Inc.RUS473303-01 © 2012 Pfizer Inc. All rights reserved. Printed in the USA/July 2012<strong>ASD</strong> <strong>Healthcare</strong> 43

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