Enterohaemorrhagic and enteropathogenic Escherichia ... - eadgene
Enterohaemorrhagic and enteropathogenic Escherichia ... - eadgene
Enterohaemorrhagic and enteropathogenic Escherichia ... - eadgene
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#2 The LEE-encoded effectors<br />
From Garmendia J. et al., Infect. Immun., 2005, 73, 2573-2585<br />
‣ ~50 genes <strong>and</strong> ORFs<br />
‣ 5 transcriptional units<br />
‣ Different insertion sites (selC, pheU, pheV, …)<br />
‣ Type III secretion machinery: esc/sep<br />
‣ Type-III-secreted translocator proteins: espA, espB, espD<br />
‣ Type-III translocated effectors: tir, espF, espG, espH, map, sepZ, ...<br />
5<br />
‣ Intimin adhesin: eae (type II-secreted outer membrane protein)