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#3 The non-LEE-encoded effectors

? The actual role of EHEC/EPEC effectors ¿

In vitro on cell cultures: origin of the cells

(species, organ)

Ex-vivo on IVOC, ligated loops: animal species,

intestinal segment

In vivo infection models: animal species, age

Extrapolation to humans

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#4 Differences between EHEC and EPEC EPEC1: a novel pathway (ex-vivo assays) EPEC 1 EPEC 2 & O157 EHEC non-O157 EHEC EPEC 1 From Schüller S. et al., Cellular Microbiol., 2007, 9, 1352-1364 12

#3 The non-LEE-encoded effectors ? The actual role of EHEC/EPEC effectors ¿ In vitro on cell cultures: origin of the cells (species, organ) Ex-vivo on IVOC, ligated loops: animal species, intestinal segment In vivo infection models: animal species, age Extrapolation to humans 13

Page 1 and 2: Enterohaemorrhagic and enteropathog
Page 3 and 4: #1 The attaching/effacing lesion St
Page 5 and 6: #2 The LEE-encoded effectors From G
Page 7 and 8: #2 The LEE-encoded effectors Hecht
Page 9 and 10: #3 The non-LEE-encoded effectors Na
Page 11: #4 Differences between EHEC and EPE
Page 15 and 16: #5 Discussion Host specificity of E
Page 17 and 18: Origin Calves (Diarrhea) Cattle (He

Enterohaemorrhagic and enteropathogenic Escherichia ... - eadgene

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