Restriction Endonucleases Products (REP) Market - Global Industry Analysis And Forecast 2014 - 2020.pdf
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<strong>Restriction</strong> <strong>Endonucleases</strong> <strong>Products</strong><br />
(<strong>REP</strong>) <strong>Market</strong> - <strong>Global</strong> <strong>Industry</strong><br />
<strong>Analysis</strong>, Size, Share, Growth,<br />
Trends <strong>And</strong> <strong>Forecast</strong> <strong>2014</strong> - 2020<br />
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<strong>REP</strong>ORT DESCRIPTION<br />
<strong>Restriction</strong> enzymes or restriction endonucleases (RE) are the enzymes that are found in the bacteria and<br />
are harvested from them for their use in research and commercial aspects. These enzymes cut the<br />
deoxyribonucleotide (DNA) at specific nucleotide sequences and the biological function of these enzymes<br />
is to protect cells from foreign DNA . Nomeclature for these enzymes is based on the first letter of the<br />
genus followed by first two letters of the species and name of the bacteria of origin. These enzymes find<br />
applications in various research activities involving molecular biology techniques.<br />
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For instance, these enzymes are used as key reagents in processes such as restriction fragment length<br />
polymorphism (RFLP), genomic mapping, several recombinant procedures and DNA sequencing. There are<br />
four classes of restriction endonucleases namely types I, II, III and IV of which class II enzymes are the<br />
most popular and more useful as compared to others. The reason being the specific determination of the<br />
DNA sequences and generate termini with 5’ phosphate and 3’ hydroxyl groups and are capable of<br />
recognizing non-palindromic sequences. There has been continuous evolution of the new prototype<br />
activities that render continuous updates about new recognition sites along with the commercial<br />
availability. REBASE is such one database that provides monthly updates about the above mentioned<br />
factors.<br />
Till date more than 10,000 bacteria are screened for the presence of restriction enzymes and currently<br />
there are more than 2,500 restriction enzymes have been discovered along with over 250 distinct<br />
specificities in sequences. The microorganisms that produce RE also produce DNA methyltransferases and<br />
this feature protects their own DNA from cleavage.<br />
These enzymes are used in conventional cloning, deciphering epigenetic modifications, construction of<br />
DNA libraries and in vivo gene editing. The market for restriction endonucleases can be segmented by<br />
various types that are available commercially and the respective application areas. Companies such as<br />
New England Biolabs, Inc. and Thermo Fisher Scientific engage in development and marketing of various
types of restriction enzymes (A-Z). For instance, New England Biolabs, Inc. offers restriction enzymes in<br />
variable sizes such as 500 and 2,500 units. These units are priced at USD 57.00 for one unit. In addition,<br />
Thermo Fisher Scientific also offers these by FastDigest (176) brand and Conventional enzymes.<br />
Factors such as regulatory policies and product approvals govern the market growth. Furthermore, it can<br />
be classifies by the applications and end users. Pharmaceutical and biotechnology companies along with<br />
academic research institutes utilize these REs in various activities. Geographically, North America and<br />
Europe are the highest revenue generators in this market owing to increasing research and development<br />
activities followed by the presence of manufacturers in these regions. On the other hand Asia Pacific and<br />
Rest of the World (RoW) regions present lucrative opportunities for the growth of this market due to<br />
increasing research projects funding by the respective governments followed by increasing commercial<br />
production of these enzymes.<br />
There is a tremendous growth potential in acceptance of these enzymes owing to increasing<br />
implementation of molecular biology techniques and processes followed by increasing research and<br />
development activities making use of these enzymes. On the other hand, factors such as high cost of<br />
downstream activities coupled with variable reliability and accuracy of these enzymes are some factors<br />
that might restrain the market growth. Agilent Technologies, Inc., Genetix Biotech Asia Pvt. Ltd., New<br />
England Biolabs, Inc., ThermoFisher Scientific, Inc., and Promega Corporation are some of the key market<br />
players operating in this market.<br />
This research report analyzes this market on the basis of its market segments, major geographies, and<br />
current market trends. Geographies analyzed under this research report include<br />
• North America<br />
• Asia Pacific<br />
• Europe<br />
• Rest of the World
This report provides comprehensive analysis of<br />
• <strong>Market</strong> growth drivers<br />
• Factors limiting market growth<br />
• Current market trends<br />
• <strong>Market</strong> structure<br />
• <strong>Market</strong> projections for upcoming years<br />
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It<br />
provides market projections for the coming years. It includes analysis of recent developments in<br />
technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also<br />
includes a review of micro and macro factors essential for the existing market players and new entrants<br />
along with detailed value chain analysis.<br />
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