7/18/2011 1 Clinical Use of Antiepileptic Drugs and Clinical Use of ...

7/18/2011Electroclinical syndromesarranged by age at onset• Neonatal period• Infancy• Childhood• Adolescence – Adult• Less specific age relationship19Electroclinical syndromesOnset at adolescence – adult• Juvenile absence epilepsy (JAE)• Juvenile myoclonic epilepsy (JME)• Epilepsy with generalized tonic–clonicseizures alone• Progressive myoclonus epilepsies(PME)• Autosomal dominant epilepsy withauditory features (ADEAF)• Other familial temporal lobe epilepsies20Distinctive constellations• Mesial temporal lobe epilepsy withhippocampal sclerosis• Rasmussen syndrome• Gelastic seizures with hypothalamichamartoma• Hemiconvulsion–hemiplegia–epilepsySeizures not diagnosed as epilepsy• Conditions with epileptic seizures that aretraditionally not diagnosed as a form ofepilepsy per se• Febrile seizure• Benign neonatal seizures (BNS)2122EXAMPLE23Example• ชาย อายุ 52 ปี มีอาการกระตุกที่แก้มข้างขวาก่อนแล้วจึงกระตุกทั ้งตัว หมดสติขณะที่กระตุกทั ้งตัว CT scan ofbrain พบ right frontal lobe tumor• Seizure type• Focal motor seizure at right faceevolving to a bilateral, convulsiveseizure• Epilepsy type• Epilepsy attributed to right frontal lobetumor244