NEWCASTLE DISEASE

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Stage 4 – Post vaccination trials • Laboratory trials # 1 • Unprimed and mat. Ab negative chicks - 120 • Primed with D58 • Sero-conversion studies • HI and ELISA • Serum collection – 0,7,14,21 PV and 7,14 PC • Four fold increase in serum antibody titre • Challenged with virulent NDV (obtained from IVPM) – 10 6 EID 50 • 100 % protection in vaccinated and varying mortality in control birds with exhibition of symptoms
Log HI titre Stage 5 – Post vaccination trials (Lab) Immune response in unprimed mat.Ab negative chicks 3 2.5 2 1.9115 2.3995 1.5 1 1 0.5 0 0 7 21 Days post vaccination Mean HI titre
Page 1 and 2: THERMOSTABLE VACCINE AGAINST NEWCAS
Page 3 and 4: Stages in development • Carried o
Page 5 and 6: Stage 2 - Thermostabilization • T
Page 7 and 8: Stage 2 - Thermostabilization • C
Page 9: Stage 3 - Production & Standardizat
Page 13 and 14: Stage 5 - Post vaccination trials (
Page 19 and 20: Mean OD Values Stage 5 - Post vacci
Page 21 and 22: Stage 5 - Genetic characterization
Page 27 and 28: Stage 6 - Field trials • Use of v
Page 29 and 30: Trial 1 Stage 6 - Field trials (Ind
Page 35 and 36: Trial-II Farm A Stage 6 - Field tri
Page 37 and 38: Stage 7 - Transfer of Technology
Page 39 and 40: Log 10 titre Immunity to turkeys RD
Page 41 and 42: Log 10 Titre Immunity to turkeys 6.
Page 43 and 44: Standardization of Vaccine • Foll
Page 45 and 46: Log titre Log2 Titre LOG titre Stag
Page 47 and 48: Post vaccination trials (field) •
Page 49 and 50: Summary • Developed a theromostab
Page 51: Acknowledgements • To the Tamil N

NEWCASTLE DISEASE

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