08.09.2015 Views

l’héparine Le risque est-il nul avec le fondaparinux ?

From Warkentin & Sheppard, 2006 - FMC de Tours

From Warkentin & Sheppard, 2006 - FMC de Tours

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T-cell<br />

B-cell<br />

Macromo<strong>le</strong>cular Comp<strong>le</strong>xes<br />

Plate<strong>le</strong>t<br />

FcγRIIa<br />

Heparin<br />

Plate<strong>le</strong>t factor 4<br />

HIT Antibodies<br />

Heparin neutralization<br />

Plate<strong>le</strong>t activation<br />

Re<strong>le</strong>ase of PF4<br />

FVIIa<br />

Activation of<br />

monocytes<br />

Thrombin<br />

Procoagulant<br />

Microparticu<strong>le</strong>s<br />

FVIIa<br />

Tissue Factor<br />

Heparan sulphate<br />

Endothelial cells

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