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Indian Medicinal Plants

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Cinnamomum cassia Blume. 149<br />

Key application ◮ Externally in<br />

catarrhal diseases of the respiratory<br />

tract and muscular rheumatism;<br />

internally in hypotonic circulatory<br />

regulation disorders, Catarrhal<br />

diseases of the respiratory tract.<br />

(German Commission E.)<br />

The plant contains a volatile oil<br />

comprising camphor, safrole, linalool,<br />

eugenol and terpeneol. It also contains<br />

lignans (including secoisosolariciresinol<br />

dimethyl ether and kusunokiol).<br />

Safrole is thought to be carcinogenic.<br />

Theleafoilisanaturalsourceof<br />

linalool (94.9%); also contained citronellal<br />

(2.4%).<br />

Camphor in concentration of 500<br />

mcg/ml completely inhibits the growth<br />

of vibro parahaemolyticus, one of the<br />

causative agents of diarrhoea and dysentery.<br />

Ethanolic extract (50%) of<br />

fruits show antibacterial activity<br />

against several Gram-positive and<br />

Gram-negative bacteria. The essential<br />

oil from the plant possesses antifungal<br />

activity against many fungi.<br />

Camphor is toxic at 2–20 g.<br />

Dosage ◮ Concentrate—125–375 mg<br />

(CCRAS.)<br />

Cinnamomum cassia Blume.<br />

Synonym ◮<br />

Family ◮<br />

C. aromaticum Nees.<br />

Lauraceae.<br />

Habitat ◮ Native to China, Indonesia<br />

and Vietnam.<br />

English ◮ Chinese Cinnamon, Cassia<br />

Bark.<br />

Ayurvedic ◮ Tvak, Daalchini (bark).<br />

Siddha/Tamil ◮ Lavangappattai.<br />

Action ◮ Antispasmodic, carminative,<br />

antiputrescent, antidiarrhoeal,<br />

antiemetic, antimicrobial, mild<br />

analgesic. Used for flatulent<br />

dyspepsia, colic, irritable bowel,<br />

diverticulosis; also for influenza<br />

and colds.<br />

Key application ◮ In loss of appetite,<br />

dyspeptic complaints such as mild<br />

spasma of gastrointestinal tract,<br />

bloating, flatulence. (German<br />

Commission E, The British Herbal<br />

Pharmacopoeia, ESCOP.)<br />

The bark yields an essential oil containing<br />

cinnamaldehyde (82.2%) and<br />

eugenol (1.5%) as major constituents.<br />

Cinnamaldehyde is a weak CNS<br />

stimulant at low doses and a depressant<br />

at high doses and has spasmolytic<br />

activity. It is hypotensive, hypoglycaemic<br />

and increases peripheral blood<br />

flow; it reduces platelet aggregability<br />

by inhibiting both cyclooxygenase and<br />

lipoxygenase pathways of arachidonic<br />

acid metabolism.<br />

Aqueous extract of the bark shows<br />

significant antiallergic activity in<br />

guinea pig. Diterpenes (Cinncassiols)<br />

are thought to be responsible for<br />

atleast some of the antiallergic effects.<br />

The herb inhibited ulcers induced<br />

by ethanol, also ulcers induced by<br />

phenylbutazone; failed to prevent ulcers<br />

induced by indomethacin. (Planta<br />

Med 1989,55(3),245–248.)<br />

The extract, when administered<br />

orally to rats with nephritis, prevents<br />

the increase of protein level in urine.<br />

The bark markedly reduces blood<br />

pressure in experimental rats; exhibits<br />

tranquilizing effect and is used as<br />

C

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