2010 Best Practices Competition IT & Informatics HPC

More documents

Recommendations

Info

Published Resources for the Life Sciences 250 First Avenue, Suite 300, Needham, MA 02494 | phone: 781‐972‐5400 | fax: 781‐972‐5425 Instruments and platform data repositories Cellomics Store database Reagent and cell line registries Enterprise results repository HCS Road Data Explorer ArrayScan Image share Image + Data share Services Image Conversion Third-party tools (TIBCO Spotfire) Opera InCell 1000 Image + Data share File share Database HCS Road FIG. 1. Overview of HCS Road components showing data flow from HCS instruments through the HCS Road database and file share to data analysis and visualization tools. Blue icons designate instrument-specific databases and file shares. Green arrows and green box indicate HCS Road components. Gray arrows indicate data import or export to existing enterprise databases or third-party analysis tools.
Published Resources for the Life Sciences 250 First Avenue, Suite 300, Needham, MA 02494 | phone: 781‐972‐5400 | fax: 781‐972‐5425 Library Definition (external) Register Reagents Define Plate maps Register Barcodes Assay Definition Define or Select select Cell Line fluorescent probes Enter Business Define or Metadata select • Client group additional • Program compounds Define master plate layout • Cell line(s) • Seeding density •Probes • Control/reference treatments Create Assay Plates Analysis Definition Select Measurements for analysis Designate control treatments for measurement • Well-level •Cell-level Data Loading & Analysis Create Imaged Plates Calculate QC Metrics • Z’ •Mean •CV Review results Reject outliers Images & Data from HCS reader/software Analyze Data Publish results to enterprise results database FIG. 2. Workflow for experiment definition, data import and analysis. White boxes show workflow steps and colored boxes indicate functional subsets of the process. Black arrows indicate workflow progression and dependencies between steps.
Page 1 and 2: 2010 Best Practices Competition IT
Page 3 and 4: B. INTRODUCTION/background/objectiv
Page 5 and 6: Published Resources for the Life Sc
Page 15: Published Resources for the Life Sc
Page 21 and 22: Results: Purdue selected the free,
Page 23 and 24: CAC network connectivity includes t
Page 29 and 30: Bio‐IT World 2010 Best Practices
Page 43 and 44: 1. User Organization (Organization
Page 45 and 46: Figure 1 Data processing Pipeline (
Page 47 and 48: the cluster grind to a halt. The ke
Page 49 and 50: Figure 2 Saguaro2 supercomputer In
Page 51 and 52: [ROI Expected or Achieved] Figure 4

2010 Best Practices Competition IT & Informatics HPC

Create successful ePaper yourself

Delete template?

Save as template?