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NEWCASTLE DISEASE

Thermostable vaccines in India – John Kirubaharan - GALVmed

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Vaccine consumption pattern<br />

• Proventriculus<br />

• Lymphoid cell aggregation – 2 nd day<br />

• Mononuclear infiltration – 4 th day<br />

• Diffused lymphoid aggregation – 5 th day<br />

• Spleen<br />

• Increase in germinal centres – 2 nd day<br />

• Trachea<br />

• Mild hypertrophy – 6 th day<br />

• Lungs<br />

• Mild congestion with lymphoid aggregation – 2 nd day<br />

• Ileocaecal junction<br />

• Mild lymphoid depletion – 6 th day

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