Guidelines for Iodine Prophylaxis following Nuclear Accidents

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WHO welcomes any feedback from readers in the form of commentsand experience with the application of these guideline sent to:Dr Keith BaverstockHelsinki Project Office for Nuclear Emergenciesand Public HealthLaippatie 400880 Helsinki, FinlandTel.: (+358) 9 759 88 780Fax: (+358) 9 759 88 682E-mail: keith.baverstock@who.fi
ContentsPagePreface ...............................................................................................iForeword...........................................................................................ii1. Introduction..................................................................................12. Radiation risk from radioactive iodine ..........................................22.1 Exposure to radioactive iodine ...............................................22.2 Deterministic and stochastic effects........................................32.3 Experience from the Chernobyl accident ................................42.4 Estimates of cancer risk .........................................................53. Stable iodine prophylaxis as a protective measure.........................73.1 The rationale for administration of stable iodine.....................73.2 Side effects from stable iodine: general considerations ...........73.3 Consideration of exposed population groups ..........................84. Implementation of stable iodine prophylaxis ...............................134.1 Intervention levels................................................................134.2 Balance between risk and benefit of taking stable iodine ......145. Considerations in planning the use of iodine prophylaxisin conjunction with other countermeasures................................155.1 Evacuation...........................................................................155.2 Sheltering ............................................................................165.3 Food control ........................................................................166. Logistics of stable iodine prophylaxis .........................................176.1 Chemical form.....................................................................176.2 Formulation, storage and packaging .....................................176.3 Availability, predistribution and distribution ........................186.4 Dosage and contraindications...............................................186.5 Timing of administration and duration of prophylaxis...............19Acknowledgments ..............................................................................23Annex 1 Half-lives of the important radioisotopes relatedto radioactive iodine found in fission products ................ 25Annex 2 Glossary of terms and acronyms ....................................... 24
Page 1 and 2: WHO/SDE/PHE/99.6English onlyDist.:
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Guidelines for Iodine Prophylaxis following Nuclear Accidents

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