2010 Best Practices Competition IT & Informatics HPC

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Results: Using scale‐out NAS from Isilon Systems, OMRF has unified both its DNA sequencing pipeline and virtualized computing infrastructure into a single, high performance, highly scalable, shared pool of storage, simplifying its IT environment and significantly speeding time‐to‐results. OMRF can now scale its storage system on‐demand to meet the rapid data growth and unique performance demands of its mission‐critical workflow, increasing operational efficiency and decreasing costs in an effort to identify genetic precursors to diseases such as Alzheimer’s, Lupus and Sjögren’s Syndrome. With its scale‐out NAS solution, OMRF has created a single, highly reliable central storage resource for both its entire next‐generation sequencing workflow and its virtual computing infrastructure, dramatically simplifying storage management and streamlining data access across its organization. Today, OMRF can cost‐effectively manage rapid data growth from a single file system, eliminating data fragmentation caused by traditional NAS in virtual environments and maximizing the performance of both its virtual servers and its DNA sequencing workflow. By deploying a second Isilon system off‐site and using Isilon’s SyncIQ® asynchronous data replication software to replicate data between its primary and off‐site clusters, OMRF also has a highly reliable solution in place to ensure its data is immediately available even in the case of IT failure or natural disaster. ROI achieved: Conclusions: References:
Published Resources for the Life Sciences 250 First Avenue, Suite 300, Needham, MA 02494 | phone: 781‐972‐5400 | fax: 781‐972‐5425 Bio‐IT World 2010 Best Practices Awards 1. Nominating Organization (Fill this out only if you are nominating a group other than your own.) A. Nominating Organization Organization name: Address: B. Nominating Contact Person Name: Title: Tel: Email: 2. User Organization (Organization at which the solution was deployed/applied) A. User Organization Organization name: National Institute of Allergy and Infectious Diseases (NIAID) Address: 10401 Fernwood Rd., Bethesda, MD 20892 B. User Organization Contact Person Name: Nick Weber Title: Scientific Informatics & Infrastructure Analyst Tel: 301.594.0718 Email: webermn@niaid.nih.gov 3. Project Project Title: A Centralized and Scalable Infrastructure Approach to Support Next Generation Sequencing at the National Institute of Allergy and Infectious Diseases Team Leader Name: Nick Weber (Lockheed Martin Contractor) Title: Scientific Informatics & Infrastructure Analyst Tel: 301.594.0718 Email: webermn@niaid.nih.gov Team members – name(s), title(s) and company (optional): • Vivek Gopalan – Scientific Infrastructure Lead (Lockheed Martin Contractor) • Mariam Quiñones – Computational Molecular Biology Specialist (Lockheed Martin Contractor) • Hugo Hernandez – Senior Systems Administrator (Dell Perot Systems Contractor) • Robert Reed – Systems Administrator (Dell Perot Systems Contractor) • Kim Kassing – Branch Chief, Operations and Engineering Branch (NIAID Employee)
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2010 Best Practices Competition IT & Informatics HPC

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