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A Review of immunomodulators with reference to Canova - Similima

A Review of immunomodulators with reference to Canova - Similima

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TLR ‘s are recognition recep<strong>to</strong>rs that are activated by<br />

specific components, microbes & certain host molecules<br />

13 mamallian TLR’s which can be activated by pathogens<br />

(Exogenous) & immune related (endogenous) are<br />

identified<br />

An Ag when taken up by an APC, the TLR ‘s are stimulated<br />

Increase MHC Ag & cy<strong>to</strong>kine production<br />

Stimulate other APC’s & T & B Lymphocytes<br />

Proper immune response<br />

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