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Enterohaemorrhagic and enteropathogenic Escherichia ... - eadgene

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#2 The LEE-encoded effectors<br />

From Garmendia J. et al., Infect. Immun., 2005, 73, 2573-2585<br />

‣ ~50 genes <strong>and</strong> ORFs<br />

‣ 5 transcriptional units<br />

‣ Different insertion sites (selC, pheU, pheV, …)<br />

‣ Type III secretion machinery: esc/sep<br />

‣ Type-III-secreted translocator proteins: espA, espB, espD<br />

‣ Type-III translocated effectors: tir, espF, espG, espH, map, sepZ, ...<br />

5<br />

‣ Intimin adhesin: eae (type II-secreted outer membrane protein)

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