Eritrean National List of Medicines (2010)

FOREWORDI am pleased to present the completely revised and updated 5 th editionof the Eritrean National List of Medicines (ENLM 5 th edition) to allhealth professionals in Eritrea. As medicines play a major role in theprovision of healthcare services, the selection of the appropriatemedicines required for the maintenance of an effective health systemis one of fundamental and dynamic activities of the Ministry ofHealth.The Eritrean National List of Medicines, which is a major componentof the Eritrean National Medicine Policy, has been an indispensableinstrument for promoting the rational use and cost effectiveprocurement of medicines. It has been a tool for proper control ofsupply resulting in a fairly equitable distribution and availability ofessential medicines throughout the country. This exemplary success isthe result of an extreme sense of commitment by most prescribers anddispensers through strict adherence to the list throughout theirpractices. Higher adherence is further the outcome of the activeparticipation of professionals both in the public and private sectorsduring the review and updating process. The Ministry of Health wasable to consistently regulate the adherence to the list of procuredmedicines, including medicines procured by purchase or by donationduring peace as well as crisis.Since the Revised Eritrean National List of Medicines (ENLM 5 thedition) is a comprehensive list of medicines that are believed toeffectively treat the main health problems occurring in our country,strict adherence to the list during prescribing, dispensing, procurementand production of medicines remains a mandatory requirement.Moreover, it is the standing policy of the Ministry of Health thatgeneric name is used in all medicine prescribing, ordering, labelingand dispensing.Eritrean National List of Medicines 2010 Page 1

Taking into account the changing therapeutic requirements nationallyand internationally, ENLM will be revised periodically and acontinuous feedback through suggestions and comments from allconcerned is essential.In conclusion, I would like to congratulate all the participants of theworkshop in general and the National Medicine Selecting Committeein particular for their excellent work. I sincerely hope that the updatedlist will advance the service to all the users, and be able to prove theeffectiveness of our National Drug PolicyAmna NurhusienMinister of HealthJune 2010Eritrean National List of Medicines 2010 Page 2

ContentFOREWORD......................................................................................... 1INTRODUCTION................................................................................. 8ACKNOWLEDGMENTS ................................................................... 10LIST OF WORKSHOP PARTICIPANTS .......................................... 12SUMMARY OF CHANGES............................................................... 19ABBREVIATIONS............................................................................. 23CLASSIFICATION OF LEVEL OF USES......................................... 25ERITREAN NATIONAL LIST OF MEDICINES .............................. 271. ANAESTHETICS ......................................................................... 271.1. General Anaesthetics .............................................................. 271.2 Local Anaesthetics................................................................. 271.3 Preoperative Medication......................................................... 282. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTI-INFLAMMATORY MEDICINES AND MEDICINES USED TOTREAT GOUT. ............................................................................. 292.1 Nonopioids ............................................................................. 292.2 Opioids ................................................................................... 293. ANTIALLERGIES & MEDICINES USED IN ANAPHYLAXIS 304. ANTIDOTES AND OTHER SUBSTANCES USED INPOISONINGS............................................................................... 304.1 General ................................................................................... 304.2 Specific................................................................................... 315. ANTIEPILEPTICS........................................................................ 326. ANTI-INFECTIVE MEDICINES................................................. 336.1 Anthelminthic Medicines........................................................ 336.1.1 Intestinal Anthelminthics........................................................ 336.1.2 Antifilarials............................................................................. 336.1.3 Antischistosomals................................................................... 336.2 Antibacterials.......................................................................... 336.2.1 Penicillins............................................................................... 336.2.2 Other Antibacterials................................................................ 356.2.3 Antileprosy Medicines............................................................ 366.2.4 Antituberculosis Medicines .................................................... 37Eritrean National List of Medicines 2010 Page 3

6.3 Antifungal Medicines ............................................................. 386.4 Antiprotozoal Medicines ........................................................ 386.4.1 Antiamoebic & Antigiardiasis Medicines............................... 386.4.2 Antileishmaniasis Medicines .................................................. 396.4.3 Antimalarial Medicines .......................................................... 396.4.4 Antipneumocytocis and Antitoxoplasmosis Medicines .......... 406.5 Antiviral Medicines ................................................................ 406.5.1 Herpes and cytomegalovirus infections .................................. 406.5.2 Antiretroviral Medicines......................................................... 416.5.2.1 Nucleoside Reverse Transcriptase Inhibitors ........................ 416.5.2.2 Non-Nucleoside Reverse Transcriptase Inhibitors................ 416.5.2.3 Protease Inhibitors ................................................................ 426.6 Insect Repellents..................................................................... 427. ANTIMIGRAINE MEDICINES................................................... 427.1 For Treatment of Acute Attack ............................................... 428. ANTINEOPLASTIC AND IMMUNOSUPPRESSIVEMEDICINES................................................................................. 438.1 Immunosuppressive Medicines............................................... 438.2 Cytotoxic Medicines............................................................... 438.3 Hormones and Antihormones ................................................. 449. ANTIPARKINSONISM MEDICINES......................................... 4410. MEDICINES AFFECTING THE BLOOD ................................... 4510.1 Antianaemia Medicines .......................................................... 4510.2 Anticoagulants and Antagonists ............................................. 4511. BLOOD PRODUCTS AND PLASMA SUBSTITUTES .............. 4611.1 Plasma Substitutes.................................................................. 4611.2 Plasma Fractions for Specific Uses......................................... 4612. CARDIOVASCULAR MEDICINES............................................ 4612.1 Antianginal Medicines............................................................ 4612.2 Antidysrhythmic Medicines.................................................... 4712.3 Antihypertensive Medicines ................................................... 4712.4 Cardiac Glycosides ................................................................. 4812.5 Medicines Used In Vascular Shock........................................ 4812.6 Antithrombotic Medicines...................................................... 48Eritrean National List of Medicines 2010 Page 4

12.7 Lipid-lowering medicines....................................................... 4813. DERMATOLOGICAL MEDICINES ........................................... 4813.1 Antifungal Medicines (Topical).............................................. 4813.2 Anti-Infective Medicines ........................................................ 4913.3 Anti-Inflammatory and Antipruritic Medicines ...................... 4913.4 Astringent Medicines.............................................................. 4913.5 Keratoplastic and Keratolytic Agents ..................................... 4913.6 Scabicides and Pediculicides.................................................. 4914. DIAGNOSTIC AGENTS .............................................................. 5014.1 Ophthalmic Medicines............................................................ 5014.2 Radiocontrast Media............................................................... 5015. DISINFECTANTS AND ANTISEPTICS..................................... 5116. DIURETICS.................................................................................. 5117. EAR NOSE AND THROAT PREPARATIONS.......................... 5217.1 Ear Preparations ..................................................................... 5217.2 Nose Preparations................................................................... 5218. GASTROINTESTINAL MEDICINES ......................................... 5218.1 Antacid and Other Antiulcer Medicines ................................. 5218.2 Antiemetic Medicines............................................................. 5318.3 Antihaemorrhoidal Medicines ................................................ 5418.4 Anti-Inflammatory Medicines................................................. 5418.5 Antispasmodic Medicines....................................................... 5418.6 Cathartic Medicines................................................................ 5418.7 Medicines Used In Diarrhoea ................................................. 5518.7.1 Antidiarrhoeal (Symptomatic) Medicines............................... 5519. HORMONES, OTHER ENDOCRINE MEDICINES ANDCONTRACEPTIVES.................................................................... 5519.1 Adrenal Hormones and Synthetic Substitutes......................... 5519.2 Androgens .............................................................................. 5619.3 Contraceptives ........................................................................ 5619.3.1 Hormonal Contraceptives ....................................................... 5619.3.2 Intrauterine Device ................................................................ 5619.3.3 Barrier Methods...................................................................... 5719.4 Estrogens ................................................................................ 57Eritrean National List of Medicines 2010 Page 5

19.5 Insulins and Other Antidiabetic Agents.................................. 5719.6 Ovulation Inducers ................................................................. 5819.7 Progestogens........................................................................... 5819.8 Thyroid Hormones and Antithyroid Medicines ...................... 5819.9 Medicines for Erectile Dysfunction ........................................ 5820. IMMUNOLOGICALS .................................................................. 5820.1 Diagnostic Agents................................................................... 5820.2 Sera and Immunoglobulins..................................................... 5920.3 Vaccines ................................................................................. 5920.3.1 For Universal Immunization................................................... 5920.3.2 For Specific Groups of Individuals........................................ 6021. MUSCLE RELAXANTS (PERIPHERAL) ANDCHOLINESTERASE INHIBITORS............................................ 6022. OPHTHALMOLOGICAL PREPARATIONS .............................. 6122.1 Anti-Infective Agents ............................................................. 6122.2 Anti-Inflammatory Agents...................................................... 6122.3 Local Anaesthetics.................................................................. 6222.4 Miotics and Antiglaucoma Medicines .................................... 6222.5 Mydriatics............................................................................... 6222.6 Miscellaneous Ophthalmic Preparations ................................ 6223. OXYTOCICS AND ANTIOXYTOCICS...................................... 6323.1 Oxytocics................................................................................ 6323.2 Antioxytocics.......................................................................... 6324. PERITONEAL DIALYSIS SOLUTION....................................... 6325. PSYCHOTHERAPEUTIC MEDICINES ..................................... 6426. MEDICINES ACTING ON THE RESPIRATORY TRACT ........ 6526.1 Antiasthmatic Medicines ........................................................ 6526.2 Antitussives ............................................................................ 6626.3 Respiratory stimulant and pulmonary surfactants ..................... 6626.4 Mucolytic medicines ................................................................. 6627. SOLUTIONS CORRECTING WATER, ELECTROLYTE ANDACID BASE DISTURBANCES ................................................... 6627.1 Oral Rehydration .................................................................... 6627.2 Parenteral................................................................................ 67Eritrean National List of Medicines 2010 Page 6

27.3 Miscellaneous......................................................................... 6728. VITAMINS AND MINERALS..................................................... 68Eritrean National List of Medicines 2010 Page 7

INTRODUCTIONThe Eritrean National List of Medicines (ENLM) is a list of medicineswhich defines the range of medicines that are available to importers,manufacturers, distributors, prescribers or dispensers in Eritrea. Italso defines the level of use of medicines in different health facilities.Its preparation is based on the treatment of choice for the mostcommon diseases and medical conditions in the country. Evidence ofefficacy, safety, cost, quality and availability were the main criteria forselection.The first edition, a successor of the Basic List of Medicines waspublished in 1988 during the struggle for independence, waspublished in 1993 after liberation and was widely circulated. A regularrevision is necessary because knowledge and ideas about medicinesare constantly changing, new drugs are coming to the market, andexperience with the existing medicines is continuously expanding.The subsequent 2 nd , 3 rd and 4 th editions were published in 1996, 2001and 2005 respectively. Drug use indicator surveys in 1995, 1997 and2005 showed more than 90% adherence to the list by healthprofessionals in Eritrea which shows a wide acceptance of theconcept.A selection in the Eritrean National Drug Policy states that: “TheEritrean National List of Medicines will be reviewed at least everythree years”. In 1998 National Drug Committee which is composed ofknowledgeable individuals from different health disciplines wasestablished. Main responsibility of the committee is to review ENLM,publish Eritrean Drug Formulary, Eritrean National TreatmentGuidelines as well as to overlook any drug related problems includingpharmacovigilance.As usual during the recent ENLM revision review forms weredistributed to health professionals in the country. The comments andsuggestions were compiled and formed the basis for discussion in anational workshop held at the Orotta National Referral HospitalConference hall from 30 June – 02 July 2009.Eritrean National List of Medicines 2010 Page 8

One hundred and fifteen participants selected from various disciplinesof the health profession, including health professionals from thepublic and private sectors and representatives of international agenciessuch as WHO & UN agency groups attended the workshop. A full listof the participants is shown on page 12. Considerable attention wasgiven to ensure wider representation and involvement of healthworkers. An experienced consultant Dr Richard Laing, WHO EDMprogram, Geneva was there for his third time in Eritrea to share expertopinion and to facilitate the workshop. The workshop was conductedunder an extreme sense of commitment and active interest of theparticipants. A summary of the consensus reached regarding changesto the previous list is given on page 19.ENLM 5 th edition will be revised after a period of three years, to thatend it shall supersede the previous 4 th edition. Adherence to the list inprocuring or prescribing drugs is a legal requirement. However, thelist is not set in stone and in exceptional cases application forpermission to obtain non-listed products could be considered by theNational Drug Committee on condition that the request has thesupport of the Department of Health Services.Seare GhebreyesusHead Pharmaceutical Information UnitMedicine Control DivisionDepartment of Regulatory ServicesEritrean National List of Medicines 2010 Page 9

ACKNOWLEDGMENTSThe Department of Regulatory Services would like to extend a specialthanks to all the National Drug Committee members who thoroughlysupervised the revision process of the ENLM. The department is alsograteful to all health professionals who sent their valuable commentsand suggestions; and to the consensus building workshop participantsfor their enthusiastic participation, without which the revision wouldnot have achieved success.We owe special thanks to WHO-Eritrea for its assistance in fundingthe workshop activities and printing of the Eritrean National List ofMedicines 5 th edition, as well as for sponsoring the consultant. Specialthanks goes to Dr. Idrisa Sow, WHO country representative and Headof Mission for his consistent encouragement and co-operation inpromoting the Essential Drugs Programme in Eritrea.We would also like to thank Dr. Richard Laing, professor, consultantfrom WHO EDM program, Geneva, for his remarkable contribution tothe success of the workshop:.Department of Regulatory ServicesMinistry of HealthEritrean National List of Medicines 2010 Page 10

National Drug Committee Members(NDC)Dr. Berhane Debru, Deputy Chair, NDC; Director, Division ofClinical Services, MOHMr. Embaye Andom, Pharmacist, Secretary of NDC; Director ofMonitoring & Evaluation Division, MOH,Dr Desbele Gebreghiorgis, Ophatalmologist Medical Director,Berhan Eye National Referral, HospitalMr. Frezghi Berhane, Chief Pharmacist, Kanzen Y. & SonsPharmaceutical sector,Dr. Kebreab Asrat, Gynecologist Medical Director, OrottaNational Referral Maternity Hospital,Dr. Michael Mehari, Pediatrician, Orotta National ReferralPediatric HospitalDr. Yemane Seyoum, Internist, Orotta School of MedicineMr. Yemane Zeremariam, Pharmacist, Sales Manager,PHARMECOR- EritreaEritrean National List of Medicines 2010 Page 11

List of Workshop ParticipantsSorted in alphabetical order1. Mr. Abraham Tesfaselasse, PHO, Head, Quarantine and PortHealth Unit, Department of Regulatory Services, MoH, Asmara2. Mr. Abraham Indrias, Pharmacist, Jaliya private pharmacy,Asmara3. Mr. Ali Omer, Pharmacist, President of ERIPA, Asmara4. Mr.Amanuel Abraha, Pharmacist, Halibet Referral Hospital,Asmara5. Dr. Andeberhan Tesfatsion, MD, Director, National AIDS andTB Control Division, MoH, Asmara6. Mr. Andebrihan Tewelde, Statistician, Monitoring andEvaluation Division, MoH, Department Of Regulatory Services,Asmara7. Dr. Araia Berhane, MD, Manager, HIV/AIDS Care and SupportUnit, NATCoD, MoH, Asmara8. Ms. Ariam Isak, Pharmacist, Assistant Instructor, AsmaraCollege of Health Sciences, Asmara9. Mr. Asmerom Beraki, Pharmacist, National Drug Quality ControlLaboratory, Department of Regulatory Services, MoH, Asmara10. Dr. Bereket Sebhatu, Gynacologist, Orotta Maternity Hospital,President of ERIMA, Asmara.11. Mr. Bereketab Tesfayesus, Pharmacist, Product RegistrationUnit, Department of Regulatory Services, MoH, Asmara12. Dr. Berhane Debru, MD, Director, Medical Services Division,Department of Health Services, MoH, Asmara13. Mr.Berhane Gebretinsae, Director General, Department of HealthServices, MoH, Asmara.14. Mr. Beyene Seiletsion, Pharmacist, Haddish Zemen Pharmacy,Representative of Retail Pharmacies, Asmara15. Dr. Beyene Tewelde, MD, Medical Director, Halibet ReferralHospital, AsmaraEritrean National List of Medicines 2010 Page 12

16. Dr. Dawit Estifanos, MD, Medical Director of Akordat Hospital,Akordat.17. Mr. Dawit Gebreyohannes, Pharmacist, Azel PharmaceuticalShare Company, Asmara.18. Mr. Desbele Berhe, Pharmacy Technician, PHARMECORE,Asmara.19. Dr. Desbele Ghebregherghis, Ophthalmologist, Medical Director,Berhan Eye National Referral Hospital, Asmara20. Mr. Elias Sibhatu, Pharmacist, St.Mary Neuro-psychiatricHospital ,Asmara21. Mr. Estifanos Hagos, Pharmacologist, Technical Manager,Gonafer22. Ms. Eva Johanson, unicef country representative23. Ms. Eyerusalem Beyene, Nurse/Midwives, RH Unit, MoH.24. Mr. Freminathos Misghina, Pharmacist, Head PharmaceuticalServices, Debub Zone, Mendefera.25. Mr. Frezghi Berhane, Pharmacist, Kanzen Yehia & Son HealthCare, Medicines and Supplies Importer, Asmara26. Dr.Gebremeskel Belay, MD, Haz-Haz Hospital, Asmara27. Mrs. Gedey Tesfai, Pharmacy Technician, NDQCL, Departmentof Regulatory Services, MoH, Asmara28. Mr. Gerezgiher Habte, Pharmacist, NDQCL, Department ofRegulatory Services, MoH, Asmara29. Dr. Ghenet Meresie, Ophthalmologists, Berhan Eye NationalReferral Hospital, Asmara30. Mrs. Ghidei Kiflai, Anesthetist, Halibet Hospital, Asmara31. Dr. Ghirmay Andemichael, KHP Advisor, WHO-Eritrea, Asmara32. Dr. Ghirmay Tesfaselase, MD, Head of InternationalCooperation, Office of Minister, Asmara33. Dr. Ghirmai Gebresilassie34. Mr. Giorgio Solomon , Pharmacist, Head, Narcotic andPsychotropic Substance Unit, Department of RegulatoryServices, MoH, AsmaraEritrean National List of Medicines 2010 Page 13

35. Dr. Goitom Hagos, Internist, Orotta National Referral Hospital,Asmara36. Dr. Goitom Mebrahtu, MD/PH, Director of DPC, Department ofHealth Services, MoH, Asmara37. Mr. Habtom Gebremichael, Pharmacist, Production Officer, AzelPharmaceutical Share Company, Keren.38. Dr. Habte Gebremichael, MD, Head of Research Unit,Department of HRD, MoH, Asmara.39. Dr. Habte Hailemelekot, Gynecologist, Mendefera RegionalReferral hospital, Mendefera.40. Dr. Habteab Mehari, MD, Head of Referral HospitalsCoordination Office, MoH, Asmara41. Mr. Hailemariam Andemariam, IDSR Surveillance Officer, MoH,Asmara.42. Mr. Henok Gebretinsae, Pharmacist, Assistant Instructor, AsmaraCollege of Health Sciences, Asmara43. Dr. Idrisa Sow, WHO Country Representative, Asmara.44. Mr. Ishii Nobuyuki JiCA, Asmara45. Mr. Ismalil Mohammed Feki, Nutrition Unit, MoH, Asmara46. Dr. Ismail Mohamed Jemal, Head CAH Unit, Department ofHealth Services, MoH, Asmara47. Mr. Iyasu Bahta, Pharmacist, Acting Director of Medicine andMedical Device Control Division, Department of RegulatoryServices MoH, Asmara48. Mr. Kahsay Berhane, Assab Regional Referral Hospital,Pharmacy Technician, Assab49. Dr. Kassey Negasi, MD, Medical Director, Dekemhare Hospital,Dekemhare50. Dr.Kesete Solomon, MD, Keren Regional Refferal Hospital,Keren.51. Dr. Kibreab Asrat, Gynecologist, Medical Director, OrottaMaternity Hospital, Asmara.52. Mr. Kifle Afewerki, Pharmacist, Head of NDQCL, Department ofRegulatory Services, MoH, AsmaraEritrean National List of Medicines 2010 Page 14

53. Dr. Letemihiret Mihretab, MD, Digsa Hospital, Digssa.54. Dr. Luis Manuel Calero, Orotta School of Medicine, Asmara.55. Miss. Lula Tesfay, Pharmacy Technician, Zonal PharmaceuticalServices Gash Barka Zone, Barentu.56. Mr. Mehari Ghebregiorghis, PHCS Coordinator, Maekel Zone,Asmara57. Mr. Melles Sium, Pharmacist, Director of NHL, Asmara.58. Mr. Meswaiti Teclezghi, Pharmacy Technician, Licensing andAccreditation Unit, Department of Regulatory Services, MoH,Asmara59. Mr. Michael Kidane, Pharmacist, Head of PharmaceuticalServices NRS Zone, Massawa60. Dr. Michael Gebrehiwot, MD, Advisor to the Minister MoH,Asmara61. Mr. Michael Ghirmai, Pharmacist, Chief Store KeeperPHARMECORE, Asmara62. Mr. Michael Gebremedhin, PHCS, International Medical Corps(IMC), Asmara63. Dr. Michael Mehari, Pediatrician, Orrota Pediatric Hospital,Asmara64. Dr. Mineab Sebhatu, MD, National TB Control Unit, MoH,Asmara.65. Mr. Misghina Tekeste, Pharmacist, Department of RegulatoryService, Drug Registration Unit, MoH, Asmara.66. Mr. Misghina Tekleab, Pharmacist, General Manager,PHARMECOR, Asmara67. Mr. Mohammed Ahmed Hilal, Pharmacist, Technical ManagerKarrar Hiddad Karrar, Asmara.68. Mr. Mulugeta Alemu, Pharmacist, Head of Pharmacy HalibetHospital, Asmara69. Mrs. Munira Ibrahim, Pharmacist, Technical ManagerInternational Group, Asmara70. Mr. Mussie Yemane, Pharmacist, Head of PharmaceuticalService Maekel Zone, AsmaraEritrean National List of Medicines 2010 Page 15

71. Mr. Nega Fesahaye, Pharmacist, Head of Pharmacy, OrottaNational Referral Hospital, Asmara72. Dr. Neguse Ogbe, ENT Specialist, Halibet Referral Hospital,Asmara73. Prof. M.Raouf Hamed Professor of Pharmacology and AssociateDean for Research and postgraduate studies74. Dr. Richard Laing, MD, EDM, WHO-Geneva75. Prof. Salwa A.Metaele, Pharmacologist, Asmara College ofHealth Sciences, Asmara.76. Mr. Samuel Berhe, Pharmacist, Pharmaceutical Information Unit,Department of Regulatory Services, MoH, Asmara77. Mr. Seare Ghebreyesus, Pharmacist, Head PharmaceuticalInformation Unit, Department of Regulatory Services, MoH,Asmara78. Mr. Sebhatu Beyene, PHC, CAH Unit MoH, Asmara.79. Ms. Selam Mihireteab, Biologist, NMCT, Asmara.80. Mr. Semere Berhe, Pharmacist, Store, PHARMECOR, Asmara81. Mr. Semere Gebregiorgis, Pharmacist, NPO/MPN,WHO, Asmara82. Ms. Senait Dawit, Pharmacist, Community Pharmacy, No.5,Asmara83. Ms. Senait Weldegebriel, Pharmacist, Karrar Hiddad Karrar,Asmara.84. Mr. Shewit Tsehaye, Pharmacist, Registration Officer AzelPharmaceutical Share Company, Keren.85. Dr. Shigeki Taniho, DDS, JICA Project MoH, Asmara.86. Ms. Shushan Kebedom, Pharmacist, Head of Pharmacy, BerhanEye National Referral Hospital Asmara.87. Dr. Simon Haile, ENT Specialist, Halibet Referral Hospital,Asmara88. Dr. Simon Kiiru, Psychiatrist, St.Mary Hospital, Asmara89. Mr. Solomon Nemariam, Registered Nurse, Head Nurse MassawaHospital, Massawa.90. Mr. Tariq A.Jellal, Chemist, Technical Manager, AzelPharmaceutical Share Company, KerenEritrean National List of Medicines 2010 Page 16

91. Mr. Teclamariam Amare, Registered Nurse, Nursing Care UnitMoH, Asmara92. Mrs. Terhas Mehretab, Nurse, Director HR Training, MoH,Asmara93. Mr. Tesfaelase Ghedel, Pharmacist, Manager Chain Pharmacies,Asmara94. Dr. Tesfagaber Haile, Surgeon, Halibet Referral Hospital,Asmara95. Mr. Tesfaghiorgis Fessahaye, Pharmacy Technician, NDQCL,Department of Regulatory Services, MoH, Asmara96. Mr. Tesfalem Kudus, Pharmacist, Department of RegulatoryServices, Inspection Unit, MoH, Asmara.97. Mr. Tesfamariam Ngru98. Dr. Tesfay Solomon, MD, Director of Service Control andQuality Assurance, Department of Regulatory Services, MoH,Asmara99. Dr. Tewolde Gebremeskel, MD, Manager, Malarial Control Unit,Department of Health Services, MoH, Asmara100. Dr. Tewoldemedhin Yohannes, Paediatrician, Orotta PaediatricHospital, Asmara.101. Sr. Tsega Gebremichael, MLT, Eritrean Catholic Secretariat,Asmara102. Mr. Yemane Haile, MPH, Director of Personnel Office,Department of Research and Human Resource Development,MoH, Asmara103. Mr. Yemane Zeremariam, Pharmacist, Sales and DistributionManager, PHARMECOR, Asmara104. Mrs. Yodit Hiruy, Public Health, UNICEF health officer, Asmara105. Mr. Yoel Yigzaw, Marketing, AZEL Pharmaceutical ShareCompany, Asmara.106. Dr. Yohannes Ghebrat, DPC officer, WHO/Asmara107. Mr. Yonas Andemariam, Pharmacy Technician, Head pharmacy,Ghindae Hospital, GhindaeEritrean National List of Medicines 2010 Page 17

108. Mr. Yonas Ghebrezhgi, Pharmacist, Head PharmaceuticalServices Anseba Zone, Keren109. Dr.Yonas Yohannes, MD, Orrota National Referral Hospital,Asmara110. Mr. Yonatan Gebrehiwet, Marketing, AZEL PharmaceuticalShare Company, Asmara111. Dr. Zemichael Ogbey, Pediatrician, Medical Director, OrottaPediatric Hospital, Asmara112. Mr. Zemuy Ghirmay, Pharmacist, Product Registration Unit,Department of Regulatory Services, MoH, Asmara113. Mrs. Zewdi Sium, Nurse, MoH, AsmaraEritrean National List of Medicines 2010 Page 18

Summary of Changes1. Anesthetics1.2 Local AnaestheticsLidocaine hydrochloride is lowered from level 3 to level 1 due todelivery and incision at lower level (health station).- Injection, 1%, 2% in vial- Injection, 1%, 2% with epinephrine 1:200,000 in vial2. Analgesics, Antipyretics, NSAIDs and medicines used to treatgout2.1 NonopioidsPiroxicam - capsule, 20mg – deleted from the list due to the sideeffect.Naproxen - Tablet, 250,500mg – Added to the list at level three and isused to treat various painful conditions including postoperative painand the drug has long duration of action, high pain control score.Tramadol - Tablet, 50-200mg – Added to the list at level three and isused as an analgesic agent for the treatment of moderate to severepain.2.2 OpioidsPentazocine hydrochloride, 50mg tab, caps, 30mg/ml injection and 50mg suppositories – Deleted from the list due to the side effects.3. Antiallergies and medicines used in anaphylaxisCetrizine, 10mg Tablet and 5mg/5ml syrup – Added to the list at leveltwo and used for symptomatic relief of allergy such as hay fever,urticaria.6.2 Antibacterial6.2.4. Antituberculosis MedicineKanamycin, 1gm Vial, Ofloxacin, 400mg Tablet, Cycloserine, 250mgTablet, Ethionamide, 125mg, 250mg Tablet – Added to the list at levelEritrean National List of Medicines 2010 Page 19

three and these drugs are recommended for the treatment of multi -drug resistant TB (MDR-TB)6.4.3 Antimalarial MedicinesArtemether + lumefantrine, Tablet, 20mg + 120mg - Added to list atlevel three6.5.2 Antiretroviral MedicinesStavudine 40mg and all combinations which have Stavudine 40mgwere deleted from the list due to the side effect of stavudine 40mg thatis peripheral neuropathy.6.5.2.2 Non-Nucleoside Reverse Transcriptase InhibitorsTenofovir, Tablet, 300mg - Added to the list at level three.8. Antineoplastic and Immunosuppressive Medicines8.3 Hormones and AntihormonesDexamethasone , Oral liquid form as 2 mg/5 ml is added.Prednisolone, Oral liquid form as 5 mg/ml is added.12. Cardiovascular Medicines12.3 Antihypertensive MedicinesAmlodipine, Tablet, 5mg - Added to the list at level three and it isconvenient for geriatric use once daily.Enalapril, tablet, 2.5mg, tablet, 10mg strengths are added.12.7 Lipid-lowering medicinesAtorvastatin, Oral form as tablet, 10mg, 40mg(s) are added at level S.Simvastatin, Tablet, 10mg, 40mg - Added to the list at level three.Eritrean National List of Medicines 2010 Page 20

18. Gastrointestinal medicines18.1 Antacid and other Antiulcer MedicinesOmeprazole, Powder for oral liquid form as 20 mg, 40 mg sachets isadded.Ranitidine hydrochloride, as Oral liquid: 75 mg/5 ml is added.18.2 Antiemetic MedicinesMetoclopramide hydrochloride, Oral liquid form as syrup, 5mg/5ml isadded.18.7 Medicines Used In DiarrhoeaZinc sulphate, Oral liquid: in 10 mg per unit dosage forms and tablet:in 10 mg per unit dosage forms is added.19. Hormones, other Endocraine Medicines and Contraceptives19.5 Insulins and Other Antidiabetic AgentsGlimipride, Tablet, 1mg, 2mg, 3mg, and 4mg - Added to the list atlevel three and has extra pancreatic effect, long duration of action, itsmetabolite itself is active and has less risk of hypoglycemia.19.9 Medicines for erectile dysfunctionSildenafil, tablet, 25mg strength is added to the list at level three.22. OPHTHALMOLOGICAL PREPARATIONS22.1 Anti-Infective AgentsAzithromycin – Added to the list at level S and is used for masstreatment to control blindness due to trachomaDorzolamide + timolol, Drop, 2% + 0.5mg - Added to the list at levelS due to its additive effect in lowering intraocular pressure (IOP).Ciprofloxacin, Drop, 0.3% - Added to the list at level S andciprofloxacin eye drop can be used for corneal ulcers and it isextremely effective bactericidal drug with low corneal toxicity andrapid action.Eritrean National List of Medicines 2010 Page 21

Latonoprost, Drop, 0.005% - Added to the list at level S andlatonoprost is more effective in lowering pressure and has fewer sideeffects.This drug can be used for treatment of inoperable glaucomacases.23. OXYTOCICS and ANTIOXYTOCICS23.1 OxytocicsProstaglandin E 1 , Tablet, 25mcg, 200mcg (misoprostol) - Added to thelist at level three due to the oral effectiveness and its use for treatmentatonic PPH & induction labor and dinoprostone has been deleted.26. Medicines acting on the respiratory tractBromhexine, Tablet, 4mg, 8mg and Syrup, 5mg/5ml – added to the listat level three and this drug can be used as mucolytic agent and thisdrug enhance the penetration of antibiotics.27. Solutions correcting water, electrolyte and acid basedisturbances.Zinc, Tablet, 20mg added to the lsit28. Vitamins and mineralsIodine, Capsule: 200 mg.Riboflavin, Tablet: 5 mg.Eritrean National List of Medicines 2010 Page 22

ABBREVIATIONSmg = microgramDRS = Department of Regulatory ServicesENLM = Eritrean National List of Medicinesg = gramIM = Intramuscular injection (intramascularly)IU = International UnitIV = Intravenous injection (intravenously)mg = milligramml = millilitremm = millimetremmol = millimoleMOH = Ministry of HealthNDC = National Drug CommitteeNSAID = Non-steroidal anti-inflammatory medicinesORS = Oral Rehydration SaltsSC = Subcutaneous injection (subcutaneously)Eritrean National List of Medicines 2010 Page 23

CLASSIFICATION OF LEVEL OF USESThe following keys indicate classification of level of uses to beadhered to.1 = For use in all health care settings2 = For use in health centers and higher health care levels3 = For use in all hospitalsS = Specialty medicines; to be used in special cases and bekept only in the highest referral hospitalEritrean National List of Medicines 2010 Page 25

DrugLevelofUseDosage form and StrengthERITREAN NATIONAL LIST OF MEDICINESMedicine1. ANAESTHETICSLevelofUse1.1. General AnaestheticsDosage form and Strength1. Ether,anaesthetic 3 Inhalation2. Halothane 3 Inhalation3. Ketamine hydrochloride 3 Injection, 50mg/ml 10ml vial4. Oxygen 2 Inhalation5. Propofol S Injection, 10mg/ml, 20mg/mlin ampoule6. Soda Lime (CO 2 ) 2 Powder7. Thiopental sodium 3 powder for injection, 0.5g,1.0g in ampoule1.2 Local Anaesthetics1. Bupivacainehydrochloride33injection, 0.25%,0.5% in vialinjection for spinal anaesthesia0.5% in 4ml ampoule with7.5% glucose solutionEritrean National List of Medicines 2010 Page 27

LevelDrugofUseDosage form and Strength2. Lidocaine1 injection, 1%, 2% in vialhydrochloride1 injection, 1%, 2% withepinephrine 1:200,000 in vial3 injection for spinalanaesthesia 5% in 2mlampoule with 7.5% glucosesolution1 topical forms, 2-4 %3 dental cartridge, 2% +epinephrine 1:800003. Ethyl Chloride 1 topical forms, aerosol spray1.3 Preoperative Medication1. Atropine sulfate 3 injection, 1mg in 1ml ampoule2. Diazepam 3 injection, 5mg/ml 2mlampoule3. Midazolam S injection, 2mg/ml in 2ml,5mg/ml in 2ml ampoule4. Morphine hydrochloride 3 injection, 10mg in 1mlampoule5. Pethidine2 injection, 50mg in 1mlHydrocholorideampoule6. Promethazine2 elixir or syrup, 5mg/5mlhydrochloride7. Metoclopramide 3 injection, 5mg/ml in 2mlampoule8. Sodium citrate 3 oral solution, 490mg/5ml1.4 MiscellaneousKY Jelly 1Eritrean National List of Medicines 2010 Page 28

DrugLevelofUseDosage form and Strength2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTI-INFLAMMATORY MEDICINESAND MEDICINES USED TO TREAT GOUT.2.1 Nonopioids1. Acetylsalicylic acid 12tablet, 300mg, 500mgenteric coated tablet, 300mg2. Allopurinol 3 tablet, 100mg3. Colchicine 3 tablet, 500mg4. Ibuprofen 1 tablet, 200mg, 400mg5. Indomethacin 2 tablet or capsule, 25mg26. Diclofenac Sodium 22suppository, 100mgtablet, 25mg, 50mg (regularand/or modified release)suppository,12.5mg(paediatric) 100mginjection, 75mg/3ml ampoulegel 1%227. Paracetamol 1 tablet, 100-500mg1 suppository, 100mg1 syrup, 125mg/5ml8. Naproxen 3 Tablet, 250,500mg9. Tramadol 3 Tablet/capsule, 50mg -200mg2.2 Opioids1. Codeine phosphate 2 tablet, 30mg2. Morphine3hydrochloride33injection, 10mg in 1mlampouleoral solution 10mg/5mltablet,10mg (as sulfate)Eritrean National List of Medicines 2010 Page 29

LevelDrugofUse3. Pethidine hydrochloride 33Dosage form and Strengthtablet, 50mg, 100mginjection, 50mg/ml in 1mlampoule3. ANTIALLERGIES & MEDICINES USED INANAPHYLAXIS1.Chlorphenaminehydrogen maleate111tablet, 4mgsyrup, 2mg/5mlinjection, 10mg in 1mlampoule2. Cetrizine 3 Tablet,10mgSyrup,5mg/5ml3. Dexamethasone sodiumphosphate33tablet, 500mg, 4mginjection, 4mg4.Epinephrinehydrochloride1 Injection, 1mg in 1mlampoule5. Hydrocortisone sodiumsuccinate6. Prednisolone 3 tablet, 5mgOral liquid: 5 mg/ml2 powder for injection, 100mgin vial4. ANTIDOTES AND OTHER SUBSTANCES USEDIN POISONINGS4.1 General1. Charcoal, activated 11powdertabletEritrean National List of Medicines 2010 Page 30

LevelDrugofUseDosage form and Strength2. Ipecacuanha 2 syrup containing 0.14%ipecacuanha alkaloidscalculated as emetine4.2 Specific1. Atropine sulfate 2 injection, 1mg in 1mlampoule2. Deferoxamine mesilate 3 powder for injection, 500mgin vial3. Dimercaprol 3 injection in oil, 50mg/ml in2ml ampoule4. Methionine racemate 1 tablet 250mg5. Methylthioniniumchloride (methyleneblue)3 injection, 10mg/ml in 10mlampoule6. Naloxonehydrochloride3 injection, 400mg in 1mlampoule7. Penicillamine 3 capsule or tablet, 250mg8. Potassiumferrichexacyano ferrate(II), 2H 2 O (Prussian3 powderadministrationfor oralblue)9. Sodium calcium3 injection, 200mg/ml in 5mledetateampoule10. Sodium nitrite 3 injection, 30mg/ml in 10mlampoule11. Sodium thiosulfate 3 injection, 250mg/ml in 50mlampouleEritrean National List of Medicines 2010 Page 31

DrugLevelofUseDosage form and Strength5. ANTIEPILEPTICS1. Carbamazepine 3 tablet(scored), 100mg, 200mgtablet(chewable), 100mg,200mgoral liquid: 100 mg/5 ml2. Diazepam 2 injection, 5mg/ml in 2mlampoule (i.v or rectal)3. Ethosuximide 3 capsule or tablet, 250mg34. Phenobarbitone 22S5. Phenytoin sodium 36. Valproic acid 33syrup, 250mg/5mltablet, 15mg - 100mgelixir, 15mg/5mlinjection, 200mg/mlcapsule or tablet, 25mg, 50mg, 100mginjection, 50mg/ml in 5mlvialoral liquid: 25 mg to 30 mg/5ml.enteric coated tablet, 200mg,500mg (sodium salt)syrup, 200mg/5ml37. Clonazepam S tablet, 500mg8. Magnesium sulfate 3 injection, 500mg/ml in 2mlampouleEritrean National List of Medicines 2010 Page 32

DrugLevelofUseDosage form and Strength6. ANTI-INFECTIVE MEDICINES6.1 Anthelminthic Medicines6.1.1 Intestinal Anthelminthics1. Albendazole 22chewable tablet, 200mg,400mgoral suspension, 200mg/5ml2. Mebendazole 11chewable tablet, 100mgelixir, 100mg/5ml3. Niclosamide 1 chewable tablet, 500mg4. Praziquantel 2 tablet, 150mg, 600mg6.1.2 Antifilarials1.Diethylcarbamazine dihydrogencitrate3 tablet, 50mg2. Ivermectin 3 scored tablet, 3mg, 6mg6.1.3 Antischistosomals1. Praziquantel 2 tablet, 600mg6.2 Antibacterials6.2.1 Penicillins1.Amoxicillin(anhydrous)11capsule or tablet, 250mg,500mgpowder for oral suspension,125mg/5mlEritrean National List of Medicines 2010 Page 33

LevelDrugof Dosage form and StrengthUse2. Ampicillin sodium 3 powder for injection, 500mg,3.Benzathine benzylpenicillin1gm in vial1 powder for injection, 1.44g in5ml vial (2.4 million IU)720mg in 5ml vial(1.2million IU)4. Benzyl penicillin assodium or Potassiumsalt2 powder for injection, 600mg(= 1 million IU), 3g (= 5million IU), in vial5. Cloxacillin sodium 3 powder for injection, 500mg6. Flucloxacillin sodium 33in vialcapsule, 250mg, 500mgpowder for oral solution,125mg/5ml7.Phenoxymethylpencillin potassium11tablet, 250mgpowder for oral suspension,125mg/5ml, ]250mg/5ml8. Piperacillin sodium S powder for injection, 1g, 2g9.Procaine benzylpenicillin10. Ammoxicilin +Clavulanic acidin vial1 powder for injection,1g (= 1million IU),3g (= 3 million IU)Stablet, 250mg + 125mg,500mg + 125mgoral liquid: 125 mgamoxicillin + 31.25 mgclavulanic acid/5 ml and250 mg amoxicillin + 62.5 mgclavulanic acid/5 ml.Eritrean National List of Medicines 2010 Page 34

DrugLevelofUseDosage form and Strength6.2.2 Other Antibacterials1. Amikacin S injection, 50mg/ml,250mg/ml in 2ml vial2. Ceftazidime 3 powder for injection, 500mgin vial3. Ceftriaxone 3 powder for injection, 250mg,500mg, 1gm in vial4. Chloramphenicol 225. Ciprofloxacinhydrochloride33Scapsule, 250mgoral suspension, 150mg/5ml(as palmitate)powder for injection, 1g invial (as sodium succinate)oily suspension, 0.5g/2mlampoule (as sodiumsuccinate)tablet, 250mg, 500mgoral liquid: 250mg/5mlsolution for iv infusion:2mg/ml6. Clarithromycin S tablet, 250mgtablet, 500mg7. ClindamycinS injection, 150mg/mlphosphate8. Doxycycline hyclate 2 capsule or tablet, 50mg,100mgEritrean National List of Medicines 2010 Page 35

LevelDrugofUseDosage form and Strength9. Erythromycin 2 tablet or capsule, 250mg (asstearate or ethyl succinate)powder for oral suspension,2 125mg/5ml (as stearate orsuccinate)10. Gentamicin sulfate 3 injection 10mg/mlio,11. Metronidazole 133140mg/ml in 2ml vialtablet, 200-500mginjection, 500mg in 100mlvialsuppository, 500mg, 1goral suspension, 200mg/5ml(as benzoate)12. Nalidixic acid 3 tablet, 250mg, 500mg13. Nitrofurantoin 2 tablet, 50mg, 100mg14. Spectinomycinhydrochloride15. Sulfadiazine 3 tablet, 500mg16. Sulfamethoxazole + 1trimethoprim6.2.3 Antileprosy Medicines2 powder for injection 2g invial1tablet, 100mg + 20mg, 400mg+ 80mg, 800mg + 160mgoral suspension, 200mg +40mg/5ml1. Clofazimine 3 capsule, 50mg, 100mg2. Dapsone 3 tablet, 25mg, 50mg, 100mg,3. Rifampicin 3 capsule or tablet 100mg,300mgEritrean National List of Medicines 2010 Page 36

DrugLevelofUseDosage form and Strength6.2.4 Antituberculosis Medicines1. Ethambutolhydrochloride2. Isoniazid 222 tablet, 100 - 400mgoral liquid, 25 mg/mltablet, 100mg, 300mgoral solution, 50mg/5mltablet (scored), 50 mg3. Pyrazinamide 2 tablet, 400mg, 500mgoral liquid: 30 mg/mltablet (scored or dispersible)150 mg4. Rifampicin 222capsule or tablet, 150mg,300mgoral solution, 100mg/5mlpowder for i.v infusion,300mg in vial5. Streptomycin sulfate 2 powder for injection, 1g invial6. Rifampicin + Isoniazid 2 tablet, 30mg + 60mg,60mg+60mg, 75mg + 150mg,150mg + 150mg,7.Rifampicin+isoniazide+ pyrazinamide8. Isoniazide +ethambutol9. Isoniazide +rifampicin+pyrazinamide +ethambutol2 tablet, 30mg + 60mg + 150mg75mg +150mg + 400mg,2 tablet, 150mg + 400mg2 tablet, 75mg + 150mg +400mg + 275mgEritrean National List of Medicines 2010 Page 37

LevelDrugofUseDosage form and Strength10. Kanamycin s Vial, 1gm11. Ofloxacin s Tablet, 200 mg, 400mg12. Cycloserine s Tablet,250mg13. Ethionamide s Tablet,125mg,250mg6.3 Antifungal Medicines1. Amphotericin 3 powder for injection, 50mg invial2. Clotrimazole 1 vaginal tablet, 100mg, 500mg3. Fluconazole 333capsule, 50mg, 200mgoral suspension, 50mg/5mlinjection, 2mg/ml in vial4. Griseofulvin 2 capsule or tablet, 125mg,250mg, 500mgoral liquid, 125 mg/5 ml.5. Ketoconazole 336. Nystatin 116.4 Antiprotozoal Medicinestablet, 200mgoral suspension, 100mg/5mltablet, 500,000 IUpessary, 100,000 IU6.4.1 Antiamoebic & Antigiardiasis Medicines1.Diloxanide furoate 1 tablet, 500mg2. Metronidazole 131tablet, 200 - 500mginjection, 500mg in 100mlvialoral suspension, 200mg/5ml(as benzoate)3. Tinidazole 2 tablet, 500mgEritrean National List of Medicines 2010 Page 38

DrugLevelofUseDosage form and Strength6.4.2 Antileishmaniasis Medicines1. Meglumine antimonate 3 injection, 30% in 5mlampoule2. Pentamidine isetionate S powder for injection, 200mg,300mg in vial3. Sodium stibogluconate 3 injection, 100mg/ml6.4.3 Antimalarial Medicines(a) For Curative Treatment1. Amodiaquine 1 tablet, 153mg, 200mg(base)2. Artesunate 2 tablet, 50mg, 100mg3. Chloroquine 1 tablet, 100mg, 150mg (asphosphate or sulfate)1 syrup, 50mg/5ml (asphosphate or sulfate)1 injection, 40mg base/ml(ashydrochloride, phosphate orsulfate)4. Doxycycline 2 capsule or tablet,50mg,100mg5. Mefloquine 3 tablet, 250mg (ashydrochloride)6. Primaquine2 tablet, 7.5mg, 15mgdiphosphate7. Quinine 22tablet, 300mg (as sulfate orbisulfate)injection 300mg (asdihydrochloride) /ml in 2mlampouleEritrean National List of Medicines 2010 Page 39

Drug8. Sulfadoxine +Pyrimethamine9. Artemether +lumefantrine.(b) For Prophylaxis1. Chloroquine 1Levelof Dosage form and StrengthUse1 tablet 500mg + 25mg2 Tablet, 20mg + 120mg2. Proguanil hydrchloride 1 tablet, 100mg1tablet, 100mg, 150mg (asphosphate or sulfate)syrup, 50mg (as phosphate orsulfate) /5ml6.4.4 Antipneumocytocis and AntitoxoplasmosisMedicines1. Sulfamethoxazole +trimethoprim2. Pentamidine isetionate SS6.5 Antiviral MedicinesSStablet, 100mg + 20mg, 400mg+ 80mg, 800mg + 160mgoral suspension 200mg +40mg/5mltablet, 200mg, 300mgPowder for injection 200mg,300mg in vial6.5.1 Herpes and cytomegalovirus infections1. Aciclovir 333tablets, 200mg, 400mg,oral suspension, 200mg/5mlpowder for injection, 250mg(as sodium salt)Eritrean National List of Medicines 2010 Page 40

DrugLevelofUseDosage form and Strength6.5.2 Antiretroviral Medicines6.5.2.1 Nucleoside Reverse Transcriptase Inhibitors1. Abacavir 3 tablet, 300mgoral solution, 100mg/5ml2. Didanosine 333tablet, 25mg, 50mg, 100mg,200mgoral solution, 100mg/sachet,167mg/sachet,250mg/sachet,enteric-coated capsules,125mg; 200mg, 250mg,400mg3. Lamivudine 3 tablet, 150mgoral solution, 50mg/5ml4. Stavudine +Lamivudine3 tablet, Stavudine 30mg +Lamivudine 150mg;5. Stavudine 3 capsules, 15mg, 20mg, 30mg,oral solution, 5mg/5ml6. Zidovudine +Lamivudine3 tablet, Zidovudine 300mg +Lamivudine 150mg7. Zidovudine 3 tablet, 300mgcapsules, 100mg; 250mgsyrup, 50mg/5ml6.5.2.2 Non-Nucleoside Reverse Transcriptase Inhibitors1. Efavirenz 3 capsules, 50mg, 100mg,200mg, 600mgsyrup, 30mg/mlEritrean National List of Medicines 2010 Page 41

LevelDrugof Dosage form and StrengthUse2. Nevirapine 3 tablet, 200mg3. Stavudine +Lamivudine +Nevirapineoral suspension, 10mg/ml3 tablet,Stavudine 30mg +Lamivudine 150mg +Nevirapine 200mg;4. Tenofovir 5. 3 tablet,300mg6.5.2.3 Protease Inhibitors1. Lopinavir + ritonavir 3 capsule, lopinavir 133.3mg +ritonavir 33.3mgoral solution lopinavir ,80mg/ml + ritonavir20mg/ml2. Ritonavir 3 capsule, 100mg, 200mgOral liquid: 400 mg/5 ml.Tablet (heat stable): 25 mg;100 mg.3. Saquinavir 3 capsule, 200mg6.6 Insect Repellents1. Diethyltoluamide 1 topical solution, 50%, 75%7. ANTIMIGRAINE MEDICINES7.1 For Treatment of Acute Attack1. Acetylsalicylic acid 1 tablet, 300mg, 500mg2. Ergotamine tartrate 2 tablet, 2mg3. Ergotamine tartrate + 2 tablet, 2mg + 100mgcaffeine4. Paracetamol 1 tablet, 300mg - 500mgEritrean National List of Medicines 2010 Page 42

DrugLevelofUseDosage form and Strength8. ANTINEOPLASTIC AND IMMUNOSUPPRESSIVEMEDICINES8.1 Immunosuppressive Medicines1. Azathioprine sodium SS8.2 Cytotoxic Medicinestablet, 50mgpowder for injection 100mgin vial1.L-asparaginase S powder for injection,10000IU in vial2.Bleomycin sulfate S powder for injection, 15mg invial3.Busulfan S tablet, 2mg4.Carmustine S powder for injection, 100mgin vial5.Chlorambucil S tablet, 2mg6.Cytarabine S powder for injection,100mgin vial7.DoxorubicinS powder for injection, 10mg,hydrochloride8.Folinic acid50mg in vialscored tablet, 15mginjection, 3mg/mlSS9.Thioguanil S tablet, 40mg10.Fluorouracil S injection, 50mg/ml in 5mlampoule11.Hydroxyurea S capsule, 500mg12.Mercaptopurine S tablet, 50mgEritrean National List of Medicines 2010 Page 43

Drug13.Methotrexate sodiumLevelofUseSSDosage form and Strengthtablet 2.5mgPowder for injection, 50mg invialcapsule, 50mg14.Procarbazine hydrochlorideS15.Vinblastine sulphate S powder for injection, 10mg invial16.Vincristine sulfate S powder for injection, 1mg,5mg in vial8.3 Hormones and Antihormones1. Dexamethasone SStablet, 500g, 4mginjection 4mg in 1ml ampoule(as sodium phosphate)oral liquid: 2 mg/5 ml.2. Ethinylestradiol S tablet, 50g3. Hydrocortisone SSscored tablet, 10mginjection, 100mg/ml4. Prednisolone SStablet, 5mginjection, 20mg, 25mg in vial(as sodium succinate)oral liquid: 5 mg/ml.5. Tamoxifen citrate S tablet, 10mg, 20mg9. ANTIPARKINSONISM MEDICINES1.Biperiden hydrochloride 3 injection, 5mg in 1mlampoule (as lactate)2.Levodopa + Carbidopa 3 tablet, 100mg + 10mg, 250 +25mg3. Benzhexol 3 tablet, 2mg, 5mgEritrean National List of Medicines 2010 Page 44

DrugLevelofUseDosage form and Strength10. MEDICINES AFFECTING THE BLOOD10.1 Antianaemia Medicines1. Ferrous salt 11tablet, equivalent to 60mgironoral solution or syrup,equivalent to 25mg iron/ml(as sulfate)2. Ferrous salt + Folic 1 tablet, 60mg + 400mgacid3. Folic acid 13tablet, 1mg, 5mginjection, 1mg in 1mlampoule (as sodium salt)4. Hydroxocobalamine 3 injection, 1mg in 1mlampoule5. Iron dextran 3 injection, equivalent to 50mgiron/ml in 2ml ampoule10.2 Anticoagulants and Antagonists1. Heparin 3 injection, 1000 IU/ml, 5000IU/ml, 20000 IU/ml in lmlampoule2. Phytomenadione 2 injection, 10mg/ml in 5mlampoule3. Protamine sulfate 3 injection, 10mg/ml in 5mlampoule4. Warfarin sodium S tablet, 1mg, 2mg, 5mgEritrean National List of Medicines 2010 Page 45

DrugLevelofUseDosage form and Strength11. BLOOD PRODUCTS AND PLASMASUBSTITUTES11.1 Plasma Substitutes1. Dextran 3 injectable solution, 6%2. Polygeline 3 injectable solution, 3.5-4%11.2 Plasma Fractions for Specific Uses1. Albumin, human 3 injectable solution, 5%, 25%2.FactorVIII concentrate S dried3. Factor IX complexconcentrateS dried (coagulation factor II,IX, X)4. Human plasma protein 3 injectable solution, 4-5%fractionisotonic solution12. CARDIOVASCULAR MEDICINES12.1 Antianginal Medicines1. Glyceryl trinitrate 3 tablet, (sublingual), 500mg2. Isosorbide dinitrate 3 tablet, (sublingual), 5mg,10mg3. Nifedipine 3 capsule or tablet, 5-20mg4.Propranololhydrochloride33tablet, 10mg, 40mginjection, 1mg in 1mlampoule5. Atenolol 3 tablet, 25mg, 50mgEritrean National List of Medicines 2010 Page 46

DrugLevelofUseDosage form and Strength12.2 Antidysrhythmic Medicines1.Propranololhydrochloride33tablet, 10mg, 40mginjection, 1mg in 1mlampoule2. Quinidine sulfate S tablet, 200mg3. Verapamil3hydrochloride3tablet, 40mg, 80mginjection, 2.5mg/ml in 2mlampoule4. Procainamide S injection, 100mg/ml in 10mlvial5. Lidocaine S injection, 1%, 2% in vial12.3 Antihypertensive Medicines1. Captopril 3 scored tablet, 25mg2. Hydralazine3hydrochloride3tablet, 25mg, 50mgpowder for injection, 20mg inampoule3. Hydrochlorothiazide 2 tablet, 25mg4. Methyldopa 3 tablet, 250mg5. Nifedipine 3 capsule or tablet, 5-20mg6. Amlodipine 3 Tablet, 5mg, 10mg7. Propranolol3 tablet, 20mg, 40mghydrochloride8. Enalapril 3 tablet 2.5mg, 5mg, 10mg9. Labetalol 3 injection, 5mg/ml ampoule10. Reserpine 33tablet, 100mg, 250mginjection,1mg in 1ml ampouleEritrean National List of Medicines 2010 Page 47

DrugLevelofUseDosage form and Strength12.4 Cardiac Glycosides1. Digoxin 23312.5 Medicines Used In Vascular Shocktablet, 62.5mg, 250mgoral solution, 50mg/mlinjection, 250mg/ml in 2mlampoule1. DopaminehydrochlorideS injection, 40mg/ml,160mg/ml in 5ml ampoules2. Dobutamine S injection, 50mg/ml in 5mlvial12.6 Antithrombotic Medicines1. Acetylsalicylic acid 3 tablet, 100mg12.7 Lipid-lowering medicines1. Atorvastatin S tablet, 10mg, 20mg, 40mg2. Simvastatin 3 tablet, 10mg,40mg13. DERMATOLOGICAL MEDICINES13.1 Antifungal Medicines (Topical)1. Benzoic acid + salicylic 1 ointment/cream, 6% + 3%acid2. Clotrimazole 1 ointment/cream, 1%3. Nystatin 2 ointment/cream, 100,000 IU/g4. Selenium sulfide 1 shampoo, 2%5. Miconazole 1 ointment/cream, 2%6. Ketoconazole cream 2 cream 2%7. Aciclovir 3 cream 5%Eritrean National List of Medicines 2010 Page 48

DrugLevelofUseDosage form and Strength13.2 Anti-Infective Medicines1. Methylrosaniliniumchloride (gentianviolet)2. Neomycin sulfate +Bacitracin zinc11aqueous solution, 0.5%tincture, 0.5%1 ointment, 5mg neomycinsulfate + 500 IU bacitracinzinc/g3. Silver sulfadiazine 2 cream, 1% in 500g container13.3 Anti-Inflammatory and Antipruritic Medicines1. Betamethasone valerate 3 ointment/cream, 0.1%2. Calamine lotion 1 lotion3. Hydrocortisone acetate 2 ointment/cream, 1%13.4 Astringent Medicines1. Aluminium diacetate 3 solution, 13% for dilution13.5 Keratoplastic and Keratolytic Agents1. Benzoyl peroxide 3 lotion or cream, 5%gel, 3%, 5%, 10%2. Coal tar 2 solution, topical 5%3. Dithranol 2 ointment, 0.1 – 2%4. Fluorouracil S ointment, 5%5. Ichthammol 1 ointment, 10%6. Isotretinoin S gel, 0.05%7. Podophyllum resin 3 solution, topical 10 – 25%8. Salicylic acid 1 solution, topical 5%13.6 Scabicides and Pediculicides1. Benzyl benzoate 1 lotion, 25%Eritrean National List of Medicines 2010 Page 49

LevelDrugofUseDosage form and Strength2. Permethrin 2 lotion, 1%Cream: 5%.14. DIAGNOSTIC AGENTS14.1 Ophthalmic Medicines1. Fluorescein sodium 3 strip2. Tropicamide S eye drops, 0.5%3. Rose Bengal S eye drops, 1%4. Schirmers’ test S paper14.2 Radiocontrast Media1. Amidotrizoate sodiumor meglumine salt2. Barium sulfate 3 aqueous suspension3. Gadopentate3dimeglumine34. Propyliodone 33 injection, 140-420mgiodine/ml in 20ml ampoule3oral solution 9.38mg/mlinjection, 469.01mg/ml in 5-20ml vialsaqueous suspension, 500 –600mg/ml in 20mlampouleoily suspension, 500 –600mg/ml in 20mlampoule5. Diotroxate meglumine 3 injectable solution, 5-8giodine in 100-250ml6. Iohexol 3 injectable solution, 140–350mg iodine per ml7. Iopamidol 3 injectable solution, 128–370mg iodine per ml8. Iopromide 3 injectable solution, 150–370mg iodine per mlEritrean National List of Medicines 2010 Page 50

LevelDrugof Dosage form and StrengthUse9. Iotrolan 3 injectable solution, 240–300mg iodine per ml15. DISINFECTANTS AND ANTISEPTICS1. Calcuim hypochlorite 1 powder for solution (70%available chlorine)2. Chlorhexidine1 solution, 5% for dilutiondigluconate3. Formaldehyde 2 solution, 40%4. Glutaraldehyde 3 solution, 2%5. Hydrogen peroxide 1 solution, 3%6. Iodine 1 solution, 2.5%7. Potassium1 tablet, 300mgpermanganate8. Alcohol Denatured 1 solution9. Chlorhexidine+Cetrimide1 solution, 0.015% + 0.15%16. DIURETICS1. Furosemide 33tablet, 10mg, 20mg, 40mginjection, 10mg/ml in 2mlampouleoral liquid: 20mg/5ml2.Hydrochlorothiazide 2 tablet, 25mg, 50mg3. Mannitol 3 injectable solution,10%, 20%4. Spironolactone 3 tablet, 25mgoral liquid: 5mg/5ml,10mg/5ml and 25mg/5mlEritrean National List of Medicines 2010 Page 51

DrugLevelofUseDosage form and Strength17. EAR NOSE AND THROAT PREPARATIONS17.1 Ear Preparations1. Chloramphenicol 2 ear drops, 5%, 10%2. Polymixin + Neomycin 3 ear drops, 10000 IU + 0.5%3. Polymixin +Neomycin +S ear drops, 10000 IU + 0.5% +1%Hydrocortisone4. Salicylic acid 2 ear drops 2%5. Boric acid 2 ear drops 2.75%6. Hydrocortisone +PolymixinB +Oxytetracycline7. Nystatin 1 ear drops17.2 Nose Preparations1. XylometazolineHydrochloride2. BeclomethasonedipropionateS eye/ear drop, 15mg + 10000-units +5mg2 nasal drops, 0.05%, 0.1%18. GASTROINTESTINAL MEDICINES3 nasal spray, 50micrometer permetered spray18.1 Antacid and Other Antiulcer Medicines1. Aluminium hydroxide 112. Aluminium hydroxide 2+ Magnesium2hydroxidetablet, 500mgoral suspension, 320mg/5mltablet, 220mg + 195mgoral suspension, 220mg +195mg/5mlEritrean National List of Medicines 2010 Page 52

LevelDrugofUse3. Cimetidine 3Dosage form and Strengthinjection, 100mg/ml in 2mlampouletablet, 200mg, 400mg34. Famotidine 2 tablet, 20mg, 40mg,5. Magnesiumhydroxide2 oral suspension, equivalent to550mg magnesiumoxide/10ml6. Omeprazole 3 Tablet/capsule, 20mgPowder for oral liquid: 20mg, 40 mg sachets.7. Ranitidinehydrochloride18.2 Antiemetic Medicines1. Hyoscine hydrobromide 222. Meclozine HCl +Pyridoxine HCl3.Metoclopramidehydrochloride4.Promethazinehydrochloride1 tablet, 150 - 300mgoral liquid, 75 mg/5 ml11tablet, 300mginjection, 400mg/ml in 1mlampoule2 tablet, 25mg + 50mg222tablet, 10mginjection, 5mg/ml in 2mlampoulesyrup, 5mg/5mltablet, 10mg, 25mgelixir or syrup, 5mg/5mlinjection, 25mg/ml in 2mlampouleEritrean National List of Medicines 2010 Page 53

DrugLevelofUseDosage form and Strength18.3 Antihaemorrhoidal Medicines1. Antihaemorrhoidalpreparation18.4 Anti-Inflammatory Medicines2 ointment or suppository(containing anaesthetic,astringent and antiinflammatorymedicine)1. Hydrocortisone acetate 3 suppository, 25mg2. Sulfasalazine 3 tablet, 500mg18.5 Antispasmodic Medicines1.Dicyclomine HCl 1222. Hyoscinebutylbromide18.6 Cathartic Medicines121. Bisacodyl 11tablet, 10mginjection, 20mg/mlsyrup 10mg/5mltablet, 10mginjection, 20mg/ml inampouletablet, 5mgsuppositories,10mg,(paediatric, 5mg)1ml2. Glycerol 1 suppositories, 140mg, 700mg3. Lactulose 3 Solution,3.1-3.7mg/5ml4. Magnesium sulfate 3 sachet5. Senna 1 tablet, 7.5mg6. Sodium phosphaterectal3 suppositories, 1.72gEritrean National List of Medicines 2010 Page 54

DrugLevelofUseDosage form and Strength18.7 Medicines Used In Diarrhoea1. Oral Rehydration Salts 1 powder, 20.5 g/lSodium chloride 2.6 g/lTrisodium citrate 2.9 g/lPotassium chloride 1.5 g/lGlucose 13.5 g/lzinc sulfate 11tablet, 10mg, 20mg per unitdosage formsyrup 10mg per unit dosageform18.7.1 Antidiarrhoeal (Symptomatic) Medicines1. Codeine phosphate 3 tablet, 30mg2. Loperamide 2 capsule or tablet, 2mg19. HORMONES, OTHER ENDOCRINE MEDICINESAND CONTRACEPTIVES19.1 Adrenal Hormones and Synthetic Substitutes1. Dexamethasone sodiumphosphate33tablet, 500mg, 4mginjection, 4mg in 1mlampoule2. Fludrocortisone S tablet, 100mg3. Hydrocortisone sodiumsuccinate3 powder for injection, 100mgin vial4. Methyl prednisolone 3 injection, 40mg/ml in vialacetate5. Prednisolone 3 tablet, 1mg, 5mgEritrean National List of Medicines 2010 Page 55

DrugLevelofUseDosage form and Strength19.2 Androgens1. Testosterone enantate 3 injection, 200mg in 1mlampoule2. Mesterolone S tablet, 25mg3. Danazol 3 capsule, 200mg19.3 Contraceptives19.3.1 Hormonal Contraceptives1. Ethinylestradiol +Levonorgestrel1 tablet, 30mg + 150mg, 30mg +250mg2. Ethinylestradiol + 1 tablet, 35mg + 1mgNorethisterone3. Depot medroxyprogesterone-acetate2 injection, 150mg/ml in 1mlvial, 50mg/ml in 3ml vial4.Norethisterone 3 tablet, 350mg5. Norethisteroneenantate3 oily solution, 200mg/ml in1ml ampoule6. Levonorgestrelreleasing implant3 implant capsule,38mg/implant capsule7. Norgestrel 3 tablet, 75mg8. Lynoestrenol 3 tablet, 500mg19.3.2 Intrauterine Device1. Copper containingdevice2Eritrean National List of Medicines 2010 Page 56

DrugLevelofUseDosage form and Strength19.3.3 Barrier Methods1. Condoms with or 1without spermicide(nonoxinol)2.Diaphragm with2spermicide (nonoxinol)3.Female condoms 119.4 Estrogens1. Ethinylestradiol 3 tablet, 10mg, 50mg2. Conujugated estrogens S tablet, 0.3mg, 0.625mg,0.9mg, 1.25mg, 2.5mg3. Estradiol valerate S tablet, 2mg19.5 Insulins and Other Antidiabetic Agents1. Insulin(soluble/normal)2.Intermediate actinginsulin (as compoundinsulin zinc suspensionor isophaneinsulin/lente)3. Biphasic Isophaneinsulin2 injection, 100 IU/ml in 10mlvial2 injection, 100 IU/ml in 10mlvial2 injection, 30% soluble+70%isophane 100 IU/ml in 10mlvial4. Glibenclamide 2 scored tablet, 5mg5. Metformin3 tablet, 500mgHydrochloride6. Glimipride 3 Tablet, 1, 2, 3, 4mgEritrean National List of Medicines 2010 Page 57

DrugLevelofUseDosage form and Strength19.6 Ovulation Inducers1. Clomifene citrate 3 tablet, 50mg2. Bromocriptine S tablet, 2.5mg3. Human Chorionic S injection, 1000-5000Gonadotropinunit/amp19.7 Progestogens1. Norethisterone 3 tablet, 5mg2.Medroxyprogesteronehexanoate33tablet, 5mgoily injection, 250mg/mlampoule19.8 Thyroid Hormones and Antithyroid Medicines1.Levothyroxine sodium S tablet, 50mg, 100mg2. Aqueous iodinesolution (Lugol's3 oral solution, total iodine130mg/mlsolution)3. Propylthiouracil 3 tablet, 50mg19.9 Medicines for Erectile Dysfunction1. Testosterone enantate 3 injection, 200mg in 1mlampoule2. Sildenafil 3 tablet, 25mg, 50mg20. IMMUNOLOGICALS20.1 Diagnostic Agents1. Tuberculin, purifiedprotein derivative PPDSinjectionEritrean National List of Medicines 2010 Page 58

DrugLevelofUseDosage form and Strength20.2 Sera and Immunoglobulins1. Anti-Dimmunoglobulin(Human)3 injection, 250mg-300mg insingle dose vial2. Antiscorpion sera 1 injection3. Antitetanusimmunoglobulin(Human)3 injection, 500IU in vial4. Antivenom sera 1 injection5. Diphtheria antitoxin 3 injection, 10,000IU,20,000IU in vial6. Immunoglobulin,human normal7. Rabiesimmunoglobulin8. Tetanus antitoxin(equine)20.3 Vaccines3 injection20.3.1 For Universal Immunization3 injection, 150IU/ml in vial1 injection, 5,000IU in vial1. BCG vaccine (dried) 1 injection2. Diphtheria-pertussistetanus1 injectionvaccine3. Diphthera- tetanus 1 injectionvaccine4. Measles-Mumpsrubella1 injectionvaccine5. Measles vaccine 1 injectionEritrean National List of Medicines 2010 Page 59

LevelDrugofUseDosage form and Strength6. Poliomyelitis vaccine 1 injection(inactivated)7. Poliomyelitis vaccine 1 oral solution(live attenuated)8. Tetanus vaccine 1 injection20.3.2 For Specific Groups of Individuals1. Hepatitis B Vaccine S injection2. Meningococcal vaccine 3 injection3. Rabies vaccine 3 injection4. Rubella vaccine 3 injection5. Typhoid vaccine 3 injection6. Yellow fever vaccine S injection21. MUSCLE RELAXANTS (PERIPHERAL) ANDCHOLINESTERASE INHIBITORS1. Atracurium S injection, 10mg/ml in 2.5ml,5ml ampoule2. Neostigmine-bromide 33tablet, 15mginjection, 500mg, 2.5mg in1ml ampoule (asmetilsulfate)3. Pancuronium bromide 3 injection, 2mg/ml in 2mlampoule3 injection, 50mg/ml in 2mlampoule4. Suxamethoniumchloride5. Vecuronium bromide 3 powder for injection, 10mgin vialEritrean National List of Medicines 2010 Page 60

DrugLevelofUseDosage form and Strength22. OPHTHALMOLOGICAL PREPARATIONS22.1 Anti-Infective Agents1. Gentamicin 3 solution (eye drops), 0.3%2. Trifluridine S solution (eye drops), 1%,3. Aciclovir 3 solution (eye drops), 3%4. Tetracycline1 eye ointment, 1%hydrochloride5. Chloramphenicol 22solution (eye drops), 0.5%eye ointment, 1%6. Natamycin S solution (eye drops), 5%7. Ofloxacin 3 solution (eye drops), 0.3%8. Dorzolamide + timolol S drop, 2% + 0.5%9. Ciprofloxacin S drop, 0.3%10. Latonoprost S drop, 0.005%11. Azithromycin S capsule 250mgsyrup, 200mg/5ml22.2 Anti-Inflammatory Agents1. Prednisolone 3 solution (eye drops), 0.5% assodium phosphate, 1% asacetate2. Dexamethasone 3 solution (eye drops), 0.05-0.1%3. Hydrocortisone acetate 3 eye ointment, 1%4. Hydrocortisone +Polymixin B +Oxytetracycline5.MethylprednisoloneacetateS eye/ear drop, 15mg + 10000-units +5mgSinjection, 40mg/ml vialEritrean National List of Medicines 2010 Page 61

LevelDrugofUseDosage form and Strength6. Lodoxamide 3 eye drop, 0.1%7. Diclofenac sodium 3 eye drop, 0.1%22.3 Local Anaesthetics1.Tetracainehydrochloride3 solution (eye drop), 0.5%22.4 Miotics and Antiglaucoma Medicines1. Acetazolamide 33tablet, 250mgpowder for injection2. BetaxololS solution (eye drops) 0.5%Hydrochloride3. Dorzolamide S solution (eye drops) 2%4. Pilocarpine3 solution (eye drops), 2%, 4%hydrochloride ornitrate5. Timolol maleate S solution (eye drops) 0.25%,0.5%22.5 Mydriatics1. Atropine sulfate 3 solution (eye drops), 0.1%,0.5%, 1%2. HomatropineS solution (eye drops), 2%hydrobromide3. Phenylephrine 3 solution (eye drops),2.5%,10%22.6 Miscellaneous Ophthalmic Preparations1. Naphazoline HCl 3 solution (eye drops), 0.05%Eritrean National List of Medicines 2010 Page 62

Drug2. NaphazolineHydrochloride +Antazoline phosphate3. Hydroxymethylcellulose4. Acetylcholine Cl +Levelof Dosage form and StrengthUse3 solution (eye drops), 0.05%+ 0.5%S injection, 0.3% - 2%Spowder for injectionMannitol 3%5. Methyl cellulose S eye drop, 0.5 - 1%6. Diclofenac sodium S eye drop, 0.1%23. OXYTOCICS and ANTIOXYTOCICS23.1 Oxytocics1. Ergometrine hydrogen 1 tablet, 200mg, 500mgmaleate1 injection, 200mg in 1mlampoule2. Oxytocin 1 injection, 5IU/ml, 10IU/ml3. Prostaglandin E 1(Misoprostol)23.2 Antioxytocics1. Salbutamol sulfate 2Sampoule3 Tablet, 25mcg, 200mcg24. PERITONEAL DIALYSIS SOLUTIONtablet, 2mg, 4mginjection, 50mg in 5mlampoule1. Intraperitoneal dialysisparenteral solutionS appropriate composition (ofnecessary ingredients)2. Glycine S irrigation solution, 1.5% inwater for injectionEritrean National List of Medicines 2010 Page 63

DrugLevelofUseDosage form and Strength25. PSYCHOTHERAPEUTIC MEDICINES1. Amitriptyline3 tablet, 25mg, 50mg, 75mghydrochloride2. Caffeine Citrate S3. Chlorpromazinehydrochloride333tablet, 25mg, 100mgsyrup, 25mg/5mlinjection, 25mg/ml in 2mlampoule4. Diazepam 2 scored tablet, 2mg, 5mg5. Fluoxetine 336. Fluphenazinedecanoate orenantate7. Haloperidol 338. Lithium carbonate 33capsule, 20mg, 60mgliquid(as hydrochloride),20mg/5ml3 injection, 25mg in 1mlampoule3tablet, 2mg, 5mgoral liquid, 2mg/5ml,10mg/5mlinjection, 5mg/ml in 2mlampoulecapsule or tablet, 300mginjection, 5mg in 1mlampoule9. Thioridazine 3 tablet, 25mg, 100mgEritrean National List of Medicines 2010 Page 64

DrugLevelofUseDosage form and Strength26. MEDICINES ACTING ON THE RESPIRATORYTRACT26.1 Antiasthmatic Medicines1. Aminophylline 11tablet, 100mg, 200mginjection, 25mg/ml in 10mlampoule2.Beclomethasonedipropionate3 inhalation (aerosol), 50mgper dose3.Cromoglicic acid 3 inhalation, (aerosol), per dose(sodium)4.Epinephrine2 injection, 1mg in 1mlhydrochlorideampoule5.Salbutamol sulfate 12233tablet, 2mg, 4mgsyrup, 2mg/5mlinhalation (aerosol), 100mgper doseNebuliser solution, 5mg/ml assulfateinjection, 50mg/ml in 5mlampoule6.Ephedrinehydrochloride123tablet, 30mgelixir, 15mg/5mlinjection, 50mg in 1mlampoule (as sulfate)Eritrean National List of Medicines 2010 Page 65

DrugLevelofUseDosage form and Strength26.2 Antitussives1. chlorphenamine 2Maleate,pseudoephedrinehydrochloride andParacetamol2. Citric acid1 pediatric syrup, 0.625%monohydrate (Simplelinctus)3. Codeine phosphate 1 linctus, 15mg/5ml4. Dextromethorphan 11tablet, 15mgsyrup, 15mg/5ml26.3 Respiratory stimulant and pulmonary surfactants1 Beractant S Suspension, 25mg/ml26.4 Mucolytic medicines1. Bromohexine 2 Syrup 4mg/5ml (asHydrochloride)27. SOLUTIONS CORRECTING WATER,ELECTROLYTE AND ACID BASEDISTURBANCES27.1 Oral Rehydration1. Oral rehydration salts(for glucose electrolytesolution)1 powder, 20.5 g/lSodium chloride 2.6 g/lTrisodium citrate 2.9 g/lPotassium chloride 1.5 g/lGlucose 13.5 g/lEritrean National List of Medicines 2010 Page 66

LevelDrugofUse2. Potassium chloride 2233. Zinc sulphate 1127.2 ParenteralDosage form and Strengthpowder for solutiontablet, 250mg, 600mginjectable solution, 11.2%ampouletablet, 20mg, 125mgsyrup1. Ringer Lactate 1 injectable solution2. Glucose 1 injectable solution, 5%isotonic, 50% hypertonic3.Glucose with sodiumchloride1 injectable solution, 4%glucose + 0.18% sodiumchloride (30mmol/l sodiumsolution)4.Potassium chloride 3 injectable solution, 1.5mmol/in 20ml ampoule5.Sodium bicarbonate 3 injectable solution, 1.4%isotonic (167mmol/l solution)8.4% solution in 10mlampoule (1mol/l solution)6. Sodium chloride 127.3 Miscellaneous2injectable solution, 0.9%isotonic (154 mmol/lsolution)injectable solution, 2.5%, 3%hypertonic in ampoules1.Water for injection 1 2ml, 5ml, 10ml ampouleEritrean National List of Medicines 2010 Page 67

DrugLevelofUseDosage form and Strength28. VITAMINS AND MINERALS1. Ascorbic acid 13tablet, 50mg, 250mginjection 100mg/ml ampoule2.Calcium gluconate 23tablet, 300g, 600ginjection 10% in ampoule3. Ergocalciferol 223capsule or tablet,1.25mg(50,000IU)oral solution, 250mcg/ml(10,000IU/ml)injection 7.5mg(300000units)in ampoule4. Pyridoxinehydrochloride22tablet, 25mg, 50mginjection, 100mg/ml5. Retinol (as palmitate) 1123sugar coated tablet, 10,000IU(5.5mg)capsule, 200,000IU (110mg)oral oily solution, 100,000IUper ml in multidose dispenserwater miscible injection100,000IU (55mg) in 2mlampoule6. Thiaminehydrochloride23tablet, 50mginjection, 100mg/ml7. Vitamin B complex 1 tablet1 syrup3 injection8.Vitamin B1, B6 and 3 injectionB129. Multivitamin 11tabletsyrupEritrean National List of Medicines 2010 Page 68

LevelDrugofUseDosage form and Strength10. ORS + Minerals 1 oral solution11. Iodine 1 Capsule: 200 mg.12. Riboflavin 1 Tablet: 5 mg.Iodized oil: 0.5 ml (240 mgiodine) in ampoule (oral orinjectable); 0.57 ml (308 mgiodine) in dispenser bottle; 1ml (480 mg iodine).13. Sodium fluoride 1 In any appropriate topicalformulation.Eritrean National List of Medicines 2010 Page 69

Eritrean National List of Medicines 2010 Page 71

INDEX· Bold face type indicates a medicine as is shown in the medicinelist.· Equal sign indicates that both names are generic· Brand names which are commonly used in Eritrea are included inthe index to assist prescribers in the national change-over togeneric names3TC. =lamivudineAbacavir, 41ABC. =abacavirAcetazolamide eye, 62Acetylcholine Cl + Mannitol3% eye, 63Acetylsalicylic acid, 29, 42,48Aciclovir, 40, 48Aciclovir eye, 61Albendazole, 33Albumin, 46Alcohol, 51Allopurinol, 29Alomide. See lodoxamideAluminium diacetate, 49Aluminium hydroxide, 52Aluminium hydroxide +Magnesium hydroxide,52Amidotrizoate, 50Amikacin, 35Amikin. See amikacinAminophylline, 65Amitriptyline, 64Amlodipine, 47Ammoxicilin + Clavulanicacid, 34Amodiaquine, 39Amoxicillin, 33Amphotericin, 38Ampicillin, 34Amukin. See amikacinAngiotec. See enalaprilAnti-D immunoglobulin, 59Antihaemorrhoidal Drug, 54Antiscorpion sera, 59Antitetanusimmunoglobulin, 59Antivenom sera, 59Artane. See benzhexolEritrean National List of Medicines 2010 Page 73

Artemether +lumefantrine, 40Artesunate, 39Ascorbic acid, 68Asparaginase, 43Atenolol, 46Atorvastatin, 48Atracurium, 60Atropine, 28, 31Atropine eye, 62Avamigran. See ergotamine+ caffeineAzathioprine, 43Azemol. See paracetamolAzithromycin, 61AZT. =zidovudineBarium sulfate, 50BCG vaccine, 59Beclomethasone, 52, 65Bentex. See benzhexolBenzathine benzyl penicillin,34Benzhexol, 44Benzoic acid + salicylic acid,48Benzoyl peroxide, 49Benzyl benzoate, 49Benzyl penicillin, 34Beractant, 66Betamethasone, 49Betaxolol eye, 62BiCNU. See carmustineBiperiden, 44Biphasic isophane insulin,57Bisacodyl, 54Bleomycin, 43Boric acid, 52Bromocriptine, 58Bromohexine, 66Bupivacaine, 27Busulfan, 43Cafergot. See ergotamine +caffeineCaffeine Citrate, 64Calamine lotion, 49Calcium gluconate, 68Calcuim hypochlorite, 51Captopril, 47Carbamazepine, 32Carmustine, 43Ceftazidime, 35Ceftriaxone, 35Cetrizine, 30Charcoal, 30Chlorambucil, 43Chloramphenicol, 35, 52Chloramphenicol eye, 61Chlorhexidine, 51Chlorhexidine + Cetrimide,51Chloroquine, 39, 40Chlorphenamine, 30Eritrean National List of Medicines 2010 Page 74

chlorphenamine Maleate,pseudoephedrinehydrochloride andParacetamol, 66Chlorpromazine, 64Chorionic Gonadotropin,Human, 58Cimetidine, 53Ciprofloxacin, 35, 61Citric acid monohydrate, 66Clarithromycin, 35Clindamycin, 35Clofazimine, 36Clomifene, 58Clonazepam, 32Clotrimazole, 38, 48Cloxacillin, 34Coal tar, 49Codeine, 29, 66Codeine phosphate, 55Colchicine, 29Combivir. See zidovudine +lamivudineCondoms, 57Conujugated estrogens, 57Co-trimoxazole. =Sulfadoxine +pyrimethaneCromoglicic acid, 65Cycloserine, 38Cytarabine, 43d4T. =stavudinedacarbazine, 20Dakatrin. See miconazoleDanazol, 56Daonil. See glibenclamideDapsone, 36ddI. =didanosineDeferoxamine, 31Depo-Provera. See Depotmedroxy-progesteroneacetateDepotmedroxyprogesterone, 56Dexamethasone, 20, 30, 44,55Dexamethasone eye, 61Dextran, 46Dextromethorphan, 66Diaphragm, 57Diazepam, 28, 32, 64Diclofenac, 29Diclofenac eye, 62, 63Dicyclomine, 54Didanosine, 41Diethylcarbamazine, 33Diethyltoluamide, 42Digoxin, 48Diloxanide, 38Dimercaprol, 31Dinex. See didanosineDiotroxate, 50Diphthera-tetanus vaccine,59Diphtheria antitoxin, 59Eritrean National List of Medicines 2010 Page 75

Diphtheria-pertussis-tetanusvaccine, 59Dithranol, 49Dobutamine, 48Dobutrex. See dobutamineDopamine, 48Dorzolamide, 62Dorzolamide + timolol, 61Doxorbicin, 43Doxycycline, 35, 39Duovir. See Zidovudine +LamivudineDynatra. See dopamineEfavirenz, 41EFV. =efavirenzElspar. See asparagenaseEnalapril, 47Ephedrine, 65Epinephrine, 30, 65Epivir. See lamivudineEpsom salt. = magnesiumsulfateEquine. = tetanus antitoxineErgocalciferol, 68Ergometrine, 63Ergotamine, 42Ergotamine + caffeine, 42Erythromycin, 36Estradiol valerate, 57Estrogens, conujugated, 57Ethambutol, 37Ether, 27Ethinylestradiol, 44, 57Ethinylestradiol +Levonorgestrel, 56Ethinylestradiol +Norethisterone, 56Ethinyltestosterone. =danazolEthionamide, 38Ethisterone. =danazolEthosuximide, 32Ethyl Chloride, 28Eugynon. SeeEthinylestradiol +LevonorgestrelExluton. See lynoestrenolFactor IX, 46FactorVIII, 46Famotidine, 53Fancidar. See Sulfadoxine +pyrimethamineFemale condoms, 57Femodette. SeeEthinylestradiol +NorethisteroneFerrous salt, 45Ferrous salt + Folic acid, 45Floxapen. See flucloxacillinFlucloxacillin, 34Fluconazole, 38Fludrocortisone, 55Fluorescein, 50Fluorouracil, 43, 49Fluoxetine, 64Eritrean National List of Medicines 2010 Page 76

Fluphenazine, 64Folic acid, 45Folinic acid, 43Formaldehyde, 51Funzole. See FluconazoleFurosemide, 51Gadopentate dimeglumine,50Gentamicin, 36Gentamicin eye, 61Glibenclamide, 57Glimipride, 57Glucose, 67Glucose + sodium chloride,67Glutaraldehyde, 51Glycerol, 54Glyceryl trinitrate, 46Glycine, 63Griseofulvin, 38Haloperidol, 64Halothane, 27Hartmann's solution. = ringerlactateHeparin, 45Hepatitis B vaccine, 60Homatropine eye, 62Hydralazine, 47Hydrochlorothiazide, 47, 51Hydrocortisone, 30, 44, 49,54, 55Hydrocortisone + Polymixin+ Oxytetracycline, 52Hydrocortisone + Polymixin+ Oxytetracycline eye, 61Hydrocortisone eye, 61Hydrogen peroxide, 51Hydroxocobalamine, 45Hydroxypropylmethylcellulose eye, 63Hydroxyurea, 43Hyoscine butylbromide, 54Hyoscine hydrobromide, 53Ibuprofen, 29Ichthammol, 49Immunoglobulin, 59Indomethacin, 29Innovace. See enalaprilInsulin, 57Intermediate acting insulin,57Intraperitoneal dialysisparenteral solution, 63Intrauterine device, 56Invirase. See saquinaviriodine, 69Iodine, 51, 69Iodine solution, 58Iohexol, 50Iopamidol, 50Iopromide, 50Iotrolan, 51Ipecacuanha, 31Eritrean National List of Medicines 2010 Page 77

Iron dextran, 45Isoniazid, 37Isoniazide + ethambutol, 37Isoniazide + rifampicin+pyrazinamide +ethambutol, 37Isosorbide dinitrate, 46Isotretinoin, 49Ivermectin, 33Kaletra. See lopinavir +ritonavirKanamycin, 38Ketamine, 27Ketoconazole, 38, 48KY Jelly, 28Labetalol, 47Lactulose, 54Lamivir. See lamivudineLamivudine, 41L-asparaginase, 43Latonoprost, 61Levodopa + Carbidopa, 44Levonorgestrel, 56Levothyroxine, 58Lidocaine, 19, 28, 47Lithium carbonate, 64Lodoxamide eye, 62Loestrin. SeeEthinylestradiol +NorethisteroneLoperamide, 55Lopinavir + Ritonavir, 42Losec. See omiprazoleLPV/r. =lopinavir +ritonavirLugol's solution. See iodinesolutionLynoestrenol, 56Macrodantin. SeenitrofurantoinMagaldrate. = aluminiumhydroxide + magnesiumhydroxideMagnesium hydroxide, 53Magnesium sulfate, 32, 54Maloxan. SeemetoclopramideMannitol, 51Measles vaccine, 59Measles-Mumps-rubellavaccine, 59Mebendazole, 33Meclozine + Pyridoxine, 53Medroxyprogesterone, 56,58Mefloquine, 39Meglumine antimonate, 39Meningococcal vaccine, 60Mepral. See omiprazoleMercaptopurine, 43Mercilon. SeeEthinylestradiol +NorethisteroneMesterolone, 56Metformin, 57Methionine, 31Eritrean National List of Medicines 2010 Page 78

Methotrexate, 44Methyl celclulose eye, 63Methyldopa, 47Methylprednisolone, 55Methylprednisolone eye, 61Methylrosanilinium, 49Methylthioninium, 31Metoclopramide, 28, 53Metronidazole, 36, 38Miconazole, 48Microgynon. SeeEthinylestradiol +LevonorgestrelMicronor. SeeNorethisteroneMidazolam, 28Misoprostol. =prostaglanding E 1Modecate. See fluphenazineMonoclate-P. See factor VIIIMonozide. SeehydrochlorothiazideMorphine, 28, 29Multivitamin, 68Myambutol. See ethambutolMycostatin. See nystatinMyleran. See busulfanNalidixic acid, 36Naloxone, 31Naphazoline + Antazolineeye, 63Naphazoline eye, 62Naproxen, 29Natamycin eye, 61Neomycin + Bacitracin, 49Neostigmine, 60Nericur. See benzoylperoxideNeurobine. See Vitamins B1,B6, B12Nevimune. See nevirapineNevirapine, 42Niclosamide, 33Nifedipine, 46, 47Niopam. See iopamidolNitrocine. See glyceryltrinitrateNitrofurantoin, 36Nitronal. See glyceryltrinitrateNivaquine. See chloroquineNizoral. See KetoconazoleNoltam. See tamoxifenNonoxinol, 57Norcuron. See vecuroniumNordette. Seeethinylestradiol +levonorgestrelNordox. See doxycyclineNorethisterone, 56, 58Norethisterone-enantate, 56Norgestrel, 56Noriday. See NorethisteroneNorimin. See ethinylestradiol+ norethisteroneEritrean National List of Medicines 2010 Page 79

Noristerat. SeeNorethisterone-enantateNorplant. See Levonorgestrelreleasing implantNorvir. See ritonavirNVP. =nevirapineNystan. See nystatinNystatin, 38, 48, 52Ofloxacin, 38Ofloxacin eye, 61Omeprazole, 53Omnipaque. See iohexolOmsovist. See iotrolanOncovin. See vicristineOral rehydration salts, 55,66Oramorph. See morphineOrbenin. See cloxacillinOrgametril. See lynoestrenolORS, 55, 66ORS + Minerals, 69Ovrantte. SeeEthinylestradiol +LevonorgestrolOxygen, 27Oxytocin, 63Paludrin. See proguanilPanadol. See paracetamolPancuronium, 60Paracetamol, 29, 42Parkinane. See benzhexolParlodel. See bromocriptinePavulon. See pancuroniumPecram. See aminophyllinPedialyte. See ORS +mineralsPenadur. See benzathinbenzylpenicillinPenbritin. See ampicillinPencillin G. =BenzylpenicillinPenicillamine, 31Penicillin V. SeePhenoxymethyl pencillinPentamidine, 39, 40Pentostam. See sodiumstiboguluconatePentrexyl. See ampicillinPentrx. See coal tarPen-V-K. SeePhenoxymethyl pencillinPercutaneous. See BCGvaccinePermethrin, 50Pethidine, 28, 30Phenergan. SeepromethazinePhenobarbitone, 32Phenoxymethyl pencillin, 34Phenylephrine eye, 62Phenytoin, 32Phytomenadione, 45Pilocarpine eye, 62Pimperan. SeemetoclopramidePiperacillin, 34Eritrean National List of Medicines 2010 Page 80

Piriton. SeechlorpheniraminePlasil. See metoclopramidePlasma protein, 46Podophyllum resin, 49Poliomyelitis vaccine, 60Polygeline, 46Polymixin + Neomycin, 52Polymixin + Neomycin +Hydrocortisone, 52Portobulin. See anti-DimmunoglbulinPotassium chloride, 67Potassium ferrichexacyanoferrate, 31Potassium permanganate, 51Praziquantel, 33Prednisolone, 30, 44, 55Prednisolone eye, 61Prilosec. See omiprazolePrimaquine, 39Primolut N. SeenorethisteronePrimoteston. See testosteroneProcainamide, 47Procaine benzyl penicillin,34Procarbazine, 44Proguanil, 40Promethazine, 28, 53Propofol, 27Propranolol, 46, 47Propyliodone, 50Propylthiouracil, 58Prostaglaning E 1 , 63Prostigmin. See neostigmineProtamine, 45Provera. SeemedroxyprogesteronePyrazinamide, 37Pyridoxine hydrochloride,68Quinidine, 47Quinine, 39Rabies immunoglobulin, 59Rabies vaccine, 60Ranitidine, 53Remactane. See rifampicinReserpine, 47Resol. See ORS + mineralsRestandol. See testosteroneRetinol palmitate, 68Retrovir. See zidovudineRiboflavin, 69Rifadin. See rifampicinRifampicin, 36, 37Rifampicin + Isoniazid, 37Rifampicin+isoniazide+pyrazinamide, 37Ringer Lactate, 67Ritonavir, 42Rose Bengal, 50Rubella vaccine, 60Salbutamol, 63, 65Salicylic acid, 49, 52Eritrean National List of Medicines 2010 Page 81

Saquinavir, 42Schirmers’ test, 50Selenium sulfide, 48Senna, 54Sildenafil, 58Silver sulfadiazine, 49Simvastatin, 48Soda Lime, 27Sodium bicarbonate, 67Sodium chloride, 67Sodium citrate, 28Sodium edetate, 31Sodium fluoride, 69Sodium nitrite, 31Sodium phosphate rectal, 54Sodium stibogluconate, 39Sodium thiosulfate, 31Spectinomycin, 36Spironolactone, 51SQV, 42Stavir. See stavudineStavudine, 41Stavudine + Lamivudine, 20,41Stavudine + Lamivudine +Nevirapine, 42Streptomycin, 37Sulfadiazine, 36Sulfadoxine +Pyrimethamine, 40Sulfamethoxazole +trimethoprim, 36, 40Sulfasalazine, 54Sustiva. See efavirenzSuxamethonium, 60Tagamet. See cimetidineTamoxifen, 44Tegretol. See carbamazepineTenofovir, 42Tenormin. See atenololTerpoin. See CodeineTerra cortril. Seehydrocortisone +polymixin +oxytetracyclinTestosterone, 56, 58Tetanus antitoxin, 59Tetanus vaccine, 60Tetracaine eye, 62Tetracycline eye, 61Thiamine, 68Thioguanil, 43Thiopental sodium, 27Thioridazine, 64Thyroxine sodium. SeelevothyroxineTimolol eye, 62Timoptol. See timololTinidazole, 38Togamycin. SeespectinomycinTotamol. See atenololTramadol, 29Trandate. See labetalolTredemine. See niclosamideEritrean National List of Medicines 2010 Page 82

Trifluridine eye, 61Trivax. See Diphtheriapertussis-tetanusTrobicin. See spectinomycinTropicamide, 50Tryptizol. See amitriptylineTuberculin, proteinderivative, 58Tylenol. See paracetamolTyphoid vaccine, 60Unihep. See heparinUtovlan. See norethisteroneValium. See DiazepamValproic acid, 32Vascardin. See isosorbideVecuronium, 60Velbe. See vinblastineVentolin. See salbutamolVerapamil, 47Vermox. See mebendazoleVibramycin. See doxycyclineVidex. See didanosineVinblastine, 44Vincristine, 44Viramune. See nevirapineVitamin A. = retinolVitamin B, 68Vitamin B 1 . = thiamineVitamin B1, B6 and B12, 68Vitamin B 6 . = pyridoxineVitamin C. = ascorbic acidVitamin K. =phytomenadioneVogan. See retinolVolramin. See diclofencVoltaren. See diclofenacVoltarol. See diclofenacVominor. See meclozine +pyridoxineWarfarin, 45Water for injection, 67Whitfield. = benzoic acid +salcylic acidXylocaine. See LidocaineXylocard. See LidocaineXylometazoline, 52Yellow fever vaccine, 60Yomesan. See NiclosamideZerit. See stavudineZidovir. See zidovudineZidovudine, 41Zidovudine + Lamivudine,41Zigan. See abacavirZinamide. See pyrazinamidezinc sulfate, 21, 55Zinc sulphate, 67Zovirx. See AciclovirEritrean National List of Medicines 2010 Page 83