Regional Postpartum Hemorrhage Guidelines
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• Recombinant factor VIIainduces hemostasis at thesite of injury.• The mechanism of actionincludes the binding offactor VIIa to the exposedtissue factor dependentpathway and, independentlyof tissue factor, activation offactor X directly on thesurface of activated plateletslocalized to the site ofinjuryRecombinant factor VIIa