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Treatment Alternatives in Charcot Arthropathy of the Foot

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CASE STUDY<br />

<strong>Treatment</strong><br />

<strong>Alternatives</strong><br />

<strong>in</strong> <strong>Charcot</strong><br />

<strong>Arthropathy</strong><br />

<strong>of</strong> <strong>the</strong> <strong>Foot</strong><br />

Early postoperative phase with foot stabilized<br />

<strong>in</strong> th<strong>in</strong>-wire frame construct.<br />

A patient avoids amputation<br />

A 72-year-old man with type 2 diabetes mellitus<br />

was referred to Duke Medic<strong>in</strong>e <strong>in</strong> October 2014<br />

for treatment <strong>of</strong> <strong>Charcot</strong> arthropathy <strong>of</strong> <strong>the</strong> foot,<br />

a sequela <strong>of</strong> diabetes. Although his blood glucose<br />

levels had been well controlled for 5 to 6 years,<br />

he developed numbness, pa<strong>in</strong>, and peripheral<br />

neuropathy <strong>in</strong> both feet.<br />

In October 2014, he was referred to a local<br />

orthopaedic surgeon who diagnosed <strong>Charcot</strong><br />

arthropathy <strong>of</strong> <strong>the</strong> midfoot based on radiographic<br />

f<strong>in</strong>d<strong>in</strong>gs. Due to severe arthropathy, osteomyelitis,<br />

and sk<strong>in</strong> ulceration, <strong>the</strong> patient was <strong>of</strong>fered<br />

below-<strong>the</strong>-knee amputation or referral for a<br />

second op<strong>in</strong>ion.<br />

“<strong>Charcot</strong> arthropathy is an uncommon complication<br />

<strong>in</strong> patients with long-stand<strong>in</strong>g diabetes<br />

and peripheral neuropathy,” says Beatrice Hong,<br />

MD, a diabetologist at Duke, who did not treat<br />

<strong>the</strong> patient. “The presentation is variable, <strong>in</strong>itially<br />

with warmth and swell<strong>in</strong>g that progresses <strong>in</strong>to a<br />

characteristic collapse <strong>of</strong> <strong>the</strong> arch <strong>of</strong> <strong>the</strong> midfoot,<br />

result<strong>in</strong>g <strong>in</strong> bony prom<strong>in</strong>ences.”<br />

One month earlier, <strong>the</strong> patient had noticed<br />

redness and swell<strong>in</strong>g <strong>in</strong> his left foot and was<br />

treated for presumptive cellulitis. Fragmentation<br />

went unnoticed on radiographs. He cont<strong>in</strong>ued<br />

walk<strong>in</strong>g on <strong>the</strong> foot and developed a sk<strong>in</strong> ulcer<br />

on <strong>the</strong> lateral plantar aspect. Subsequently, he<br />

received local debridement and more antibiotics.<br />

If it is diagnosed before destructive changes <strong>of</strong><br />

<strong>the</strong> bone/jo<strong>in</strong>t take place, <strong>Charcot</strong> arthropathy<br />

can <strong>of</strong>ten be managed with cast<strong>in</strong>g, <strong>of</strong>fload<strong>in</strong>g<br />

braces, custom shoes, and orthotic devices.<br />

However, when <strong>the</strong> bones and jo<strong>in</strong>ts have become<br />

unstable, fragmented, and malaligned with<br />

compromised sk<strong>in</strong> and s<strong>of</strong>t tissue, surgery is<br />

typically necessary. Reconstructive surgery might<br />

be a viable option to avoid amputation.<br />

In <strong>Charcot</strong> arthropathy <strong>of</strong> <strong>the</strong> foot, <strong>the</strong> goal <strong>of</strong><br />

surgical <strong>in</strong>tervention is to realign and stabilize <strong>the</strong><br />

foot with osteotomies, arthrodesis, and <strong>in</strong>ternal<br />

and/or external fixation. Unfortunately, <strong>the</strong> foot<br />

cannot always be salvaged, and amputation may<br />

be necessary for some patients. Many factors<br />

10 Cl<strong>in</strong>ical Practice Today from Duke Medic<strong>in</strong>e

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