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10th International Magnesium Symposium Schedule of Events

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3<br />

The influence <strong>of</strong> some antipsychotic drugs on erythrocyte and plasmatic<br />

magnesium level and <strong>of</strong> other bivalent cations<br />

M. Nechifor 1 , C. Vaideanu 1 , I. Palamaru 2 , C. Borza 3 , I. Mindreci 4 , 1.Department <strong>of</strong><br />

Pharmacology; 2.Institute <strong>of</strong> Hygiene Public Health; 3.Department <strong>of</strong> Psychiatry; 4.<br />

Department <strong>of</strong> Biophysics, Iasi, Romania. nechifor@umfiasi.ro<br />

The aim <strong>of</strong> the study was to investigate the influence <strong>of</strong> haloperidol (4-10 mg/day)<br />

and risperidone (Rispolept) (4-6 mg/day) on the plasmatic concentrations <strong>of</strong><br />

magnesium, calcium, copper and zinc, and on the erythrocyte magnesium level. We<br />

determined the cations levels before the hospitalized adult patients received any<br />

therapy and after 3 weeks <strong>of</strong> therapy. Our data indicate a lower erythrocyte<br />

magnesium in schizophrenics before treatment compared to the level found in<br />

controls (4,82±0,02 mg/dl in schizophrenic patients before treatment versus<br />

5,82±0,11 mg/dl in control group, p

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