Restriction Endonucleases Products (REP) Market - Global Industry Analysis And Forecast 2014 - 2020.pdf

Restriction Endonucleases Products
(REP) Market - Global Industry
Analysis, Size, Share, Growth,
Trends And Forecast 2014 - 2020
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REPORT DESCRIPTION
Restriction enzymes or restriction endonucleases (RE) are the enzymes that are found in the bacteria and
are harvested from them for their use in research and commercial aspects. These enzymes cut the
deoxyribonucleotide (DNA) at specific nucleotide sequences and the biological function of these enzymes
is to protect cells from foreign DNA . Nomeclature for these enzymes is based on the first letter of the
genus followed by first two letters of the species and name of the bacteria of origin. These enzymes find
applications in various research activities involving molecular biology techniques.
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For instance, these enzymes are used as key reagents in processes such as restriction fragment length
polymorphism (RFLP), genomic mapping, several recombinant procedures and DNA sequencing. There are
four classes of restriction endonucleases namely types I, II, III and IV of which class II enzymes are the
most popular and more useful as compared to others. The reason being the specific determination of the
DNA sequences and generate termini with 5’ phosphate and 3’ hydroxyl groups and are capable of
recognizing non-palindromic sequences. There has been continuous evolution of the new prototype
activities that render continuous updates about new recognition sites along with the commercial
availability. REBASE is such one database that provides monthly updates about the above mentioned
factors.
Till date more than 10,000 bacteria are screened for the presence of restriction enzymes and currently
there are more than 2,500 restriction enzymes have been discovered along with over 250 distinct
specificities in sequences. The microorganisms that produce RE also produce DNA methyltransferases and
this feature protects their own DNA from cleavage.
These enzymes are used in conventional cloning, deciphering epigenetic modifications, construction of
DNA libraries and in vivo gene editing. The market for restriction endonucleases can be segmented by
various types that are available commercially and the respective application areas. Companies such as
New England Biolabs, Inc. and Thermo Fisher Scientific engage in development and marketing of various

types of restriction enzymes (A-Z). For instance, New England Biolabs, Inc. offers restriction enzymes in
variable sizes such as 500 and 2,500 units. These units are priced at USD 57.00 for one unit. In addition,
Thermo Fisher Scientific also offers these by FastDigest (176) brand and Conventional enzymes.
Factors such as regulatory policies and product approvals govern the market growth. Furthermore, it can
be classifies by the applications and end users. Pharmaceutical and biotechnology companies along with
academic research institutes utilize these REs in various activities. Geographically, North America and
Europe are the highest revenue generators in this market owing to increasing research and development
activities followed by the presence of manufacturers in these regions. On the other hand Asia Pacific and
Rest of the World (RoW) regions present lucrative opportunities for the growth of this market due to
increasing research projects funding by the respective governments followed by increasing commercial
production of these enzymes.
There is a tremendous growth potential in acceptance of these enzymes owing to increasing
implementation of molecular biology techniques and processes followed by increasing research and
development activities making use of these enzymes. On the other hand, factors such as high cost of
downstream activities coupled with variable reliability and accuracy of these enzymes are some factors
that might restrain the market growth. Agilent Technologies, Inc., Genetix Biotech Asia Pvt. Ltd., New
England Biolabs, Inc., ThermoFisher Scientific, Inc., and Promega Corporation are some of the key market
players operating in this market.
This research report analyzes this market on the basis of its market segments, major geographies, and
current market trends. Geographies analyzed under this research report include
• North America
• Asia Pacific
• Europe
• Rest of the World

This report provides comprehensive analysis of
• Market growth drivers
• Factors limiting market growth
• Current market trends
• Market structure
• Market projections for upcoming years
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It
provides market projections for the coming years. It includes analysis of recent developments in
technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also
includes a review of micro and macro factors essential for the existing market players and new entrants
along with detailed value chain analysis.
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