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ENT<br />

BrainLAB’s remarkable growth and success are attributed to its<br />

employees. Since the company’s beginning, BrainLAB has placed<br />

its first and greatest emphasis on hiring tal<strong>ent</strong>ed, dedicated and<br />

visionary employees.<br />

YOUR PARTNER FOR THE FUTURE<br />

BrainLAB is a company based in Munich, Germany, that develops,<br />

manufactures, and markets software-driven medical equipm<strong>ent</strong>.<br />

BrainLAB’s products allow physicians to provide treatm<strong>ent</strong><br />

that improves medical outcomes while being more accurate, less<br />

invasive, and less expensive than traditional surgery. For over 13<br />

years, BrainLAB has been the leading innovator in the fields of<br />

image-guided surgery and stereotactic radiosurgery. Today the<br />

company has offices in thirteen countries and employs well over<br />

400 people. BrainLAB’s core competency is integrating userfriendly<br />

software into surgical procedures. By simplifying complex<br />

technologies to fit all surgeons’ needs, BrainLAB is able to offer<br />

superior software solutions to all customers. In addition, BrainLAB<br />

can implem<strong>ent</strong> new ideas fast and effici<strong>ent</strong>ly by leveraging its<br />

curr<strong>ent</strong> technology base. BrainLAB’s success has been built on<br />

innovative technologies along with reliable 24-hour service, and<br />

a 100% focus on customers’ needs.<br />

BrainLAB’s products for image-guided surgery have found<br />

broad acceptance at more than 550 institutions worldwide,<br />

including large university hospitals and private clinics as well as<br />

smaller regional community hospitals and surgical c<strong>ent</strong>ers.<br />

01


ENT<br />

02<br />

Joseph Doyle, Stefan Vilsmeier, Rainer Birkenbach<br />

1<br />

THE DRIVE BEHIND OUR PRODUCTS<br />

BrainLAB, located in Munich, Germany, is a think tank where over<br />

100 engineers strive toward the same goal: to make BrainLAB<br />

the leading provider of software for minimally invasive therapies<br />

in a variety of medical sub-specialties.<br />

In order to accomplish this, we have created a high-tech environm<strong>ent</strong><br />

in which employees from all over the world can generate<br />

the most creative solutions.<br />

1�BrainLAB’s general managem<strong>ent</strong> has been with the company<br />

since its early days. Stefan Vilsmeier, Presid<strong>ent</strong> and CEO (c<strong>ent</strong>er),<br />

Joseph Doyle, CFO (left), and Rainer Birkenbach, Executive<br />

Vice Presid<strong>ent</strong> Research and Developm<strong>ent</strong> (right), each have<br />

extensive experience within the medical industry and with<br />

BrainLAB. Once operating out of a one-room office, BrainLAB<br />

now occupies a large office complex and is viewed as a global<br />

leader in medical technology.<br />

2�Quality assurance is ess<strong>ent</strong>ial in developing and marketing<br />

the most innovative software-driven medical equipm<strong>ent</strong> available<br />

today. At BrainLAB, every step of the process is overseen to<br />

ensure the highest standards of German engineering are met. It<br />

is these standards along with ISO 9001/13485 certification that<br />

guarantee BrainLAB will continue to deliver the highest quality<br />

products to our customers.<br />

3�Rapid prototyping, speed of product developm<strong>ent</strong>, and short<br />

time to market have all been critical elem<strong>ent</strong>s in BrainLAB’s success.<br />

BrainLAB has remained on the cutting edge by being able to<br />

quickly implem<strong>ent</strong> new ideas. Rainer Birkenbach, Executive Vice<br />

Presid<strong>ent</strong> of Research and Developm<strong>ent</strong>, ensures all products are<br />

strictly monitored from their developm<strong>ent</strong>al stage to completion.<br />

2


3<br />

4�Today’s pati<strong>ent</strong>s are becoming increasingly educated as to<br />

what the most advanced treatm<strong>ent</strong> methods are and where they<br />

must go to receive them. Therefore, it is our policy to comprehensively<br />

support our customers with marketing programs for<br />

pati<strong>ent</strong>s that will help drive their institutions’ economic success.<br />

5�Training programs are held on a regular basis throughout<br />

BrainLAB. It is extremely important that all employees are fully<br />

trained in many aspects of our business. Since BrainLAB enjoys<br />

such a large growth rate, continuous training is ess<strong>ent</strong>ial in<br />

assuring constant organizational evolution is carried out flawlessly<br />

and the company culture is maintained.<br />

6�Stefan Vilsmeier founded the company in 1989 and he still<br />

talks with more than 1,000 customers every year. This is indicative<br />

of the constant customer interaction that has made BrainLAB<br />

what we are today and determines where we will be in the future.<br />

5<br />

4<br />

6<br />

03


ENT<br />

04<br />

“Cutting-edge technology for image guidance in sinus<br />

surgery. That’s why we chose BrainLAB.” Br<strong>ent</strong> Senior, M.D.,<br />

FACS, Associate Professor Otolaryngology/Head and Neck Surgery;<br />

Chief, Rhinology and Sinus Surgery, University of North Carolina, USA<br />

“Image-guided FESS should make complex FESS cases easier<br />

for the surgeon, hospital staff, and pati<strong>ent</strong> - the BrainLAB<br />

<strong>system</strong> is doing that for us.”<br />

Dr. Winston Vaughan, Director of Stanford Sinus C<strong>ent</strong>er, USA<br />

“BrainLAB offers the greatest flexibility and ease of use when<br />

it comes to instrum<strong>ent</strong>ation, data transfer and OR setup of<br />

any IGS <strong>system</strong> for sinus and skull base surgery.”<br />

Rodney Schlosser, M.D., Assistant Professor, Director of Rhinology/ Sinus<br />

Surgery, Medical University of South Carolina, USA<br />

BRAINLAB’S INTERNATIONAL PRESENCE<br />

At BrainLAB, customer participation in product developm<strong>ent</strong> is<br />

ess<strong>ent</strong>ial. Our goal is to continue to establish privileged relationships<br />

with opinion-leading physicians throughout the world. Below are a<br />

few of our key physician partners in the field of otorhinolaryngology.<br />

Over 550 image-guided surgery sites worldwide have selected<br />

BrainLAB as their IGS company of choice in the fields of ENT,<br />

neurosurgery, and orthopedic surgery. Because of our rapidly<br />

increasing image-guided <strong>system</strong> market share and desire to optimize<br />

all products and processes, BrainLAB has initiated customer<br />

satisfaction surveys. This third party survey* found that<br />

VectorVision customers use their IGS <strong>system</strong>s more than twice<br />

as much as any of our competitors. In addition, BrainLAB’s<br />

VectorVision <strong>system</strong>s enjoy the highest uptime perc<strong>ent</strong>age of all<br />

IGS <strong>system</strong>s. With one of the highest service engineer to customer<br />

ratios, BrainLAB service engineers are able to reach over<br />

90% of all customers within a very short time. With the upcoming<br />

introduction of BrainLAB’s web-based i Help�, customer service<br />

will be taken to the next level. iHelp enables BrainLAB’s customers<br />

to instantly communicate with a BrainLAB Service<br />

Engineer directly from the OR using the integrated web camera<br />

installed on their image-guided <strong>system</strong>.<br />

*Health IQ<br />

“We evaluated all available image-guided surgery <strong>system</strong>s on<br />

the market and BrainLAB delivered the most user-friendly,<br />

technologically advanced <strong>system</strong> available today.”<br />

Robert Bonham, M.D., P.A. Diplomat, American Board of Otolaryngology,<br />

Consultant for Tenet Healthcare, Dallas, USA<br />

“The fast and easy setup of the <strong>system</strong>, the intuitive user<br />

interface and the high intra-operative precision make<br />

VectorVision� one of the most advanced image-guided<br />

surgery <strong>system</strong>s available. The posssibility of integrating preexisting<br />

instrum<strong>ent</strong>s, surgical endoscopes and microscopes<br />

complem<strong>ent</strong> the superior product.”<br />

Prof. Dr. Bernd Freigang, Director, Departm<strong>ent</strong> of Otolaryngology,<br />

Head and Neck Surgery Medical School, Otto-von-Guericke-<br />

University, Magdeburg, Germany


MAP LEGEND<br />

VectorVision �<br />

Service Engineer<br />

BRAINLAB REFERENCE SITES 2003<br />

�University of North Carolina, Chapel Hill, NC, USA<br />

�Medical University of South Carolina, Charleston, SC, USA<br />

�Hospital of the University of Pennsylvania, PA, USA<br />

�Sherman Hospital, Chicago, IL, USA<br />

�Stanford University Medical C<strong>ent</strong>er, Stanford, CA, USA<br />

�Danbury Hospital, Danbury, CT, USA<br />

�RHD Hospital, Dallas, TX, USA<br />

�Lewisville Hospital, Lewisville, TX, USA<br />

�Harris Methodist, Bedford, TX, USA<br />

�North Iowa Med C<strong>ent</strong>er, Mason City, IA, USA<br />

�Delnore Hospital, Elgin, IL, USA<br />

�Baptist Medical C<strong>ent</strong>er, Kansas City, MO, USA<br />

�East Cooper Regional, Mt. Pleasant, SC, USA<br />

�Universität München, Großhadern, Germany<br />

�Medizinische Hochschule Hannover, Hannover, Germany<br />

�Universitätsklinik Tübingen, Tübingen, Germany<br />

�Johann-Wolfgang-Goethe University, Frankfurt, Germany<br />

�Klinikum rechts der Isar, München, Germany<br />

�Z<strong>ent</strong>rum für Zahn-, Mund-, Kieferheilkunde, Köln, Germany<br />

�Bundeswehrkrankenhaus Ulm, Ulm, Germany<br />

�Klinikum Starnberg, Starnberg, Germany<br />

�Universitätsklinik Hamburg-Eppendorf, Hamburg, Germany<br />

�Evangelisches Krankenhaus Oldenburg, Oldenburg, Germany<br />

�Universitätsspital Zürich, Zürich, Switzerland<br />

�Queen Mary Hospital, Hong Kong, PRC<br />

�Tuen Mun Hospital, Hong Kong, PRC<br />

�Hôpital Edouard Herriot, Lyon, France<br />

�Hôpital Lyon Sud, Lyon, France<br />

�Hôpital La Citadelle, Liège, Belgium<br />

�Fundación Hospital Son Llàtzer, Palma de Mallorca, Spain<br />

�Beijing Tongren Hospital, Beijing, PRC<br />

�Xian Xijing Hospital, Xian, PRC<br />

�Gifu Prefectual Hospital, Gifu, Japan<br />

�Tokai University Hachioji Hospital, Tokyo, Japan<br />

05


ENT<br />

06<br />

BENEFITS OF IMAGE-GUIDED SURGERY<br />

CLINICAL BENEFITS The clinical benefits associated with<br />

image-guided surgery (IGS) continue to drive its acceptance and<br />

growth worldwide. IGS assists surgeons in performing less invasive<br />

surgeries through smaller incisions and direct access to<br />

specific targeted areas. Because image guidance promotes less<br />

invasive surgery, pati<strong>ent</strong>s in turn benefit. With BrainLAB <strong>system</strong>s<br />

being fully integrated into virtually any operating room via endoscope,<br />

microscope, ultrasound, and fluoroscope, the OR provides<br />

a complete surgical solution.<br />

FINANCIAL BENEFITS As medical technology advances, health<br />

care professionals are under increased pressure to improve the<br />

quality of health care as well as contain costs. Therefore, comprehensive<br />

knowledge of proper procedural billing and coding is<br />

ess<strong>ent</strong>ial when purchasing high-tech medical equipm<strong>ent</strong> such as<br />

image-guided surgery. Since reimbursem<strong>ent</strong> is becoming<br />

increasingly important for maximizing return on investm<strong>ent</strong>, it is<br />

a requirem<strong>ent</strong> to have access to the most curr<strong>ent</strong> coding procedures<br />

and laws. For this reason, BrainLAB has put a team of<br />

experts, dedicated to handling all reimbursem<strong>ent</strong> questions, at our<br />

customers’ disposal. A Reimbursem<strong>ent</strong> Help-Line further<br />

enhances our customer service.<br />

In addition, multiple software applications such as ENT,<br />

cranial, spine, knee, hip, and trauma can be installed on the<br />

same <strong>system</strong>. The <strong>system</strong> can be used in multiple departm<strong>ent</strong>s<br />

throughout the hospital, thus increasing cost-efficiency.


ENT<br />

08<br />

VECTORVISION ® ENT PROCEDURE<br />

PATIENT REGISTRATION<br />

1�Select laser registration mode<br />

2�Scan surface with z-touch�<br />

laser pointer<br />

3�Verify registration accuracy


PATIENT IMAGING During diagnostic imaging, the pati<strong>ent</strong> is not<br />

required to wear a headset or fiducial markers. The scan is taken<br />

with a standard CT/MR protocol that ensures the optimum accuracy<br />

and resolution required for image-guided surgery. Because<br />

the CT/MR scan requires no headset or fiducial markers, the<br />

need for an additional scan once required to perform image-guided<br />

surgery is eliminated. This allows the surgeon to navigate<br />

within his/her original diagnostic imaging scan, thus reducing<br />

radiation exposure to the pati<strong>ent</strong>.<br />

ATTACHMENT OF THE REFERENCE HEADBAND BrainLAB’s<br />

Reference Headband is designed for usage in ENT and cranial<br />

navigation cases. The headband ensures dynamic pati<strong>ent</strong> tracking<br />

throughout the case and eliminates the need for invasive pati<strong>ent</strong><br />

immobilization or uncomfortable headsets. BrainLAB’s flexible<br />

VELCRO�- band adjusts smoothly to the pati<strong>ent</strong>’s head and fits all<br />

pati<strong>ent</strong> sizes. The innovative design avoids intra-operative shift and<br />

guarantees navigational accuracy throughout surgery.<br />

PATIENT REGISTRATION z-touch� laser registration forms<br />

the basis of BrainLAB’s headset-free scanning and registration.<br />

z-touch is a special laser pointer that allows to utilize each pati<strong>ent</strong>’s<br />

head and facial anatomy for registration. Once the pati<strong>ent</strong>’s facial or<br />

head surface is randomly scanned, BrainLAB’s advanced surfacematching<br />

algorithm quickly calculates pati<strong>ent</strong> registration.<br />

Physicians are able to accurately register pati<strong>ent</strong>s without using<br />

pati<strong>ent</strong> markers or headsets. Calculation errors, which may occur<br />

through landmark-point coordination, are therefore eliminated.<br />

INSTRUMENT CALIBRATION With BrainLAB’s redesigned<br />

instrum<strong>ent</strong> calibration matrix (ICM), the tip of extremely b<strong>ent</strong> or<br />

curved instrum<strong>ent</strong>s can easily be calibrated for use in navigation.<br />

Calibration is quickly achieved by affixing the desired instrum<strong>ent</strong><br />

with one of BrainLAB’s wireless instrum<strong>ent</strong> adaptor clamps and<br />

then touching the tip of the surgical instrum<strong>ent</strong> to one of the two<br />

pivot points on the ICM. The software automatically calculates<br />

the exact location of the instrum<strong>ent</strong>’s tip and the instrum<strong>ent</strong> is<br />

ready for navigation. In addition, the instrum<strong>ent</strong>’s shape and<br />

diameter can also be calibrated by inserting the shaft of the<br />

instrum<strong>ent</strong> into the holes of the ICM.<br />

09


ENT<br />

SET UP DISPLAY<br />

Simultaneous display of<br />

multiple views on the<br />

monitor, e.g. axial, sagittal,<br />

coronal, inline and<br />

3D as well as live images<br />

from endoscope, microscope,<br />

or ultrasound.<br />

PRE-DEFINED<br />

SETTINGS<br />

Pre-defined screen<br />

setups optimized for<br />

individual ENT procedures<br />

available at the<br />

touch of a finger.<br />

REGISTRATION<br />

SELECTION<br />

Multiple registration<br />

methods such as laser,<br />

marker, or landmark<br />

enable the user to<br />

achieve an accurate registration<br />

in a wide variety<br />

of situations and cases.<br />

10<br />

VECTORVISION ® ENT SYSTEM<br />

The VectorVision ENT <strong>system</strong> provides surgeons with the widest range of ENT image-guided surgical capabilities<br />

available and thus makes the <strong>system</strong> adaptable to the most demanding clinical situations. The <strong>system</strong><br />

instantly enables wireless tracking of pre-existing surgical instrum<strong>ent</strong>s and gives the surgeon full control via the<br />

touchscreen monitor. Additional optional features include Advanced 3D, Image Fusion, MRI and Microscope<br />

Integration. VectorVision ENT is a highly sophisticated <strong>system</strong> designed for the most demanding user.<br />

TOOLBOX<br />

A collection of advanced software<br />

features, including measurem<strong>ent</strong><br />

function, trajectory planning,<br />

integration of live endoscopic<br />

view, microscope and ultrasound,<br />

as well as 3D display<br />

options, is stored in the toolbox.<br />

MULTIPLE IMAGE MODALITIES<br />

Integration of multiple diagnostic<br />

data (CT, MRI, PET, SPECT,<br />

CT Angio, MR Angio) with various<br />

display options on the<br />

VectorVision screen.


VECTORVISION CAMERAS The VectorVision cameras are the<br />

core unit of the tracking <strong>system</strong>. BrainLAB proprietary tracking<br />

software algorithms make the underlying Northern Digital Inc.<br />

technology the most reliable and accurate passive marker <strong>system</strong><br />

available.<br />

VECTORVISION TOUCHSCREEN No mouse, no keyboard,<br />

no hassle — the VectorVision touchscreen puts the physician in<br />

complete control of the image-guided <strong>system</strong>. The ergonomic<br />

design and arrangem<strong>ent</strong>s of software buttons make it a fully<br />

integrated <strong>system</strong>. Spring-loaded arms and a custom-fit sterile<br />

drape allow flexible and safe positioning of the touchscreen<br />

close to the surgical field.<br />

PASSIVE MARKER TECHNOLOGY Passive marker technology<br />

was pioneered by BrainLAB in 1996 and since then has set the<br />

standard in instrum<strong>ent</strong> tracking. With passive markers, attaching<br />

cumbersome wires and/or LED lights to instrum<strong>ent</strong>s is no longer<br />

necessary. Virtually any pre-existing surgical instrum<strong>ent</strong> is<br />

instantly integrated into the surgical procedure.<br />

BASIC VECTORVISION TECHNOLOGY<br />

� Touchscreen and<br />

cameras in storage position<br />

� Small footprint<br />

� User panel: Connectivity to the<br />

network, microscopes, c-arm,<br />

and other video sources<br />

� Internal BUS <strong>system</strong> enables<br />

future hardware upgrades<br />

� ZIP-Drive<br />

� On/Off Switch<br />

� Brake pedal to lock the wheels<br />

� Robust metal cover<br />

11


ORTHO ENT<br />

12<br />

KOLIBRI ENT SYSTEM<br />

The Kolibri <strong>system</strong> was designed with the goal of making image-guided surgery available to every pati<strong>ent</strong>. Since Kolibri<br />

ENT is compact and affordable it is ideal for surgery c<strong>ent</strong>ers and for hospitals with smaller case loads or hospitals in<br />

need of additional treatm<strong>ent</strong> capacity. The <strong>system</strong>’s lightweight portable design makes it easy to move between multiple<br />

facilities. With the ability to track pre-existing surgical instrum<strong>ent</strong>s, to display live endoscopic video, and to control the<br />

<strong>system</strong> via the touchscreen monitor, Kolibri’s integration into the surgical procedure is straightforward. Driven by<br />

BrainLAB’s user-friendly software, the learning curve of the <strong>system</strong> is extremely short.<br />

LOADING OF PATIENT DATA Pati<strong>ent</strong> data will be automatically<br />

loaded upon data transfer completion. Using the hospital’s network<br />

connection and the universal DICOM format, the new software<br />

PatXfer assures a simple and time-saving data transfer.<br />

Data on the scanner can be accessed and easily retrieved.<br />

PATIENT SETUP BrainLAB’s Reference Headband is attached<br />

to the pati<strong>ent</strong>’s head ensuring dynamic tracking throughout the<br />

case and eliminating the need for invasive pati<strong>ent</strong> immobilization<br />

and uncomfortable headsets. This dynamic reference device<br />

allows for unpreced<strong>ent</strong>ed freedom of movem<strong>ent</strong> during navigation<br />

while maintaining a high degree of accuracy.<br />

PATIENT REGISTRATION Equipped with the standard wireless<br />

Softouch pointer the pati<strong>ent</strong> is easily registered within seconds.<br />

The pointer uses a sensitive tip to detect the surface points on<br />

the pati<strong>ent</strong>’s skin. For additional intra-operative registration, other<br />

methods such as the z-touch� laser are also compatible with the<br />

<strong>system</strong>.<br />

NAVIGATION The Kolibri ENT interface guides the surgeon<br />

through the procedure and provides continuous information on<br />

instrum<strong>ent</strong> position and movem<strong>ent</strong> in multiple planes.<br />

Simultaneously, a real-time endoscopic view can be displayed on<br />

the navigation screen.


KOLIBRI FEATURES<br />

� Portable design for use in multiple ORs<br />

�Touchscreen monitor for simple <strong>system</strong> control<br />

�Wireless tracking of instrum<strong>ent</strong>ation<br />

�Instant integration of pre-existing surgical instrum<strong>ent</strong>s<br />

�Real-time endoscopic video display<br />

�Mobile camera stand for optimal positioning<br />

�Network connectivity and CD-writer, both standard<br />

�Dimensions: 457 x 410 x 355mm<br />

�Weight: 16 kg (30 pounds)<br />

KOLIBRI CAMERA STAND<br />

13


ENT<br />

14<br />

VECTORVISION ® ACCESSORIES<br />

BrainLAB offers a wide variety of accessories, which complem<strong>ent</strong> the VectorVision ENT and Kolibri ENT<br />

image-guided surgery <strong>system</strong>s. With BrainLAB’s industry-leading, pat<strong>ent</strong>ed passive marker technology, the<br />

surgeon can navigate instrum<strong>ent</strong>s with an unequalled degree of freedom. The wireless design eliminates<br />

cables, foot switches, and other restricting electronics. Each hardware compon<strong>ent</strong> and accessory is highly<br />

refined and engineered for optimum efficiency, durability, and ease of use.<br />

POINTERS The universal VectorVision instrum<strong>ent</strong>, the Pointer, can<br />

be used for multiple tasks, from pati<strong>ent</strong> registration and accuracy<br />

verification to navigation for surgical resections. VectorVision<br />

Pointers are lightweight, durable and available both sharp- and<br />

blunt-tipped, depending on the specific surgical requirem<strong>ent</strong>s. The<br />

passive markers are attached to the Pointer via simple threads, and<br />

ensure almost unlimited maneuverability, minimizing line of sight<br />

issues. BrainLAB’s reflective marker spheres can be purchased as<br />

pre-sterilized disposables or re-sterilizable for repeated use.<br />

INSTRUMENT ADAPTERS With BrainLAB’s passive marker<br />

instrum<strong>ent</strong> adapter clamps, virtually any pre-existing ENT instrum<strong>ent</strong><br />

– such as blakesly forceps, suction, microdebreeders, and<br />

curettes can be integrated into the procedure. The small, lightweight<br />

adapter clamps are easily attached via a thumbscrew and<br />

stay rigidly affixed throughout the case. Due to the unlimited ability<br />

to interchange the differ<strong>ent</strong>ly sized clamps and arrays, the surgeon<br />

has access to the right instrum<strong>ent</strong> at the right time.<br />

INSTRUMENT CALIBRATION MATRIX (ICM) In addition to an<br />

instrum<strong>ent</strong> tip calibration, BrainLAB offers an easy, fast, and accurate<br />

calibration of instrum<strong>ent</strong> diameter and vector. Within seconds,<br />

BrainLAB’s ICM integrates uniquely shaped instrum<strong>ent</strong>s such as<br />

frontal sinus probes and suctions. The ICM expands the range of<br />

instrum<strong>ent</strong>ation, which can be incorporated into navigated surgery.<br />

SKULL REFERENCE ARRAY BrainLAB’s bone-anchored<br />

Reference Star has been developed for usage in surgeries of the<br />

lateral skull base and other complex ENT/neurosurgical procedures.<br />

This dynamic reference device allows for unpreced<strong>ent</strong>ed<br />

freedom of movem<strong>ent</strong> during navigation while maintaining<br />

BrainLAB’s high degree of accuracy. The Skull Reference Array<br />

is a minimally invasive device that is directly attached to the<br />

outer skull with a small self-taping screw. Three support pins stabilize<br />

the fixation of the base. Since the surgeon does not have<br />

to rely on fixed reference units like the Mayfield Clamp the head<br />

of the pati<strong>ent</strong> can be moved freely during surgery to provide better<br />

access to the areas of interest.


IMAGE COMPOSER BrainLAB’s Image Composer opens a new<br />

dimension in the intra-operative visualization of diagnostic<br />

images. Multi-modality image data can be merged into one unified<br />

image. Information is automatically extracted and displayed<br />

in this new image set to optimize the visualization of preferred<br />

structures such as bone, vessel, and tissue, making all relevant<br />

data available at a glance. Image Composer is the ideal software<br />

package for the otolaryngologist who performs surgical procedures<br />

at the skull base.<br />

MICROSCOPE INTEGRATION VectorVision Microscope<br />

Integration increases the functionality of the navigation <strong>system</strong><br />

and microscope, while at the same time optimizing the workflow<br />

of both applications. By easily attaching BrainLAB’s specially<br />

designed microscope adapter the microscope can be used to<br />

navigate within a matter of seconds. Intellig<strong>ent</strong> features such as a<br />

virtual pointer, image injection and video display ensure that the<br />

surgeon receives the best visual information when integrating a<br />

microscope into the navigation <strong>system</strong>.<br />

IGS-READY POINTER INSTRUMENTS The newly designed<br />

pointer instrum<strong>ent</strong> set provides surgeons with a number of various<br />

interchangeable tip shapes, ensuring maximum navigation flexibility<br />

while maintaining high intra-operative precision throughout<br />

surgery. The surgeon has the freedom to choose whatever tip is<br />

appropriate for the scheduled indication.<br />

The tips can be aligned and fixed in eight differ<strong>ent</strong> ori<strong>ent</strong>ations<br />

making it easy to adjust the instrum<strong>ent</strong> to the surgical setting. The<br />

probe has an integrated StarLink interface for the adaptation and<br />

wireless tracking of the pointer in combination with an Instrum<strong>ent</strong><br />

Adapter Array.<br />

IGS-READY SUCTION Standard suction devices are equipped<br />

with the new StarLink interface providing the highest navigation<br />

accuracy possible. Once the adaptor clamp is attached, calibration<br />

is performed instantly.<br />

15


ENT<br />

PATIENT HISTORY The pati<strong>ent</strong>, a 42-year-old female with a history<br />

of motor vehicle accid<strong>ent</strong>, in which she suffered severe<br />

frontal and naso-facial trauma. This included severely comminuted<br />

frontal sinus facture and naso-orbito-ethmoid fracture. This was<br />

repaired with extensive frontal bone and trans-nasal wiring. Ten<br />

years later the pati<strong>ent</strong> developed Pott’s puffy tumor. This was<br />

managed by a prolonged course of antibiotics, and endoscopic<br />

drainage of the frontal recess and frontal sinus to the midline utilizing<br />

a drill (Draf IIB procedure). At the time of the procedure,<br />

16<br />

CHRONIC FRONTAL SINUSITIS WITH COMPLICATED<br />

ANATOMY<br />

Fig.1 Fig.2<br />

Fig.3 Fig.4<br />

VECTORVISION ® CASE REPORTS<br />

the frontal recess exposure was carried to the limits of the<br />

instrum<strong>ent</strong>ation, but an area of neo-osteogenesis and narrowing<br />

remained laterally. Postoperatively, the inflammation was noted<br />

to dramatically improve and the pati<strong>ent</strong> became and remained<br />

asymptomatic. However, over the subsequ<strong>ent</strong> years the pati<strong>ent</strong><br />

developed endoscopic evidence of bony closure of the communication<br />

to the lateral portion of the frontal sinus.<br />

This endoscopically diagnosed bony stenosis of the lateral aspect<br />

of the frontal recess was confirmed by CT imaging, which also<br />

demonstrated the extensive hardware pres<strong>ent</strong> from her previous<br />

injury. Notably, the lateral portion of the right frontal sinus was<br />

opacified, and this area was closed off from the remaining sinus<br />

cavity and frontal recess by neo-osteogenic foci. On preoperative<br />

endoscopy, normal landmarks could not be visualized in light of the<br />

pati<strong>ent</strong>’s previous trauma and surgery.<br />

TREATMENT Endoscopic frontal sinusotomy with removal of the<br />

obstructing bone was recommended, and the pati<strong>ent</strong> cons<strong>ent</strong>ed to<br />

proceed. Stereotactic navigational imaging was obtained using the<br />

BrainLAB protocol. Endoscopically, two depressions were visualized<br />

within the pot<strong>ent</strong>ial frontal drainage tract (Fig.1). Intra-operative<br />

navigational imaging using the BrainLAB VectorVision ENT <strong>system</strong><br />

demonstrated the more medial recess to be the skull base (Fig.2),<br />

while the lateral recess correlated with the likely drainage pathway<br />

(Fig.3). These determinations were visualized in three dimensions.<br />

Using a combination of markedly angled, powered diamond<br />

burrs, frontal recess curettes, and forceps with angles designed<br />

for frontal sinus surgery, sinusotomy was performed. Thick bone<br />

was removed. A curved suction equipped with a BrainLAB<br />

instrum<strong>ent</strong> adaptor clamp was calibrated and passed into the<br />

sinus, confirming patency in three dimensions (Fig.4).<br />

CONCLUSION Throughout the procedure, because of the optical<br />

referencing of the <strong>system</strong>, no accuracy problems were encountered<br />

secondary to the metallic hardware pres<strong>ent</strong> in the surgical<br />

vicinity. Postoperatively, the pati<strong>ent</strong> has done well, with excell<strong>ent</strong><br />

trans-illumination of the sinus observed during office endoscopy.<br />

David W. Kennedy, M.D.,<br />

Rakesh K. Chandra, M.D., and James N. Palmer, M.D.<br />

Hospital of the University of Pennsylvania


MINIMALLY-INVASIVE PITUITARY SURGERY (MIPS)<br />

Fig. 1<br />

Fig. 3<br />

Fig. 2<br />

MINIMALLY-INVASIVE PITUITARY SURGERY (MIPS)<br />

PATIENT HISTORY A 56-year-old man was found confused in<br />

the local park. On pres<strong>ent</strong>ation to the emergency room, he was<br />

found to be ori<strong>ent</strong>ed to person and place, but not time.<br />

Toxicology screening was normal. MRI of the head was obtained<br />

with findings of a large compressing mass of the sella with v<strong>ent</strong>ricular<br />

enlargem<strong>ent</strong> (Fig. 1) consist<strong>ent</strong> with a large pituitary adenoma.<br />

TREATMENT He was taken to the operating room where endoscopic<br />

resection of the sellar tumor was performed via minimallyinvasive<br />

pituitary surgery (MIPS) technique. Image guidance<br />

utilizing BrainLAB VectorVision was utilized to assist in the resection.<br />

The head was not pinned, being allowed to move freely using<br />

the adjustable headband reference array for head localization<br />

while using the <strong>system</strong>. Registration was performed utilizing the<br />

touchless z-touch� registration technique. Instrum<strong>ent</strong>s, including<br />

angled open curettes, were tracked actively during the surgery,<br />

allowing for real-time assessm<strong>ent</strong> of instrum<strong>ent</strong> position (Fig. 2).<br />

This allowed maximum tumor resection while minimizing risk to<br />

the pati<strong>ent</strong>.<br />

CONCLUSION No CSF occurred. Pathologic examination<br />

revealed pituitary adenoma. Post-op MRI shows very complete<br />

tumor resection (Fig. 3).<br />

Br<strong>ent</strong> Senior, M.D., FACS<br />

Associate Professor Otolaryngology/Head and Neck Surgery<br />

University of North Carolina<br />

17


ENT<br />

VectorVisioncompact<br />

18<br />

Kolibri m 3<br />

Novalis<br />

BRAINLAB’S PRODUCTS<br />

BrainLAB offers a large and diversified portfolio of unique and superior products for various medical subspecialties.�Image-guided<br />

surgery enables the physician to track the position of a surgical instrum<strong>ent</strong> or implant<br />

to guide it safely and precisely to its target.�Radiosurgery enables the non-invasive treatm<strong>ent</strong> of various<br />

tumors using focused radiation.<br />

VectorVision 2<br />

ExacTrac X-ray<br />

VECTORVISION� CRANIAL With VectorVision cranial, neurosurgeons<br />

have the ability to track the position of virtually any surgical<br />

instrum<strong>ent</strong> equipped with BrainLAB’s passive markers. Instrum<strong>ent</strong>s<br />

are continuously visualized relative to pre-operative diagnostic<br />

images, giving surgeons the ability to see beyond the surface of<br />

the surgical field using computer renderings. VectorVision cranial<br />

provides safer and less invasive access to brain tumors, vascular<br />

abnormalities, and other intra-cranial targets by minimizing the<br />

size of craniotomies.<br />

VECTORVISION� SPINE VectorVision spine gives surgeons<br />

the ability to interactively select the ideal size and 3-dimensional<br />

position of a pedicle screw in a virtual reality display. The surgeon<br />

can then track his/her drill or awl in order to align it with the preplanned<br />

pathway of the screw. VectorVision spine contributes to<br />

lowering the risk of misplacem<strong>ent</strong> of screws and the complications<br />

that can occur such as a failed fusion.<br />

VECTORVISION� KNEE As VectorVision knee does not require<br />

diagnostic images or pre-operative planning, the <strong>system</strong> is a time<br />

and cost-effici<strong>ent</strong> solution, which can be used for every total<br />

knee replacem<strong>ent</strong> procedure. Using the VectorVision navigation<br />

<strong>system</strong> for a total knee replacem<strong>ent</strong> ensures more precise<br />

implantation of the prosthesis. The implant lifetime can thus be<br />

pot<strong>ent</strong>ially increased and the need of early revision surgeries<br />

considerably reduced.<br />

VECTORVISION� HIP With VectorVision hip, surgeons have the<br />

ability to semi-automatically select the perfect size and shape<br />

of an implant based on pre-operative 3-dimensional CT data of<br />

the respective pati<strong>ent</strong>. Leg length and range of leg movem<strong>ent</strong><br />

are simulated, ensuring the optimum implant is selected and set.<br />

During the surgical procedure, the surgeon is able to guide<br />

his/her saws, drills, and reamers to ensure correct implant placem<strong>ent</strong><br />

is carried out according to plan.


VECTORVISION� TRAUMA VectorVision trauma has been specially<br />

designed for trauma and emergency cases and offers intuitive<br />

navigation on bone structures. Based on navigation in intra-operative<br />

fluoroscopic images, VectorVision trauma supports the treatm<strong>ent</strong><br />

of fractures with interlocking nails and screws and therefore<br />

significantly reduces radiation exposure for pati<strong>ent</strong> and surgeon.<br />

BrainSCAN With BrainSCAN software, surgeons and physicists<br />

are able to outline tumors and critical structures on CT and MR<br />

images and then reconstruct all data in a 3-dimensional model. This<br />

3-D model is then used to establish the physical and geometric parameters<br />

of direct radiation beams to be aimed at the tumor. The goal<br />

is to minimize the dose received by critical structures while maximizing<br />

the dose received by the tumor. The “IMRT” option further automatizes<br />

the planning process while refining the dose distribution.<br />

NOVALIS� Novalis, BrainLAB’s dedicated <strong>system</strong> for non-invasive<br />

stereotactic radiosurgery and radiotherapy (SRS/SRT),<br />

repres<strong>ent</strong>s cutting-edge technology for highly precise treatm<strong>ent</strong>s<br />

of brain as well as head & neck tumors, arteriovenous malformations<br />

and certain functional disorders. Novalis Body features<br />

image-guided radiosurgery for high precision treatm<strong>ent</strong> of body<br />

targets. Based on its X-ray localization technology tumors can be<br />

localized with sub-millimeter accuracy and pati<strong>ent</strong>s can be positioned<br />

automatically and with a higher degree of precision. With<br />

Novalis Body, treatm<strong>ent</strong>s for spine, lung, liver and other body<br />

lesions can be carried out quickly and effici<strong>ent</strong>ly.<br />

m3� BrainLAB’s high-resolution multileaf collimator with its fine<br />

3 millimeter leaves has revolutionized radiosurgery by introducing<br />

conformal treatm<strong>ent</strong> techniques that allow the dose to be precisely<br />

tailored to the shape of the tumor. The reduced irradiation<br />

of normal tissue and the homogeneous dose distribution within<br />

the PTV contributes to superior and effici<strong>ent</strong> pati<strong>ent</strong> care.<br />

ExacTrac� X-ray The high-resolution x-ray imaging module features<br />

clinically-implem<strong>ent</strong>ed Image Guided Targeting as an upgrade<br />

for existing Linacs. The high quality imaging of internal structures<br />

and organs results in an extremely accurate setup of the target<br />

volume and overcomes the limitations of conv<strong>ent</strong>ional pati<strong>ent</strong><br />

positioning methods that are based on external skin markers.<br />

19


ENT<br />

BrainLAB headquarters,<br />

Munich, Germany<br />

20<br />

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